Results 71 to 80 of about 11,746 (218)

Polysaccharide Adjuvants as Innate Immune Trainers: Bridging Pattern Recognition Receptor (PRR) Activation and Metabolic Reprogramming for Synthetic Vaccine Design

Advanced Science, Volume 12, Issue 48, December 29, 2025.
Polysaccharides modulate immune responses by engaging pattern recognition receptors (PRRs) to induce T‐cell activation. In vaccine design, their particle size critically influences lymph node targeting and activation mechanisms. By engineering structural complexity and multivalent PRR engagement, polysaccharides enable precise modulation of immune ...
Jeong Hyun Moon, May Thazin Phoo, Yubin Kim, Jinsung Ahn, April Kim, Jutaek Nam, Soo‐Hong Lee, James J. Moon, Sejin Son   +8 more
wiley   +1 more source

Antiviral activity of animal venom peptides and related compounds [PDF]

, 2017
Viruses exhibit rapid mutational capacity to trick and infect host cells, sometimes assisted through virus-coded peptides that counteract host cellular immune defense.
Mata, Élida Cleyse Gomes da Mata, Mourão, Caroline Barbosa Farias, Rangel, Marisa, Schwartz, Elisabeth Nogueira Ferroni   +3 more
core   +2 more sources

Scorpions and their Venom [PDF]

Nature, 1922
PHYSALIA in “Animaux Venimeux,” p. 252, says that in all venomous animals their immunity to their own venom is limited, and announces that in an experiment a scorpion, Bulteus australis, was killed by an injection of the same venom as its own. I should like to add further observations from personal experience, bearing on this very interesting subject.
openaire   +1 more source

Pond frog as a predator of hornet workers: High tolerance to venomous stings

Ecosphere, Volume 16, Issue 12, December 2025.
Abstract Some animals use stingers to repel attackers, and some predators have evolved tolerance to such stings, enabling them to consume venomous prey. For example, social wasps, such as hornets, use modified ovipositors as venomous stingers to inject venom, which can cause intense pain in humans.
Shinji Sugiura
wiley   +1 more source

Insect- and vertebrate-selective neurotoxins from Australian urodacid and buthid scorpion venoms : lead compounds for novel biopesticides [PDF]

, 2003
University of Technology, Sydney. Department of Health Sciences.Scorpions from nine species were collected from locations across Australia comprising four Lychas (Buthidae), four Urodacus (Urodacidae) and one Cercophonius (Bothriuridae) .
Wilson, HL
core  

A Cell‐Penetrating Scorpion Venom Peptide Disrupts the HSP90β‐PPARα Interaction to Ameliorate Metabolic Dysfunction‐Associated Steatotic Liver Disease

iMetaMed, Volume 1, Issue 2, December 2025.
In MASLD, increased HSP90β interacts with PPARα, thereby inhibiting PPARα activation via the inhibition of its nuclear translocation. BmK Tx‐2, a cell‐penetrating peptide from Buthus martensii Karsch scorpion venom, enters hepatocytes via macropinocytosis and escapes endosomes to bind HSP90β.
Erjin Xu, Wuguang Lu, Yonggen Chen, Ming Sang, Jiao Chen, Xueting Cai, Wenhao Xu, Yuxin Zhang, Zhiheng Wang, Feng Zhang, Peng Cao   +10 more
wiley   +1 more source

Transcriptome analysis of the venom gland of the Mexican scorpion Hadrurus gertschi (Arachnida: Scorpiones)

BMC Genomics, 2007
Background Scorpions like other venomous animals posses a highly specialized organ that produces, secretes and disposes the venom components. In these animals, the last postabdominal segment, named telson, contains a pair of venomous glands connected to ...
Rodríguez de la Vega Ricardo C, Diego-Garcia Elia, Schwartz Elisabeth F, Possani Lourival D   +3 more
doaj   +1 more source

Medicinal and ethnoveterinary remedies of hunters in Trinidad [PDF]

, 2001
Background Ethnomedicines are used by hunters for themselves and their hunting dogs in Trinidad. Plants are used for snakebites, scorpion stings, for injuries and mange of dogs and to facilitate hunting success. Results Plants used include Piper hispidum,
M Heinrich, NL Etkin, S Moodie-Kublalsingh, R Wall, ME Alkins, SA Nishioka, JC Murphy, MT Jorge, J Kenny, LD George Angus, MJ Hutt, P Melo, JO Boos, CH Browner, G Bourdy, WH Hodge, DS Nunes, J Serpell, EB Russo, EF Im Thurn, E Roth Walter, RR Mole, PA Dennis, D Hazlett, JA Duke, MJ Martínez-Lirola, AB Carr, E Davis, W Wilbert, Bonnie Beaver, G Urton, WV Branan, AL Fuly, I Francischetti, R Otero, HC Castro, L Thomas, NA Pereira, H Wagner, PJ Houghton, R Ejzemberg, MS Abubakar, W Martz, R Reyes-Chilpa, O Castro, PA Melo, A Borges, H Daisley, CM McCorkle, JA Duke, JF Morton, W Wong, FG Coe, DA Lachman-White, LM Girón, JJ Moreno, C Yoosook, P Tuntiwachwuttikul, RH Cichewicz, H Wagner, B Frei, AA Al-Qarawi, SC Comerford, W Wilbert, PN Honychurch, R Verpoorte, R Otero, I Indrayanto, K Inoue, E Osim, J Laferriere, W Setzer, MW Bernart, WB Mors, Anon, AJJ Van den Berg, LF Villegas, C Hufford, IT Matsuse, RP Labadie, JF Morton, JF Morton, S Horsten, JF Morton, RE Omoregbe, B Das, C Auvin-Guette, WD MacRae, JX de-Vries, MP Gupta, J Mills, C Desmarchelier, JA Duke, C Desmarchelier, C Desmarchelier, C Desmarchelier, E Mongelli, WR Stimson, ML Tan, R Hegnauer, T Plowman, MA Kay, R Hansel, R Hegnauer, L Joly, V Muñoz, T Arnason, FG Coe, JB Calixto, NV Rajeshkumar, KCS Chen Liu, KS Satyan, ARS Santos, B Burke, MO Nwosu, K Jenett-Siems, H Hirschhorn, F Ayala Flores, B-N Zhou, J-L Longuefosse, R Novaretti, D Rivera, E Yesilada, E Blanco, A Cáceres, R Hegnauer, R Hegnauer, A Filipov, A Cáceres, G Schmeda-Hirschmann, VS Frutuoso, AK Bhargava, FI Freire M de, J Jakupovic, S Borkosky, R Hegnauer, R Otero, C Lans   +137 more
core   +2 more sources

Intervertebral Disc Proteoglycans: Multifunctional Tissue Stabilizing and Instructional Cell Regulatory Proteins That Control Tissue Homeostasis

JOR SPINE, Volume 8, Issue 4, December 2025.
Matrix and cell‐associated proteoglycans are important tissue‐stabilizing, weight‐bearing, and tension‐resisting proteins in the intervertebral disc. Their glycosaminoglycan components have growth factor binding and cell‐instructive properties that allow cells to regulate tissue composition and function.
James Melrose
wiley   +1 more source

Isolation and Characterization of Insecticidal Toxins from the Venom of the North African Scorpion, Buthacus leptochelys

Toxins, 2019
Various bioactive peptides have been identified in scorpion venom, but there are many scorpion species whose venom has not been investigated. In this study, we characterized venom components of the North African scorpion, Buthacus leptochelys, by mass ...
Yusuke Yoshimoto, Masahiro Miyashita, Mohammed Abdel-Wahab, Moustafa Sarhan, Yoshiaki Nakagawa, Hisashi Miyagawa   +5 more
doaj   +1 more source