Isolation, chemical and functional characterization of several new K+-channel blocking peptides from the venom of the scorpion Centruroides tecomanus [PDF]
K
Balajthy, András +6 more
core +1 more source
Scorpions use their venom in defensive situations as well as for subduing prey. Since some species of scorpion use their venom more in defensive situations than others, this may have led to selection for differences in effectiveness in defensive ...
Arie van der Meijden +4 more
doaj +1 more source
Moral Luck and Deviant Causation [PDF]
This paper discusses a puzzling tension in attributions of moral responsibility in cases of resultant moral luck: we seem to hold agents fully morally responsible for unlucky outcomes, but less-than-fully-responsible for unlucky outcomes brought about ...
Bernstein, Sara
core
Phyla- and Subtype-Selectivity of CgNa, a Na+ Channel Toxin from the Venom of the Giant Caribbean Sea Anemone Condylactis Gigantea [PDF]
Because of their prominent role in electro-excitability, voltage-gated sodium (Na(V)) channels have become the foremost important target of animal toxins.
Bert Billen +4 more
core +2 more sources
Spider neurotoxins targeting voltage-gated sodium channels [PDF]
The voltage-gated sodium (Nav) channel is a target for a number of drugs, insecticides, and neurotoxins. These bind to at least seven identified neurotoxin binding sites and either block conductance or modulate sodium channel gating and/or kinetics.
Little, MJ, Nicholson, GM
core +1 more source
Sequencing and comparative-bioinformatic analysis of chlorotoxin-like peptide from Iranian scorpion Mesobuthus eupeus [PDF]
زمینه و هدف: در سال های اخیر نوروتوکسین های عقرب از لحاظ خواص دارویی و اثرات فیزیولوژیک مورد مطالعات زیادی قرار گرفته اند. یکی از این توکسین ها که توجه زیادی را به خود جلب کرده است، کلروتوکسین می باشد که هم اکنون در درمان سرطان های مغز مورد استفاده قرار ...
Ahadi, AliMohammad. +3 more
core +1 more source
Evolution Stings: The Origin and Diversification of Scorpion Toxin Peptide Scaffolds
The episodic nature of natural selection and the accumulation of extreme sequence divergence in venom-encoding genes over long periods of evolutionary time can obscure the signature of positive Darwinian selection.
Kartik Sunagar +6 more
doaj +1 more source
Cardiogenic shock requiring VA‐ECMO therapy in scorpionism‐induced myocarditis
ESC Heart Failure, Volume 12, Issue 5, Page 3780-3784, October 2025.
Alba I. Violino +5 more
wiley +1 more source
Understanding the complexity of Tityus serrulatus venom: A focus on high molecular weight components [PDF]
Tityus serrulatus scorpion is responsible for a significant number of envenomings in Brazil, ranging from mild to severe, and in some cases, leading to fatalities. While supportive care is the primary treatment modality, moderate and severe cases require
Isadora Sousa de Oliveira +7 more
doaj +1 more source
Novel conopeptides of largely unexplored Indo Pacific Conus sp. [PDF]
Cone snails are predatory creatures using venom as a weapon for prey capture and defense. Since this venom is neurotoxic, the venom gland is considered as an enormous collection of pharmacologically interesting compounds having a broad spectrum of ...
D'Souza, L. +9 more
core

