Results 101 to 110 of about 556,612 (159)

The First K⁺-Channel Blocker Described from Tityus fasciolatus Venom: The Purification, Molecular Cloning, and Functional Characterization of α-KTx4.9 (Tf5)

Toxins
Hundreds of toxins, particularly from scorpions of lesser medical significance, remain unknown, especially those from species endemic to specific ecosystems, such as Tityus fasciolatus. Their discovery could contribute to the development of new drugs for
Isolda de Sousa Monteiro, Israel Flor Silva de Araújo, Thalita Soares Camargos, Ernesto Ortiz, Adolfo Carlos Barros de Souza, Jonathan Dias Lima, Lourival D. Possani, Elisabeth Ferroni Schwartz, Diogo Vieira Tibery   +8 more
doaj   +1 more source

An Alkaloid from Scorpion Venom: Chemical Structure and Synthesis

, 2018
While most scorpion venom components identified in the past are peptidic or proteinic in nature, we report here a new alkaloid isolated from the venom of the Mexican scorpion Megacormus gertschi.
Fernando Zamudio Zuñiga (5540780), Richard N. Zare (631413), Elumalai Gnanamani, Lourival Domingos Possani (5540786), Shibdas Banerjee, Elumalai Gnanamani (4672006), Stephen R. Lynch, Richard N. Zare, Stephen R. Lynch (2044711), Shibdas Banerjee (2036431), Juana María Jiménez-Vargas (5540783), Lourival Domingos Possani, Fernando Zamudio Zuñiga, Juana María Jiménez-Vargas   +13 more
core   +1 more source

Immunological characterization of a non-toxic peptide conferring protection against the toxic fraction (AahG50) of the Androctonus australis hector venom.

, 2008
KAaH1 and KAaH2 are non-toxic peptides, isolated from the venom of the Androctonus australis hector (Aah) scorpion. In a previous study, we showed these peptides to be the most abundant (approximately 10% each) in the toxic fraction (AahG50) of the Aah ...
El Ayeb, Mohamed, Mlayah-Bellalouna, Saoussen, Sampieri, François, Srairi-Abid, Najet, Kaabi, Hajer, Mejri, Thouraya   +5 more
core   +1 more source

Development of a gold nanoparticle-based novel diagnostic prototype for in vivo detection of Indian red scorpion (Mesobuthus tamulus) venom

Toxicon: X
Indian red scorpion Mesobuthus tamulus is responsible for substantial mortality in India and Sri Lanka; however, no specific diagnostic method is available to detect the venom of this scorpion in envenomed plasma or body fluid.
Upasana Puzari, Mojibur R. Khan, Ashis K. Mukherjee   +2 more
doaj   +1 more source

Investigation of in vivo potential of scorpion venom against skin tumorigenesis in mice via targeting markers associated with cancer development

, 2016
Abdulrahman K Al Asmari, Abdul Quaiyoom Khan Research Centre, Prince Sultan Military Medical City, Riyadh, Saudi Arabia Abstract: Cancer is the leading cause of morbidity and mortality all over the world in spite of the advances made in its management.
Khan AQ, Al Asmari AK
core  

Extraction and quantification of antivenomous antibodies in chicken eggs against scorpion venom

: Avian-derived IgY is thought to be the best therapy for scorpion bites concerning low-level side effects. The present study analyzed a hypothesis about the neutralization of scorpion venom Androcotonus australis through antibodies produced in the egg ...
Mehvish Andleeb (16561553), Aleem Ahmed Khan (5066171)   +1 more
core   +1 more source

Structural determinants of the scorpion venom peptide Uy234 govern bactericidal activity and membrane-disruptive properties. [PDF]

Front Microbiol
Villa-Merlan AK, Mescola A, Fong-Coronado PA, Juárez González VR, Fernández-Sánchez F, Alessandrini A, Balleza D, Quintero-Hernández V.   +7 more
europepmc   +1 more source

Inhibition of Chikungunya virus nsP2 protease in vitro by scorpion venom peptide pantinin-1. [PDF]

PLoS One
Mastalipour M, Coronado MA, Hernández González JE, Willbold D, Eberle RJ.   +4 more
europepmc   +1 more source

The underlying mechanism of scorpion venom peptide BmK AS in reducing epilepsy seizures: mediated through dual modulation of Nav1.6 and the inflammasome pathway. [PDF]

Front Pharmacol
Zhao L, Wang C, Qi D, Sun M, Qi H, Dong Y, Zeng Y, Tang L, Ding J, Zhu Y, Xiao Q, Wu W, Ji Y, Tao J.   +13 more
europepmc   +1 more source

Correction: Antibacterial Activity and Mechanism of a Scorpion Venom Peptide Derivative In Vitro and In Vivo. [PDF]

PLoS One
Cao L, Dai C, Li Z, Fan Z, Song Y, Wu Y, Cao Z, Li W.   +7 more
europepmc   +1 more source