The Caenorhabditis elegans DPF‐3 and human DPP4 have tripeptidyl peptidase activity
FEBS Letters, EarlyView.The dipeptidyl peptidase IV (DPPIV) family comprises serine proteases classically defined by their ability to remove dipeptides from the N‐termini of substrates, a feature that gave the family its name. Here, we report the discovery of a previously unrecognized tripeptidyl peptidase activity in DPPIV family members from two different species.
Aditya Trivedi, Rajani Kanth Gudipati
wiley +1 more source
Novel score test to increase power in association test by integrating external controls. [PDF]
Genet Epidemiol, 2021 Li Y, Lee S.
europepmc +1 more source
On large-sample estimation and testing via quadratic inference functions for correlated data [PDF]
, 2005 Hansen (1982) proposed a class of "generalized method of moments" (GMMs) for estimating a vector of regression parameters from a set of score functions.
Loader, Catherine, Pilla, Ramani S.
core
Molecular bases of circadian magnesium rhythms across eukaryotes
FEBS Letters, EarlyView.Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley +1 more source
Speeding up Monte Carlo simulations for the adaptive sum of powered score test with importance sampling. [PDF]
Biometrics, 2022 Deng Y, He Y, Xu G, Pan W.
europepmc +1 more source
Dementia and Primary-Care Health Measures:Hearing, Gait, and Markers of Inflammation [PDF]
, 2015 Dementia is a syndrome associated with declining cognitive function that has a variety of types and causes, and is encountered frequently in general medical practice. Researchers are actively exploring possible risk factors for dementia. The St.
Lindgren, Elsa
core +1 more source
Peptide‐based ligand antagonists block a Vibrio cholerae adhesin
FEBS Letters, EarlyView.The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang +9 more
wiley +1 more source
Erratum: Clinical analysis of 21-gene relapse score test in hormone receptor-positive early-stage breast cancer. [PDF]
Oncol Lett, 2021 Zhu L +7 more
europepmc +1 more source
Measurement of coronary calcium scores by electron beam computed tomography or exercise testing as initial diagnostic tool in low-risk patients with suspected coronary artery disease [PDF]
, 2007 Christiane A Geluk +10 more
openalex +1 more source
2011-2012 Arkansas Test Results [PDF]
, 2012 On Monday, July 30, the Arkansas Department of Education (ADE) released the 2011-2012 test score results. The following brief will highlight the results of these tests, compare achievement scores over time, and provide a glimpse of regional achievement ...
Greenwood, Reed, Ritter, Gary W.
core +2 more sources