Results 141 to 150 of about 5,580 (197)

Targeted Metabolomics of <i>Tityus</i> Scorpion Venoms: Unveiling Small-Molecule Components. [PDF]

J Am Soc Mass Spectrom
Dias NB, Monson de Souza B, Barroso G, Leiva JO, Paula GM, Chalkidis HM, Dorce VAC, Malaspina O, Palma MS.   +8 more
europepmc   +1 more source

Southern African scorpion toxins: An overview

Toxicon, 2008
In southern Africa there are 130 species of scorpions and only a few species' venom have been investigated to date. This review gives an overview of the research done on the venom of southern African scorpions and the toxins and peptides identified up to date.
Du Plessis, L.H., Elgar, D., Du Plessis, J.L.   +2 more
openaire   +4 more sources

Adaptive Evolution of Scorpion Sodium Channel Toxins

Journal of Molecular Evolution, 2004
Gene duplication followed by positive Darwinian selection is an important evolutionary event at the molecular level, by which a gene can gain new functions. Such an event might have occurred in the evolution of scorpion sodium channel toxin genes (alpha- and beta-groups).
Zhu, Shunyi, Bosmans, Frank, Tytgat, Jan
openaire   +4 more sources

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Deduction of functional peptide motifs in scorpion toxins

Journal of Peptide Science, 2006
AbstractScorpion toxins are important physiological probes for characterizing ion channels. Molecular databases have limited functional annotation of scorpion toxins. Their function can be inferred by searching for conserved motifs in sequence signature databases that are derived statistically but are not necessarily biologically relevant.
Shoba Ranganathan, Vladimir Brusic
exaly   +6 more sources

Scorpion-Toxins Lqh-3

, 2010
In deep review on the pharmacology and toxicology of scorpion toxin Lqh3.
CATALDI, MAURO, Mauro Cataldi
openaire   +4 more sources

Scorpion Alpha-Toxins Lqh-2☆

, 2009
In deep review of the pharmacology and toxicology of scorpion toxin Lqh2.
CATALDI, MAURO
openaire   +3 more sources

SCORPION2: A database for structure–function analysis of scorpion toxins

Toxicon, 2006
Scorpion toxins are important experimental tools for characterization of vast array of ion channels and serve as scaffolds for drug design. General public database entries contain limited annotation whereby rich structure-function information from ...
Shoba Ranganathan, Vladimir Brusic
exaly   +2 more sources

[Scorpion toxins].

Comptes rendus des seances de la Societe de biologie et de ses filiales, 1997
Scorpion are known to use a cocktail of toxins to immobilize their prey. So, their venoms constitute a complex mixture of polypeptides exhibiting different pharmacological activities. These polypeptides are small (between 30 and 70 amino acids long), basic and highly reticulated (3 or 4 disulfide bridges).
C, Legros, M F, Martin-Eauclaire
openaire   +3 more sources

SCORPION, a molecular database of scorpion toxins

Toxicon, 2002
Increasing interest in the studies of toxins and the requirements for better structural and functional annotations have created a need for improved data management in the field of toxins. The molecular database, SCORPION, contains more than 200 entries of fully referenced scorpion toxin data including primary sequences, three-dimensional structures ...
Srinivasan, K.N., Gopalakrishnakone, P., Tan, P.T., Chew, K.C., Kini, R.M., Cheng, B., Koh, J.L.Y., Seah, S.H., Brusic, V.   +8 more
openaire   +2 more sources

Comparative pharmacology and cloning of two novel arachnid sodium channels: Exploring the adaptive insensitivity of scorpion to its toxins

FEBS Letters, 2006
Scorpion toxins have been found lacking effect on Na+ current of its own sodium channel, whereas the molecular mechanism remains mystery. In this study, the binding affinity of pharmacologically distinct scorpion toxins was found much weaker to scorpion (
Ming He, Yong-Hua Ji
exaly   +2 more sources