Results 141 to 150 of about 2,790 (169)
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Scorpion Venom Peptides Accelerate Hematopoietic Recovery of Myelosuppression in Irradiated Mice
The American Journal of Chinese Medicine, 2009Sublethally irradiated mice were administered with scorpion venom peptides (SVP) or with PBS in the saline control group, 3 days before and 7 consecutive days after irradiation. Hematopoietic recovery was assessed by bone marrow (BM) cell proliferation index (PI) and colony forming unit-granulocyte/macrophage (CFU-GM), spleen weight index (SI) and ...
Weihua, Dong +3 more
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Peptides, 2003
BmTXKbeta, a scorpion toxin isolated from the Chinese scorpion Buthus martensii Karsch (BmK), was expressed as a GST fusion protein in BL21 (DE3) strain. The recombinant GST-BmTXKbeta protein was purified by affinity chromatography. When treated with enterokinase, the GST-BmTXKbeta fusion protein released an approximate 6.5kDa protein which was the ...
Zhijian, Cao +8 more
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BmTXKbeta, a scorpion toxin isolated from the Chinese scorpion Buthus martensii Karsch (BmK), was expressed as a GST fusion protein in BL21 (DE3) strain. The recombinant GST-BmTXKbeta protein was purified by affinity chromatography. When treated with enterokinase, the GST-BmTXKbeta fusion protein released an approximate 6.5kDa protein which was the ...
Zhijian, Cao +8 more
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Synthesis, antimicrobial activity and toxicity of analogs of the scorpion venom BmKn peptides
Toxicon, 2015Two analogs of the natural peptide BmKn1 and four of BmKn2 found in the venom of the scorpion Buthus martensii Karsh have been synthesized and tested to compare their antimicrobial and hemolytic activity with the natural ones. Modifications of the natural sequence were done on the hydrophobic side of the alpha helix by increasing the size and ...
Roberto de la Salud, Bea +2 more
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Meucin-49, a multifunctional scorpion venom peptide with bactericidal synergy with neurotoxins
Amino Acids, 2018Besides key roles in prey capture and predator defense, scorpion venom also functions as internal immune agents protecting the venom gland from infection and external immune agents cleaning saprophytic microbes from their own body surfaces. However, antimicrobials (typically antimicrobial peptides, AMPs) in the venom often exist in low abundance that ...
Bin, Gao +3 more
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Chlorotoxin and related peptides: Short insect toxins from scorpion venom
Russian Journal of Bioorganic Chemistry, 2014Scorpion venom is a complex multicomponent mixture of biologically active substances, some of which possess very interesting properties and are used in quite unexpected fields. The family of chlorotoxin (CTX)-like peptides serves a good example. These toxins exhibit insecticidal activity, however, their molecular mechanism of action on insect organism ...
A A, Arzamasov +2 more
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Antimicrobial and Antibiofilm Activity of Mauriporin, a Multifunctional Scorpion Venom Peptide
International Journal of Peptide Research and Therapeutics, 2014Many pathogenic free living and biofilm forming bacterial organisms can cause serious infections to humans that could consequently have devastating effects on human health. A significant number of these microbial organisms are resistant to almost all known conventional antibiotics and the ability of some these strains to form sessile communities of ...
Ammar Almaaytah +4 more
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Therapeutic effect and potential application of scorpion venom peptide
Theoretical and Natural ScienceScorpions has been existing on earth for hundreds of million years, and its venoms are mostly highly toxic and presents a deadly threat to people around the world. Scorpion venoms are highly complicated cocktails of bioactive components including proteins, amino acids, peptides, and other organic or inorganic molecules.
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Antithrombotic and thrombolytic effects of scorpion venom peptides
Toxicon, 1997X. Lu, L. Bai, Y. Song, Q. Zhu, Q. Hou
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