Results 71 to 80 of about 6,814 (206)

Patterns and Outcomes of Poisoning Among Older Adults in Thailand: A Four‐Year Retrospective Analysis From the Siriraj Poison Control Center

Clinical and Translational Science, Volume 19, Issue 1, January 2026.
ABSTRACT Poisoning among older adults poses unique challenges due to age‐related physiological changes, polypharmacy, and comorbidities. As Thailand transitions to a super‐aged society, this study characterizes poisoning patterns in Thai older adults to inform prevention strategies.
Pornchanok Monkaew, Nerisa Thornsri, Pattaraporn Mekavuthikul, Junporn Kongwatcharapong   +3 more
wiley   +1 more source

Animal Venom Pharmacological Resources: Exploiting Bioactive Peptides to Target Multi–Drug‐Resistant Bacteria

Biochemistry Research International, Volume 2026, Issue 1, 2026.
Background The escalating rise of multi–drug‐resistant (MDR) bacterial strains significantly threatens global health, creating a “silent pandemic” prompted by natural selection, gene mutation, and horizontal gene transfer. This crisis is worsened by the deficit in the development of new treatments, necessitating the innovative discovery of new potent ...
Rima Jaber, César Mattei, Claudine Accary, Rabih Roufayel, Ziad Abi Khattar, Ziad Fajloun, Yoel A. Klug   +6 more
wiley   +1 more source

Animal Venoms as Peptide Libraries for the Discovery of Antiglioblastoma Agents

Biochemistry Research International, Volume 2026, Issue 1, 2026.
Glioblastoma is one of the most aggressive and widely recognized types of brain tumors, characterized by significant cellular and molecular diversity and an inherently aggressive nature. The treatment remains highly challenging, with limited effectiveness and persistently low survival rates.
Livia Ramos Santiago, Edgar Alejandro Pinos Tamayo, Daniel Moreira dos Santos, Bonglee Kim, José R. Almeida, Rosy Iara Maciel de Azambuja Ribeiro, Marco Eigenfeld   +6 more
wiley   +1 more source

ScorpDb: A Novel Open-Access Database for Integrative Scorpion Toxinology

Toxins
Scorpion stings are a significant public health concern globally, particularly in tropical and subtropical regions. Scorpion venoms contain a diverse array of bioactive peptides, and different scorpion species around the world typically exhibit varying ...
Masoumeh Baradaran, Fatemeh Salabi, Masoud Mahdavinia, Elaheh Mohammadi, Babak Vazirianzadeh, Ignazio Avella, Seyed Mahdi Kazemi, Tim Lüddecke   +7 more
doaj   +1 more source

Short-chain peptides identification of scorpion Buthus martensi Karsch venom by employing high orthogonal 2D-HPLC system and tandem mass spectrometry

, 2012
Scorpion venom contains a considerable variety of neurotoxic peptides that can act on ionic channels. Here, we describe an orthogonal 2D-reversed phase/hydrophilic interaction chromatography system (RPLC/HILIC) and use it to separate short-chain peptides
Xue, Xingya, Yu, Long, Yan, Jingyu, Liang, Xinmiao, Li, Xiuling, 梁鑫淼, Zhang, Xiuli, Guo, Zhimou, Xu, Junyan   +8 more
core   +1 more source

Embryotoxicity following repetitive maternal exposure to scorpion venom [PDF]

, 2012
Although it is a frequent accident in a few countries, scorpion envenomation during pregnancy remains scarcely studied. In the present study, the effects of repetitive maternal exposure to Buthus occitanus tunetanus venom are investigated and its ...
H Serria, BN Hmed, B Riadh, J Kamel, Z Khaled   +4 more
core   +1 more source

Scorpion Venom and Its Different Peptides Aid in Treatment Focusing on Cancer Disease with the Mechanism of Action

Trends in Pharmacy
Animal venoms, especially those from scorpions, have garnered interest for their potential therapeutic uses. Scorpion venom is a complex mixture of bioactive compounds, including neurotoxins, enzymes, enzyme inhibitors, and peptides. These peptides have
Radwa Abdallnasser Amen, Gamal Eldein Fathy Abd-Ellatef   +1 more
doaj   +5 more sources

First‐Aid Practices and Knowledge Regarding Snake and Scorpion Bites Among Patients Attending Onandjokwe State Hospital, Namibia: A Hospital‐Based Cross‐Sectional Study

Emergency Medicine International, Volume 2026, Issue 1, 2026.
Background Snake and scorpion bites pose a significant public health burden, with an estimated global annual morbidity rate of 5.4 million and 1.2 million, respectively. Various first‐aid methods are commonly practiced in communities, aiming to improve the chances of survival after bites.
Petrus Uushona, Albertina M. N. Shatri, Jincheng Wang   +2 more
wiley   +1 more source

Polysaccharide Adjuvants as Innate Immune Trainers: Bridging Pattern Recognition Receptor (PRR) Activation and Metabolic Reprogramming for Synthetic Vaccine Design

Advanced Science, Volume 12, Issue 48, December 29, 2025.
Polysaccharides modulate immune responses by engaging pattern recognition receptors (PRRs) to induce T‐cell activation. In vaccine design, their particle size critically influences lymph node targeting and activation mechanisms. By engineering structural complexity and multivalent PRR engagement, polysaccharides enable precise modulation of immune ...
Jeong Hyun Moon, May Thazin Phoo, Yubin Kim, Jinsung Ahn, April Kim, Jutaek Nam, Soo‐Hong Lee, James J. Moon, Sejin Son   +8 more
wiley   +1 more source

Transcriptome analysis of the venom gland of the Mexican scorpion Hadrurus gertschi (Arachnida: Scorpiones)

BMC Genomics, 2007
Background Scorpions like other venomous animals posses a highly specialized organ that produces, secretes and disposes the venom components. In these animals, the last postabdominal segment, named telson, contains a pair of venomous glands connected to ...
Rodríguez de la Vega Ricardo C, Diego-Garcia Elia, Schwartz Elisabeth F, Possani Lourival D   +3 more
doaj   +1 more source