Results 91 to 100 of about 3,539,778 (300)
The last glaciation of Shetland : local ice cap or invasive ice sheet? [PDF]
, 2014 Issue ISBN: 978-82-92-39488-5 This work is supported by the Carnegie Trust for the Universities of ScotlandThe question of whether the Shetland Islands were covered by an ice cap or by an ice sheet during the last glacial cycle (40–10 ka) remains ...
Hall, A. M.
core +2 more sources
Assessing the O2 budget under sea ice: An experimental and modelling approach
Elementa: Science of the Anthropocene, 2015 The objective of this study was to assess the O2 budget in the water under sea ice combining observations and modelling. Modelling was used to discriminate between physical processes, gas-specific transport (i.e., ice-atmosphere gas fluxes and gas bubble
S. Moreau +8 more
doaj +1 more source
Modeling the morphogenesis of brine channels in sea ice [PDF]
Physical Review E, 2010 Brine channels are formed in sea ice under certain constraints and represent a habitat of different microorganisms. The complex system depends on a number of various quantities as salinity, density, pH-value or temperature. Each quantity governs the process of brine channel formation. There exists a strong link between bulk salinity and the presence of
Kutschan, B., Morawetz, K., Gemming, S.
openaire +5 more sources
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Using sea-level and land motion data to develop an improved glacial isostatic adjustment model for the British Isles [PDF]
, 2011 The Glacial Isostatic Adjustment (GIA) of the British Isles is of interest due to the constraints that can be provided on key model parameters such as regional ice sheet history, viscoelastic earth structure and the global meltwater (eustatic) signal ...
Bradley, Sarah Louise +1 more
core
Annals of Glaciology, 2020 We examine the relative effect of warming events (storms) and snow cover on thermodynamic growth of Arctic sea ice in winter. We use a 1-D snow and ice thermodynamic model to perform sensitivity experiments.
Ioanna Merkouriadi +3 more
doaj +1 more source
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
Geophysical Research Letters, 2000 Combining field measurements, remote sensing and numerical modelling, a key site for ice entrainment and basinwide dispersal of sediments by sea ice has been identified near the New Siberian Islands.
Hajo Eicken +5 more
doaj +1 more source
, 2023 Master thesis done at the Alfred-Wegener-Institute as submitted to the University of Bremen.
openaire +2 more sources
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source