Results 41 to 50 of about 356,030 (194)

Scorpion Venom as a Source of Antimicrobial Peptides: Overview of Biomolecule Separation, Analysis and Characterization Methods

, 2023
Scorpion venoms have long captivated scientific researchers, primarily due to the potency and specificity of the mechanism of action of their derived components. Among other molecules, these venoms contain highly active compounds, including antimicrobial
Jean-Marc Sabatier, Sahyoun, Christina, Sara Nasr, Christina Sahyoun, Ziad Fajloun, Roufayel, Rabih, Fajloun, Ziad, Christian Legros, Adolfo Borges, Sabatier, Jean-Marc, Rabih Roufayel, Riad Nasr, Nasr, Sara, Nasr, Riad, Legros, Christian, Borges, Adolfo   +15 more
core   +1 more source

EFFECT OF BEE AND SCORPION VENOMS ON PROSTATE CANCER IN VITRO STUDY [PDF]

Journal of the Egyptian Society of Parasitology, 2019
Prostate cancer (PCa) is the commonest diagnosed visceral malignancy among males worldwide. Recent studies have shown that bee venom target the cancer cells without effect on the normal cells by activating PC3 with oxidative substances against prostate ...
ABDELRAHMAN BAYOUMI, HAZEM KHALIL, KHADEGA AMINE, ABIR ELFIKY   +3 more
doaj   +1 more source

Anticancer Peptides Derived from the Venom of Scorpions Inhabiting Various Biotopes [PDF]

Catrina: The International Journal of Environmental Sciences
Despite advances in surgical techniques and adjuvant therapies, the relative prevalence rate of all cancers has risen sharply over the last three decades.
Mariam Gerges, Amir Mehana, Tarek Rahmy, Mohamed Abdel-Rahman   +3 more
doaj   +1 more source

Antinociceptive, antiinflammatory, and antipyretic effects induced by the venom of Egyptian scorpion Androctonus amoreuxi

Journal of Basic and Applied Zoology, 2020
Background Scorpion venom is a very complicated mixture of various peptides/proteins which could induce toxicological and pharmacological responses.
Nahla M. Shoukry, Mohamed L. Salem, Wafaa K. Teleb, Mohamed M. Abdel Daim, Mohamed A. Abdel-Rahman   +4 more
doaj   +1 more source

Bradykinin-Potentiating Factors of Venom from Iranian Medically Important Scorpions [PDF]

Archives of Razi Institute, 2019
The venom of animals, including snakes, scorpions, and spiders is a complex combination of proteins, peptides, and other biomolecules as well as some minerals.
H. R. Goudarzi, Z. Salehi Najafabadi, A. Movahedi, M. Noofeli   +3 more
doaj   +1 more source

BotCl, the First Chlorotoxin-like Peptide Inhibiting Newcastle Disease Virus: The Emergence of a New Scorpion Venom AMPs Family

Molecules, 2023
Newcastle disease virus (NDV) is one of the most serious contagions affecting domestic poultry and other avian species. It causes high morbidity and mortality, resulting in huge economic losses to the poultry industry worldwide.
Abir Jlassi, Marwa Mekni-Toujani, Asma Ferchichi, Charfeddine Gharsallah, Christian Malosse, Julia Chamot-Rooke, Mohamed ElAyeb, Abdeljelil Ghram, Najet Srairi-Abid, Salma Daoud   +9 more
doaj   +1 more source

Evolution Stings: The Origin and Diversification of Scorpion Toxin Peptide Scaffolds

Toxins, 2013
The episodic nature of natural selection and the accumulation of extreme sequence divergence in venom-encoding genes over long periods of evolutionary time can obscure the signature of positive Darwinian selection.
Kartik Sunagar, Eivind A. B. Undheim, Angelo H. C. Chan, Ivan Koludarov, Sergio A. Muñoz-Gómez, Agostinho Antunes, Bryan G. Fry   +6 more
doaj   +1 more source

Pleiotropic Anticancer Properties of Scorpion Venom Peptides: Rhopalurus princeps Venom as an Anticancer Agent.

Drug design, development and therapy, 2020
To date, the success of conventional chemotherapy, radiotherapy, and targeted biological therapies in cancer treatment is not satisfactory. The main reasons for such outcomes rely on low target selectivity, primarily in chemo- and radiotherapy, ineffectiveness to metastatic disease, drug resistance, and severe side effects.
Mikaelian,Arthur G, Traboulay,Eric, Zhang,Xiaofei Michael, Yeritsyan,Emma, Pedersen,Peter L., Ko,Young Hee, Matalka,Khalid Z   +6 more
openaire   +5 more sources

Short-chain peptides identification of scorpion Buthus martensi Karsch venom by employing high orthogonal 2D-HPLC system and tandem mass spectrometry

, 2012
Scorpion venom contains a considerable variety of neurotoxic peptides that can act on ionic channels. Here, we describe an orthogonal 2D-reversed phase/hydrophilic interaction chromatography system (RPLC/HILIC) and use it to separate short-chain peptides
Xue, Xingya, Yu, Long, Yan, Jingyu, Liang, Xinmiao, Li, Xiuling, 梁鑫淼, Zhang, Xiuli, Guo, Zhimou, Xu, Junyan   +8 more
core   +1 more source

The Enzymatic Core of Scorpion Venoms

Toxins, 2022
Enzymes are an integral part of animal venoms. Unlike snakes, in which enzymes play a primary role in envenomation, in scorpions, their function appears to be ancillary in most species.
Gustavo Delgado-Prudencio, Jimena I. Cid-Uribe, J. Alejandro Morales, Lourival D. Possani, Ernesto Ortiz, Teresa Romero-Gutiérrez   +5 more
doaj   +1 more source