Results 61 to 70 of about 2,790 (169)

The effect of lysine substitutions in the biological activities of the scorpion venom peptide VmCT1

European Journal of Pharmaceutical Sciences, 2019
Antimicrobial peptides (AMPs) are biologically active molecules with a broad-spectrum activity against a myriad of microorganisms. Aside from their antimicrobial functions, AMPs present physicochemical and structural properties that allow them to exert activity against other kind of cells, such as cancer cells.
Cibele Nicolaski, Pedron, Cyntia Silva, de Oliveira, Adriana Farias, da Silva, Gislaine Patricia, Andrade, Maria Aparecida, da Silva Pinhal, Giselle, Cerchiaro, Pedro Ismael, da Silva Junior, Fernanda Dias, da Silva, Marcelo Der Torossian, Torres, Vani Xavier, Oliveira   +9 more
openaire   +2 more sources

Evolution of Phospholipase A2 in Bees and Flies

Ecology and Evolution, Volume 15, Issue 10, October 2025.
This study investigated the evolution of the PLA2 gene in bees and flies and compared the evolutionary rate between them, which denotes the toxic group and the non‐toxic group. The results showed that PLA2 was under purifying selection and that an accelerated evolution of PLA2 occurred in the toxic group when compared with the non‐toxic group ...
Siqi Yang, Minyu Wu, Ping Feng
wiley   +1 more source

Molecular Characterization of a cDNA Encoding of an Anionic Cysteine-Free Antimicrobial Peptide From the Iranian Scorpion Odontobuthus Doriae Venom Glands

Pharmaceutical and Biomedical Research, 2022
Background: The venom peptides from the scorpion fauna of Iran have been poorly characterized so far. Objectives: In this study, we identified a cDNA encoding of an anionic cysteine-free antimicrobial peptide from the Iranian yellow scorpion odontobuthus
Amir Jalali, Masoud Mahdavinia, Hamid Galehdari, Masoumeh Baradaran, Davood Valdi-Biranvand, Maryam Naderi Soorki   +5 more
doaj  

Venom Gland Transcriptomic and Proteomic Analyses of the Enigmatic Scorpion Superstitionia donensis (Scorpiones: Superstitioniidae), with Insights on the Evolution of Its Venom Components

Toxins, 2016
Venom gland transcriptomic and proteomic analyses have improved our knowledge on the diversity of the heterogeneous components present in scorpion venoms. However, most of these studies have focused on species from the family Buthidae.
Carlos E. Santibáñez-López, Jimena I. Cid-Uribe, Cesar V. F. Batista, Ernesto Ortiz, Lourival D. Possani   +4 more
doaj   +1 more source

A Conceptual Review of Naturally Occurring Toxins and Venoms as Peptide Blockers to Combat Chronic Low Back Pain

JOR SPINE, Volume 8, Issue 3, September 2025.
This review explores the therapeutic potential of naturally occurring venom‐derived peptides, particularly from reptiles and insects, as novel calcium channel blockers for managing chronic low back pain caused by intervertebral disc degeneration.
James Melrose, Stone Sima, Neha Chopra, Ashish Diwan, Zi Gu   +4 more
wiley   +1 more source

The Cuban scorpion Rhopalurus junceus (Scorpiones, Buthidae): component variations in venom samples collected in different geographical areas

Journal of Venomous Animals and Toxins including Tropical Diseases, 2013
Backgound The venom of the Cuban scorpion Rhopalurus junceus is poorly study from the point of view of their components at molecular level and the functions associated.
Rodolfo Rodríguez-Ravelo, Fredy I V Coronas, Fernando Z Zamudio, Lidia González-Morales, Georgina Espinosa López, Ariel Ruiz Urquiola, Lourival D Possani   +6 more
doaj   +1 more source

An Up‐to‐Date Review of Traditional Chinese Medicine in the Treatment of Atherosclerosis: Components, Mechanisms, and Therapeutic Potentials

Phytotherapy Research, Volume 39, Issue 8, Page 3709-3735, August 2025.
Traditional Chinese medicine in atherosclerosis: multi‐target modulation of pathogenesis. ABSTRACT Atherosclerosis is a chronic inflammatory disease and a major global health concern. In recent years, traditional Chinese medicines (TCMs) have demonstrated multi‐target therapeutic potential against atherosclerosis by modulating inflammatory responses ...
Dilaram Nijat, Qingzhe Zhao, Gulhasal Abdurixit, Jianhua He, Haipeng Liu, Jinyao Li   +5 more
wiley   +1 more source

Short-Chained Linear Scorpion Peptides: A Pool for Novel Antimicrobials

Antibiotics
Scorpion venom peptides are generally classified into two main groups: the disulfide bridged peptides (DBPs), which usually target membrane-associated ion channels, and the non-disulfide bridged peptides (NDBPs), a smaller group with multifunctional ...
Tolis Panayi, Spiridoula Diavoli, Vicky Nicolaidou, Christos Papaneophytou, Christos Petrou, Yiannis Sarigiannis   +5 more
doaj   +1 more source

Discovery of a Novel Insecticidal Peptide with a Cystine-Stabilized α-Helix/α-Helix Motif from the Venom of Scorpion Liocheles australasiae

Molecules
Scorpion venom contains various bioactive peptides, many of which exhibit insecticidal activity. The majority of these peptides have a cystine-stabilized α-helix/β-sheet (CSαβ) motif. In addition to these peptides, scorpion venom also contains those with
Masahiro Miyashita, Naoya Mitani, Fuki Iwamoto, Mitsuki Hirota, Yoshiaki Nakagawa   +4 more
doaj   +1 more source

First transcriptome analysis of the venom glands of the scorpion Hottentotta zagrosensis (Scorpions: Buthidae) with focus on venom lipolysis activating peptides

Frontiers in Pharmacology
IntroductionScorpion venom is a rich source of biological active peptides and proteins. Transcriptome analysis of the venom gland provides detailed insights about peptide and protein venom components. Following the transcriptome analysis of different species in our previous studies, our research team has focused on the Hottentotta zagrosensis as one of
Fatemeh Salabi, Hedieh Jafari, Masoud Mahdavinia, Reza Azadnasab, Saeedeh Shariati, Saeedeh Shariati, Mahsa Lari Baghal, Majid Tebianian, Masoumeh Baradaran   +8 more
openaire   +3 more sources