Results 91 to 100 of about 554,659 (340)
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
What sea-ice biogeochemical modellers need from observers
Elementa: Science of the Anthropocene, 2016 Numerical models can be a powerful tool helping to understand the role biogeochemical processes play in local and global systems and how this role may be altered in a changing climate.
Nadja Steiner +9 more
doaj +1 more source
Optimising assimilation of sea ice concentration in an Earth system model with a multicategory sea ice model [PDF]
Tellus A: Dynamic Meteorology and Oceanography, 2018 A data assimilation method capable of constraining the sea ice of an Earth system model in a dynamically consistent manner has the potential to enhance the accuracy of climate reconstructions and predictions. Finding such a method is challenging because the sea ice dynamics is highly non-linear, and sea ice variables are strongly non-Gaussian ...
Kimmritz, M. +5 more
openaire +3 more sources
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
COAPEC: Newsletter No. 4 [PDF]
, 2004 The fourth of an irregular series of Newsletters with brief reports on meetings and projects associated with the NERC’s COAPEC directed programme. Article: Programme News Article: Bjerknes Compensation and the Decadal Variability of Energy Transports in
core
Arctic sea ice and Eurasian climate: A review
Advances in Atmospheric Sciences, 2014 The Arctic plays a fundamental role in the climate system and has shown significant climate change in recent decades, including the Arctic warming and decline of Arctic sea-ice extent and thickness.
Yongqi Gao +10 more
semanticscholar +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Present State and Prospects of Ice Sheet and Glacier Modelling [PDF]
, 2018 Since the late 1970s, numerical modelling has become established as an important technique for the understanding of ice sheet and glacier dynamics, and several models have been developed over the years.
Abe-Ouchi, Ayako +2 more
core
State-of-the-art in studies of glacial isostatic adjustment for the British Isles: a literature review [PDF]
, 2016 Understanding the effects of glacial isostatic adjustment (GIA) of the British Isles is essential for the assessment of past and future sea-level trends.
Alistair Rennie +36 more
core +1 more source