Results 21 to 30 of about 26,346 (266)
Prion Evolvability and the Hazard of Atypical Scrapie in Small Ruminants
Open Veterinary Science, 2020 Observations on strain behaviour and direct demonstrations of natural selection establish that the scrapie agent and prions in general are able to evolve.
Adams David B.
doaj +1 more source
Diagnosis in Scrapie: Conventional Methods and New Biomarkers
Pathogens, 2023 Scrapie, a naturally occurring prion disease affecting goats and sheep, comprises classical and atypical forms, with classical scrapie being the archetype of transmissible spongiform encephalopathies.
Diego Sola +12 more
doaj +1 more source
Iron and iron/manganese ratio in forage from Icelandic sheep farms: relation to scrapie
Acta Veterinaria Scandinavica, 2006 This study was undertaken in order to examine whether any connection existed between the amounts of iron in forage and the sporadic occurrence of scrapie observed in certain parts of Iceland.
Jóhannesson T +4 more
doaj +1 more source
Advanced survival models for risk-factor analysis in scrapie [PDF]
, 2007 Because of the confounding effects of long incubation duration and flock management, accurate epidemiological studies of scrapie outbreaks are difficult to carry out.
Andréoletti, Olivier +6 more
core +4 more sources
PLoS ONE, 2022 Nor98-like atypical scrapie is a sporadic disease that affects the central nervous system of sheep and goats that, in contrast to classical scrapie, is not generally regarded as naturally transmissible.
Robert B Piel +7 more
doaj +2 more sources
Synthesis and structural characterization of a mimetic membrane-anchored prion protein [PDF]
, 2006 During pathogenesis of transmissible spongiform encephalopathies (TSEs) an abnormal form (PrPSc) of the host encoded prion protein (PrPC) accumulates in insoluble fibrils and plaques. The two forms of PrP appear to have identical covalent structures, but
Andrew C. Gill +44 more
core +1 more source
TSE pathogenesis in cattle and sheep [PDF]
, 2008 Many studies have been undertaken in rodents to study the pathogenesis of transmissible spongiform encephalopathies (TSE). Only a few studies have focused on the pathogenesis of bovine spongiform encephalopathy (BSE) and scrapie in their natural hosts ...
Bossers, A. +2 more
core +3 more sources
BMC Veterinary Research, 2008 Background The development of active surveillance programmes for transmissible spongiform encephalopathies of small ruminants across Europe has led to the recent identification of a previously undetected form of ovine prion disease, 'atypical' scrapie ...
Calavas Didier +5 more
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High prevalence of scrapie in a dairy goat herd: tissue distribution of disease-associated PrP and effect of PRNP genotype and age [PDF]
, 2009 Following a severe outbreak of clinical scrapie in 2006–2007, a large dairy goat herd was culled and 200 animals were selected for post-mortem examinations in order to ascertain the prevalence of infection, the effect of age, breed and PRNP genotype on
Dawson, M. +13 more
core +3 more sources
Classical scrapie in small ruminants is caused by at least four different prion strains
Veterinary Research, 2021 The diversity of goat scrapie strains in Europe has recently been studied using bioassays in a wide collection of rodent models, resulting in the classification of classical scrapie into four different categories.
Alba Marín-Moreno +10 more
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