Results 21 to 30 of about 11,109 (115)

In Vivo Quantification of Creatine Kinase Kinetics in Mouse Brain Using 31P‐MRS at 7 T

open access: yesNMR in Biomedicine, Volume 38, Issue 6, June 2025.
We demonstrate the feasibility of using 31P‐MRS to quantify creatine kinase activity in the mouse brain on preclinical 7‐T scanners. A 20% drop in respiration increased the apparent forward rate constant by 36%, likely due to altered pH and mitochondrial ATP production.
Mohamed Tachrount   +3 more
wiley   +1 more source

Soil characteristics at artificial salt licks and their potential impacts on occurrence of chronic wasting disease

open access: yesEcosphere, Volume 16, Issue 3, March 2025.
Abstract Salt lick sites, where artificial salt blocks are placed at permanent locations, are common in summer grazing areas for free‐ranging sheep in Norwegian mountains. These areas often overlap with areas used by wild reindeer, and reindeer are frequently observed at these salt lick sites.
Line Tau Strand   +8 more
wiley   +1 more source

Guide to the structural characterization of protein aggregates and amyloid fibrils by CD spectroscopy

open access: yesProtein Science, Volume 34, Issue 3, March 2025.
Abstract Protein aggregation and amyloid formation are linked to numerous degenerative diseases, such as Alzheimer's or Parkinson's disease. Additionally, protein aggregation plays a crucial role in various biological processes, such as storage of molecules or cell signaling.
József Kardos   +10 more
wiley   +1 more source

Iatrogenic Cerebral Amyloid Angiopathy in Patients Treated With Cadaveric Dura Mater During Childhood Neurosurgery: A Retrospective Cohort Study

open access: yesEuropean Journal of Neurology, Volume 32, Issue 3, March 2025.
ABSTRACT Background Iatrogenic cerebral amyloid angiopathy (iCAA) is a recently identified clinico‐neuroradiological syndrome associated with medical procedures, particularly neurosurgical treatments involving cadaveric dura mater (e.g., Lyodura). iCAA can manifest as intracerebral hemorrhages, focal seizures, and cognitive impairment, with the risk ...
Slaven Pikija   +11 more
wiley   +1 more source

Microbial amyloids in neurodegenerative amyloid diseases

open access: yesThe FEBS Journal, Volume 292, Issue 6, Page 1265-1281, March 2025.
Numerous microbes, including those indigenous to the human microbiome, produce amyloidogenic proteins. These proteins have critical functions in bacterial physiology and their lifestyles. Emerging evidence indicates that microbial amyloids also interact directly or indirectly with host‐derived amyloid proteins, such as those which underlie Parkinson's ...
Timothy Sampson
wiley   +1 more source

Limitations and Applications of Rodent Models in Tauopathy and Synucleinopathy Research

open access: yesJournal of Neurochemistry, Volume 169, Issue 3, March 2025.
The successful development of therapeutics depends upon the ability of preclinical models to recapitulate the target disease biology in human patients. To better support drug discovery efforts for neurodegenerative diseases, we collated information on the currently available rodent models of tauopathy and synucleinopathy.
Emma Szegvari   +2 more
wiley   +1 more source

Cultivated meat microbiological safety considerations and practices

open access: yesComprehensive Reviews in Food Science and Food Safety, Volume 24, Issue 1, January 2025.
Abstract Cultivated meat, produced using cell culture technology, is an alternative to conventional meat production that avoids the risks from enteric pathogens associated with animal slaughter and processing. Cultivated meat therefore has significant theoretical microbiological safety advantages, though limited information is available to validate ...
Dean Joel Powell   +3 more
wiley   +1 more source

Fish Sludge as Feed in Circular Bioproduction: Overview of Biological and Chemical Hazards in Fish Sludge and Their Potential Fate via Ingestion by Invertebrates

open access: yesReviews in Aquaculture, Volume 17, Issue 1, January 2025.
This review provides knowledge of the biosecurity risks of using fish sludge to produce novel feed ingredients from low‐trophic, extractive animal species in circular value chains. The review includes nutritional composition, sludge treatment practices, EU regulations, and the fate of microbial and chemical hazards contained in sludge till raw ...
Kristin S. Pettersen   +25 more
wiley   +1 more source

Microbes Saving Lives and Reducing Suffering

open access: yes
Microbial Biotechnology, Volume 18, Issue 1, January 2025.
Kenneth Timmis   +26 more
wiley   +1 more source

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