Results 81 to 90 of about 554,659 (340)

ICESHEET 1.0: a program to produce paleo-ice sheet reconstructions with minimal assumptions [PDF]

open access: yesGeoscientific Model Development, 2016
We describe a program that produces paleo-ice sheet reconstructions using an assumption of steady-state, perfectly plastic ice flow behaviour. It incorporates three input parameters: ice margin, basal shear stress and basal topography.
E. J. Gowan   +6 more
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

High-resolution regional sea-ice model based on the discrete element method with boundary conditions from a large-scale model for ice drift

open access: yesAnnals of Glaciology
Understanding sea-ice dynamics at the floe scale is crucial to comprehend polar climate systems. While continuum models are commonly used to simulate large-scale sea-ice dynamics, they have limitations in accurately representing sea-ice behaviour at ...
Andrei Tsarau   +4 more
doaj   +1 more source

Estimating Arctic Sea Ice Thickness with CryoSat-2 Altimetry Data Using the Least Squares Adjustment Method

open access: yesSensors, 2020
Satellite altimeters can be used to derive long-term and large-scale sea ice thickness changes. Sea ice thickness retrieval is based on measurements of freeboard, and the conversion of freeboard to thickness requires knowledge of the snow depth and snow,
Feng Xiao   +5 more
doaj   +1 more source

Comparing sea ice, hydrography and circulation between NEMO3.6 LIM3 and LIM2 [PDF]

open access: yesGeoscientific Model Development, 2017
A set of hindcast simulations with the new version 3.6 of the Nucleus for European Modelling of the Ocean (NEMO) ocean–ice model in the ORCA1 configuration and forced by the DRAKKAR Forcing Set version 5.2 (DFS5.2) atmospheric data was performed from ...
P. Uotila   +4 more
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Solitary flexural–gravity waves in three dimensions [PDF]

open access: yes, 2018
The focus of this work is on three-dimensional nonlinear flexural–gravity waves, propagating at the interface between a fluid and an ice sheet. The ice sheet is modelled using the special Cosserat theory of hyperelastic shells satisfying Kirchhoff's ...
Milewski, Paul   +3 more
core   +2 more sources

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

Instantaneous Antarctic ice-sheet mass loss driven by thinning ice shelves [PDF]

open access: yes, 2019
Recent observations show that the rate at which the Antarctic Ice Sheet (AIS) is contributing to sea level rise is increasing. Increasing ice-ocean heat exchange has the potential to induce substantial mass loss through the melting of its ice shelves ...
Adusumilli, Susheel   +3 more
core   +1 more source

The Louvain-La-Neuve sea ice model LIM3.6: global and regional capabilities

open access: yes, 2015
The new 3.6 version of the Louvain-la-Neuve sea ice model (LIM) is presented, as integrated in the most recent stable release of Nucleus for European Modelling of the Ocean (NEMO) (3.6).
C. Rousset   +10 more
semanticscholar   +1 more source

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