Results 61 to 70 of about 5,188 (174)

Short Peptides from Asian Scorpions: Bioactive Molecules with Promising Therapeutic Potential

Toxins
Scorpion venom peptides, particularly those derived from Asian species, have garnered significant attention, offering therapeutic potential in pain management, cancer, anticoagulation, and infectious diseases.
Kaiyun Xin, Ruize Sun, Wanyang Xiao, Weijie Lu, Chenhui Sun, Jietao Lou, Yanyan Xu, Tianbao Chen, Di Wu, Yitian Gao   +9 more
doaj   +1 more source

Scorpion Venom Causes Apoptosis by Increasing Reactive Oxygen Species and Cell Cycle Arrest in MDA-MB-231 and HCT-8 Cancer Cell Lines

Journal of Evidence-Based Integrative Medicine, 2018
Objectives. The objective of this study was to examine the effect of scorpion venoms on cancer cell progression, apoptosis, and cell cycle arrest. Scorpion venoms are known to possess numerous bioactive compounds that act against cancer progression by ...
Abdulrahman Khazim Al-Asmari PhD, Anvarbatcha Riyasdeen PhD, Mozaffarul Islam PhD   +2 more
doaj   +1 more source

Exon Shuffling and Origin of Scorpion Venom Biodiversity

Toxins, 2016
Scorpion venom is a complex combinatorial library of peptides and proteins with multiple biological functions. A combination of transcriptomic and proteomic techniques has revealed its enormous molecular diversity, as identified by the presence of a ...
Xueli Wang, Bin Gao, Shunyi Zhu
doaj   +1 more source

Time‐calibrated relationships of a rare cave catfish (Trichomycterus rubbioli): Shedding light on troglobitic lifestyle origin in the Brazilian caatinga

Journal of Fish Biology, Volume 109, Issue 1, Page 362-370, July 2026.
Abstract Catfishes of the subfamily Trichomycterinae comprise the most diverse fish group with species adapted to live in Neotropical caves, but past evolutionary scenarios that have driven the origin of these troglobitic species remain unknown. We herein investigate the phylogenetic position of the cave‐restricted Trichomycterus rubbioli, endemic to ...
Wilson J. E. M. Costa, Paulo J. Vilardo, José Leonardo O. Mattos, Axel M. Katz, Valter M. Azevedo‐Santos, Pedro L. C. Uzeda, Rodrigo L. Ferreira   +6 more
wiley   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, Volume 20, Issue 6, Page 1398-1419, June 2026.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

Isolation and Characterization of Insecticidal Toxins from the Venom of the North African Scorpion, Buthacus leptochelys

Toxins, 2019
Various bioactive peptides have been identified in scorpion venom, but there are many scorpion species whose venom has not been investigated. In this study, we characterized venom components of the North African scorpion, Buthacus leptochelys, by mass ...
Yusuke Yoshimoto, Masahiro Miyashita, Mohammed Abdel-Wahab, Moustafa Sarhan, Yoshiaki Nakagawa, Hisashi Miyagawa   +5 more
doaj   +1 more source

Exploring Floristic Diversity and Medicinal Plant Uses in Venda, Limpopo, South Africa

Feddes Repertorium, Volume 137, Issue 2, June 2026.
ABSTRACT Plants have been an important source of medicine for thousands of years. To better understand the current diversity and usage of medicinal plants, floristic studies are essential. This report documents an expedition conducted in the Venda region of Limpopo, South Africa. The study was carried out in Shanzha and surrounding villages, as well as
Gurusamy Manikandan, Iliassou L. Mouafon, David R. Katerere   +2 more
wiley   +1 more source

Partial purification of peptides present in the Tityus macrochirus (Buthidae) scorpion venom and preliminary assessment of their cytotoxicity

Biomédica: revista del Instituto Nacional de Salud, 2017
Introduction: Scorpion venom contains peptides with neurotoxic action primarily active on ion channels in the nervous system of insects and mammals. They are also characterized as cytolytic and anticancer, biological characteristics that have not yet ...
Clara Andrea Rincón-Cortés, Edgar Antonio Reyes-Montaño, Nohora Angélica Vega-Castro   +2 more
doaj   +1 more source

Anticancer Peptides Derived from the Venom of Scorpions Inhabiting Various Biotopes [PDF]

Catrina: The International Journal of Environmental Sciences
Despite advances in surgical techniques and adjuvant therapies, the relative prevalence rate of all cancers has risen sharply over the last three decades.
Mariam Gerges, Amir Mehana, Tarek Rahmy, Mohamed Abdel-Rahman   +3 more
doaj   +1 more source

The action of red scorpion (Mesobuthus tamulus coconsis, pocock) venom and its isolated protein fractions on blood sodium levels

Journal of Venomous Animals and Toxins including Tropical Diseases, 2007
Red scorpion (Mesobuthus tamulus or Buthus tamulus) venom samples were collected at different regions of India: western (Chiplun and Ahmednagar from Maharashtra State) and southern (Ratnagiri and Chennai from Tamil Nadu State). The action of whole venoms
R. V. Badhe, A. B. Thomas, A. D. Deshpande, N. Salvi, A. Waghmare   +4 more
doaj   +1 more source