Results 81 to 90 of about 3,122 (171)

Smp24, a Scorpion-Venom Peptide, Exhibits Potent Antitumor Effects against Hepatoma HepG2 Cells via Multi-Mechanisms In Vivo and In Vitro. [PDF]

Toxins (Basel), 2022
Nguyen T, Guo R, Chai J, Wu J, Liu J, Chen X, Abdel-Rahman MA, Xia H, Xu X.   +8 more
europepmc   +1 more source

Scorpion Venom Peptide Effects on Inhibiting Proliferation and Inducing Apoptosis in Canine Mammary Gland Tumor Cell Lines. [PDF]

Animals (Basel), 2021
Panja K, Buranapraditkun S, Roytrakul S, Kovitvadhi A, Lertwatcharasarakul P, Nakagawa T, Limmanont C, Jaroensong T.   +7 more
europepmc   +1 more source

Characterization of Leiurus abdullahbayrami (Scorpiones: Buthidae) venom: peptide profile, cytotoxicity and antimicrobial activity

Journal of Venomous Animals and Toxins including Tropical Diseases, 2014
Background Scorpion venoms are rich bioactive peptide libraries that offer promising molecules that may lead to the discovery and development of new drugs.Leiurus abdullahbayrami produces one of the most potent venoms among Turkish scorpions that ...
Efe Erdeş, Tuğba Somay Doğan, İlhan Coşar, Tarık Danışman, Kadir Boğaç Kunt, Tamay Şeker, Meral Yücel, Can Özen   +7 more
doaj   +1 more source

The First K⁺-Channel Blocker Described from Tityus fasciolatus Venom: The Purification, Molecular Cloning, and Functional Characterization of α-KTx4.9 (Tf5)

Toxins
Hundreds of toxins, particularly from scorpions of lesser medical significance, remain unknown, especially those from species endemic to specific ecosystems, such as Tityus fasciolatus. Their discovery could contribute to the development of new drugs for
Isolda de Sousa Monteiro, Israel Flor Silva de Araújo, Thalita Soares Camargos, Ernesto Ortiz, Adolfo Carlos Barros de Souza, Jonathan Dias Lima, Lourival D. Possani, Elisabeth Ferroni Schwartz, Diogo Vieira Tibery   +8 more
doaj   +1 more source

Development of a gold nanoparticle-based novel diagnostic prototype for in vivo detection of Indian red scorpion (Mesobuthus tamulus) venom

Toxicon: X
Indian red scorpion Mesobuthus tamulus is responsible for substantial mortality in India and Sri Lanka; however, no specific diagnostic method is available to detect the venom of this scorpion in envenomed plasma or body fluid.
Upasana Puzari, Mojibur R. Khan, Ashis K. Mukherjee   +2 more
doaj   +1 more source

Scorpion Venom Heat-Resistant Synthetic Peptide Alleviates DSS-Induced Colitis via α7nAChR-Mediated Modulation of the JAK2/STAT3 Pathway

Antioxidants
Background: Inflammatory bowel disease (IBD) is a chronic relapsing inflammatory disorder with limited treatment options. Emerging evidence reveals bidirectional crosstalk between gut and brain through inflammatory signaling, leading us to hypothesize ...
Kang Cheng, Guangbo He, Xiaxia Li, Yuqian Li, Xiaolin Cui, Xuefei Wu, Jau-Shyong Hong, Jie Zhao, Sheng Li, Yanjie Guo   +9 more
doaj   +1 more source

Mass spectrometric analysis of Odonthobuthus Doriae scorpion venom and its non-neutralized fractions after interaction with commercial antivenom

Scientific Reports
It is believed that antivenoms play a crucial role in neutralizing venoms. However, uncontrolled clinical effects appear in patients stung by scorpions after the injection of antivenom.
Adel Abdollahnia, Kiumars Bahmani, Atousa Aliahmadi, Mohammad Ali As’habi, Alireza Ghassempour   +4 more
doaj   +1 more source

A scorpion venom peptide Ev37 restricts viral late entry by alkalizing acidic organelles. [PDF]

J Biol Chem, 2019
Li F, Lang Y, Ji Z, Xia Z, Han Y, Cheng Y, Liu G, Sun F, Zhao Y, Gao M, Chen Z, Wu Y, Li W, Cao Z.   +13 more
europepmc   +1 more source

The Scorpion Venom Peptide Smp76 Inhibits Viral Infection by Regulating Type-I Interferon Response. [PDF]

Virol Sin, 2018
Ji Z, Li F, Xia Z, Guo X, Gao M, Sun F, Cheng Y, Wu Y, Li W, Ali SA, Cao Z.   +10 more
europepmc   +1 more source

Inhibition of Chikungunya virus nsP2 protease in vitro by scorpion venom peptide pantinin-1. [PDF]

PLoS One
Mastalipour M, Coronado MA, Hernández González JE, Willbold D, Eberle RJ.   +4 more
europepmc   +1 more source