Results 211 to 220 of about 63,696 (276)

Micro‐Organ Chip Deciphers Tumor‐Derived G‐CSF as Remote Commander of Lung Pre‐Metastatic Niche via VEGFA‐KDR Cascade

Advanced Science, Volume 13, Issue 7, 3 February 2026.
Breast cancer reprograms the lung into a receptive pre‐metastatic niche via a novel G‐CSF–VEGFA–KDR signaling axis. Using a micro‐organ chip that enables contact‐independent coculture, this study uncovers how tumor‐secreted G‐CSF activates lung capillary KDR to drive angiogenesis and prime the soil for metastasis—without direct tumor contact.
Jingxin Zhang, Xiaoying Huang, Lingchuan Ma, Zixing Chen, Tianyao Li, Lijian Wang, Yutong Guo, Hu Xu, Junqi Li, Jiang‐Jiang Qin, Xiang Wang, Yuhong Cao, Kai Miao   +12 more
wiley   +1 more source

Reduced triacylglycerols and lipid droplets are associated with resilience to Alzheimer's disease

Alzheimer's &Dementia, Volume 22, Issue 2, February 2026.
Abstract INTRODUCTION Although it has become clear that alterations in lipid metabolism are associated with Alzheimer's disease (AD), it is unclear how they contribute to both cognitive decline and the pathophysiology of AD. METHODS Lipidomics and activity‐based protein profiling (ABPP) were performed in the frontal cortex of control, AD and resilient ...
Daan van der Vliet, Luuk E. de Vries, Xinyu Di, Dennis Wever, Brechtje de Jong, Marc T. C. van der Meij, Marielle van der Peet, Amy C. Harms, Thomas Hankemeier, Dick F. Swaab, Inge Huitinga, Joost Verhaagen, Mario van der Stelt   +12 more
wiley   +1 more source

SDF-1 Bound Heparin Nanoparticles Recruit Progenitor Cells for Their Differentiation and Promotion of Angiogenesis after Stroke. [PDF]

Adv Healthc Mater
Wilson KL, Joseph NI, Onweller LA, Anderson AR, Darling NJ, David-Bercholz J, Segura T.   +6 more
europepmc   +1 more source

Implantable Drug Delivery Systems for Skeletal Muscles and Eyes

Advanced NanoBiomed Research, Volume 6, Issue 2, February 2026.
This review highlights the different types of recent implantable drug delivery systems (IDDS) fabricated for a use with skeletal muscles, and with eyes. It presents the developments already made and the current research directions, showing the evolution of IDDS and their great diversity.
Serge Ostrovidov, Murugan Ramalingam, Hongkai Wu, Toshinori Fujie, Yukinari Nakamura, Takeshi Hori, Yuji Nashimoto, Xuetao Shi, Hirokazu Kaji   +8 more
wiley   +1 more source

Silencing of transient receptor potential canonical channel 4 inhibits endothelial progenitor cell angiogenesis by suppressing VEGF and SDF-1. [PDF]

Am J Transl Res
An X, Lu Y, Huang X.
europepmc   +1 more source

Chemical Profiling, In Silico and In Vitro Studies to Identify Potential CDK2 and mTOR Inhibitor From Selaginella inaequalifolia (Hook. & Grev.) Spring Ethanolic Extracts

Chemistry &Biodiversity, Volume 23, Issue 2, February 2026.
ABSTRACT The current study is aimed to reveal the phytoprofile of Selaginella inaequalifolia (Hook. & Grev.) Spring using GC–MS and predict the drug properties, toxicity, biological properties of S. inaequalifolia ethanolic extracts (SiEE) using in silico methods and in vitro toxicity assays, namely, MTT and BSLB assay.
Johnson Marimuthu Alias Antonysamy, Sivaraman Arumugam, Robin Charles Antony Arulraj, Anne Wincy Jacob Thomas, Henrique D. M. Coutinho   +4 more
wiley   +1 more source

The Anti-Inflammatory Effect of SDF-1 Derived Peptide on <i>Porphyromonas gingivalis</i> Infection via Regulation of NLRP3 and AIM2 Inflammasome. [PDF]

Pathogens
Kim SY, Son MK, Park JH, Na HS, Chung J.
europepmc   +1 more source

Atraumatic Versus Silver‐Modified Atraumatic Restorative Treatment in Primary Molars: A Randomized Clinical Trial on Minimally Invasive Caries Management and Oral Health‐Related Quality of Life

Clinical and Experimental Dental Research, Volume 12, Issue 1, February 2026.
ABSTRACT Objectives To compare the 6‐month clinical success of atraumatic restorative treatment (ART) and silver‐modified atraumatic restorative treatment (SMART) in primary molars of children with early childhood caries (ECC), and to assess the impact of these treatments on oral health‐related quality of life (OHRQoL).
Sana K. Solh, Ahmed A. Holiel, Ahmad S. Tarabaih   +2 more
wiley   +1 more source

Modeling the SDF-1/CXCR4 protein using advanced artificial intelligence and antagonist screening for Japanese anchovy. [PDF]

Front Physiol
Yahiro I, Barnuevo KDE, Sato O, Mohapatra S, Toyoda A, Itoh T, Ohno K, Matsuyama M, Chakraborty T, Ohta K.   +9 more
europepmc   +1 more source

Therapeutic Potential of Mesenchymal Stem Cells in Pediatric Kidney Disorders: A Comprehensive Review

Health Science Reports, Volume 9, Issue 2, February 2026.
ABSTRACT Background Kidney diseases in children present significant health challenges, often leading to complications and reduced quality of life. Mesenchymal stem cell (MSC) therapy shows promise for pediatric kidney disorders. This review evaluates current evidence on MSC applications in pediatric nephrology, focusing on mechanisms, delivery methods,
Mahboube Bahroudi, Mastaneh Moghtaderi
wiley   +1 more source