Results 61 to 70 of about 6,839 (205)

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, Volume 20, Issue 6, Page 1398-1419, June 2026.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

Venomics of the scorpion Tityus ocelote (Scorpiones, Buthidae): Understanding venom evolution in the subgenus Archaeotityus

International Journal of Peptide Research and Therapeutics, 2022
AbstractThe subgenusTityus (Archaeotityus)includes small variegated species considered until recently, a basal group withinTityus, one of the most diverse and medically relevant genera of scorpions in the New World.Archaeotityusspecies are distributed in the humid forests of Lower Central America and the Choco, Guiana Shield, and Amazon regions. Due to
Díaz Oreiro, Cecilia, Chang Castillo, Arturo, Lomonte, Bruno, Bonilla Murillo, Fabián, Víquez, Carlos, Alfaro Chinchilla, Adriana, Triana Ricón, Felipe, Sasa Marín, Mahmood   +7 more
openaire   +2 more sources

Reduced Toxicity of Centruroides vittatus (Say, 1821) May Result from Lowered Sodium β Toxin Gene Expression and Toxin Protein Production

Toxins, 2021
Body tissue and venom glands from an eastern population of the scorpion Centruroides vittatus (Say, 1821) were homogenized and molecular constituents removed to characterize putative sodium β toxin gene diversity, RT-qPCR, transcriptomic, and proteomic ...
Aimee Bowman, Chloe Fitzgerald, Jeff F. Pummill, Douglas D. Rhoads, Tsunemi Yamashita   +4 more
doaj   +1 more source

Exploring Floristic Diversity and Medicinal Plant Uses in Venda, Limpopo, South Africa

Feddes Repertorium, Volume 137, Issue 2, June 2026.
ABSTRACT Plants have been an important source of medicine for thousands of years. To better understand the current diversity and usage of medicinal plants, floristic studies are essential. This report documents an expedition conducted in the Venda region of Limpopo, South Africa. The study was carried out in Shanzha and surrounding villages, as well as
Gurusamy Manikandan, Iliassou L. Mouafon, David R. Katerere   +2 more
wiley   +1 more source

Investigation of in vivo potential of scorpion venom against skin tumorigenesis in mice via targeting markers associated with cancer development [PDF]

, 2016
Abdulrahman K Al Asmari, Abdul Quaiyoom Khan Research Centre, Prince Sultan Military Medical City, Riyadh, Saudi Arabia Abstract: Cancer is the leading cause of morbidity and mortality all over the world in spite of the advances made in its management.
Khan AQ, Al Asmari AK
core  

Conkazal‐M1 from the MKAVA family of conotoxins: A dual‐function protease inhibitor and neuroactive peptide

Protein Science, Volume 35, Issue 5, May 2026.
Abstract Marine cone snails produce a diverse array of bioactive peptides, known as conotoxins, in their venom. Given their high target potency and specificity, conotoxins are attractive compounds for the development of precision research tools and pharmacological agents.
Celeste M. Hackney, Thomas Lund Koch, Nicklas Lund Ryding, Aymeric Rogalski, Kevin Chase, Matías Leonel Giglio, Samuel S. Espino, Zildjian G. Acyatan, Maren Watkins, Baldomero M. Olivera, Helena Safavi‐Hemami, Kaare Teilum, Lars Ellgaard   +12 more
wiley   +1 more source

Os possíveis mediadores envolvidos na gênese da hiperalgesia induzida pela administração do veneno bruto de Tityus serrulatus (Escorpião-amarelo) em patas de rato [PDF]

, 2000
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências Biológicas.Ocorre em torno 10 mil casos de acidentes por ano no Brasil, causados por escorpião amarelo, sendo que o sintoma mais expressivo do envenenamento relatado por ...
Nowacki, Luciana Cristina
core  

Predation Under Heat Stress: The Significance of Body Size to the Outcome of an Acarine Predator–Prey Interaction

Ecology and Evolution, Volume 16, Issue 4, April 2026.
(A) The predator Phytoseiulus persimilis and its prey Tetranychus urticae were reared under mild or extreme heat waves from egg to adulthood, which resulted in asymmetrical thermal shifts of adult body sizes in favour of prey under extreme heat waves. (B) Single couples of adult predators and prey, reared under mild heat waves interacted at mild heat ...
Andreas Walzer, Bernhard Spangl, Lina Weissengruber, Gösta Nachman, Thomas Tscholl   +4 more
wiley   +1 more source

A Review on Ginkgo biloba: Nutritional Profile, Toxicity, and Its Therapeutic Potential in Stroke Management

eFood, Volume 7, Issue 1, February 2026.
Stroke is a neurological impairment caused by vascular injury of the central nervous system, and globally, stroke is ranked as the second most common cause of death and disability. Numerous risk factors, disease processes, and mechanisms can contribute to stroke, which is not a single disease. G.
Ali Ikram, Farhang Hameed Awlqadr, Hamna Tayyab, Mamoona Shehzadi, Muhammad Tayyab Arshad, Md. Sakhawot Hossain, Ahmadullah Zahir   +6 more
wiley   +1 more source

An Anti-serum for Scorpion Venom [PDF]

Journal of Hygiene, 1909
Many deaths occur every year in Egypt as the result of scorpion sting. These deaths are practically confined to Cairo and Upper Egypt, and are almost entirely among children. Unfortunately, owing to local conditions, it is almost impossible to obtain really accurate figures for this mortality, but some idea may be formed from the statistics given below
openaire   +2 more sources