Results 81 to 90 of about 556,612 (159)

Unveiling the Evolutionary History of European Vipers and Their Venoms From a Multi‐Omic Approach

Molecular Ecology, Volume 34, Issue 21, November 2025.
ABSTRACT Snake genomes attract significant attention from multiple disciplines, including medicine, drug bioprospection, and evolutionary biology. However, genomic research within the Viperidae family has mostly focused on the subfamily Crotalinae, while the true vipers (Viperinae) have largely been overlooked.
Adrián Talavera, Marc Palmada‐Flores, Fernando Martínez‐Freiría, Gabriel Mochales‐Riaño, Bernat Burriel‐Carranza, Maria Estarellas, Daniel Fernández‐Guiberteau, Álvaro Camina, Sylvain Ursenbacher, Judit Vörös, Bálint Halpern, Davinia Pla, Juan José Calvete, Alexander S. Mikheyev, Tomàs Marquès‐Bonet, Salvador Carranza   +15 more
wiley   +1 more source

Cn29, a novel orphan peptide found in the venom of the scorpion Centruroides noxius: Structure and function

, 2019
International audienceA peptide (Cn29) from the venom of the scorpion Centruroides noxius (about 2% of the soluble venom) was purified and its primary and three-dimensional structures were determined.
Mendoza, R.L.L., Possani, L.D., Cid-Uribe, J.I., Gurrola, G.B., Delepierre, M., Coronas, F.V., Guijarro, J.I.   +6 more
core   +1 more source

Potassium channel blockers from the venom of the Brazilian scorpion Tityus serrulatus (Lutz and Mello, 1922)

, 2016
International audiencePotassium (K(+)) channels are trans-membrane proteins, which play a key role in cellular excitability and signal transduction pathways.
Pimenta, Adriano, Bougis, Pierre, Pimenta, Adriano M.C., Martin-Eauclaire, Marie-France, de Lima, Maria-Elena   +4 more
core   +1 more source

Pharmacological and therapeutic applications of scorpion venom peptides: A Review [PDF]

Introduction: In recent years, scorpion venom and its peptide compounds have attracted growing scientific interest. A remarkable biological diversity and strong therapeutic potential characterize these compounds.
Abdessamad, Elmourid, KHADRA, Ahmed, BOUIMEJA, Btissam, Namiq, Siham, TOULOUN, Oulaid   +4 more
core   +1 more source

Tamulustoxin: a novel potassium channel blocker from the venom of the Indian red scorpion mesobuthus tamulus

, 2000
We have characterized tamulustoxin, a novel 35-amino-acid peptide found in the venom of the Indian red scorpion (Mesobuthus tamulus). Tamulustoxin was identified through a [125I]toxin I screen, designed to identify toxins that block voltage-activated ...
Clark, G. S., Owen, D. G., Gopalakrishnakone, P., Strong, P. N., Deshpande, J. M., De-Allie, F. A., Joseph, J. S., Jeyaseelan, K., Gadre, S. V., Yemul, V., Kini, R. M., Armugam, A., Kamat, R.   +12 more
core   +1 more source

CHARACTERIZATION OF NANO-ASSEMBLIES DERIVED FROM SCORPION VENOM, CONJUGATED WITH CHITOSAN NANOPARTICLES AND GAMMA-IRRADIATED VENOM BY TEM AND PROTEIN ANALYSIS [PDF]

Journal of the Egyptian Society of Parasitology
Leiurus quinquestriatus scorpion venom is a rich source of bioactive peptides with significant biomedical therapies, particularly in cancer. This study evaluated structural, biochemical, nan- oscale, and biological properties of venom; native, gamma ...
ABIR EL-FIKY, NOURAN KHATAB, GEHAN SAFWAT   +2 more
doaj   +1 more source

Scorpion venom peptide HsTx2 suppressed PTZ-induced seizures in mice via the circ_0001293/miR-8114/TGF-β2 axis. [PDF]

J Neuroinflammation, 2022
Hu Y, Meng B, Yin S, Yang M, Li Y, Liu N, Li S, Liu Y, Sun D, Wang S, Wang Y, Fu Z, Wu Y, Pang A, Sun J, Wang Y, Yang X.   +16 more
europepmc   +1 more source

SVHRSP protects against rotenone-induced neurodegeneration in mice by inhibiting TLR4/NF-κB-mediated neuroinflammation via gut microbiota

npj Parkinson's Disease
Strong evidence indicates that remodeling gut microbiota may be an effective approach to combat Parkinson’s disease (PD). Scorpion Venom Heat-Resistant Synthesized Peptide (SVHRSP), a synthesized peptide discovered from scorpion venom, displays potent ...
Mengdi Chen, Yu Zhang, Liyan Hou, Zirui Zhao, Peiyan Tang, Qingquan Sun, Jie Zhao, Qingshan Wang   +7 more
doaj   +1 more source

Smp24, a Scorpion-Venom Peptide, Exhibits Potent Antitumor Effects against Hepatoma HepG2 Cells via Multi-Mechanisms In Vivo and In Vitro. [PDF]

Toxins (Basel), 2022
Nguyen T, Guo R, Chai J, Wu J, Liu J, Chen X, Abdel-Rahman MA, Xia H, Xu X.   +8 more
europepmc   +1 more source

Correlation of Venom Toxinome Composition of Indian Red Scorpion (Mesobuthus tamulus) with Clinical Manifestations of Scorpion Stings: Failure of Commercial Antivenom to Immune-Recognize the Abundance of Low Molecular Mass Toxins of This Venom

, 2020
The Indian red scorpion (Mesobuthus tamulus), with its life-threatening sting, is the world’s most dangerous species of scorpion. The toxinome composition of M. tamulus venom was determined by tandem mass spectrometry (MS) analysis of venom protein bands
Ashis Kumar Mukherjee, Bhabana Das (8565321), Bhabana Das, Aparup Patra, Aparup Patra (3394091), Ashis Kumar Mukherjee (8565324)   +5 more
core   +1 more source