Results 101 to 110 of about 3,636 (228)

Acceptability by community health workers in Senegal of combining community case management of malaria and seasonal malaria chemoprevention [PDF]

Malaria Journal, 2013
Community case management of malaria (CCMm) and seasonal malaria chemoprevention (SMC) are anti-malarial interventions that can lead to substantial reduction in malaria burden acting in synergy. However, little is known about the social acceptability of these interventions.
Tine, Roger Ck, Ndiaye, Pascal, Ndour, Cheikh T, Faye, Babacar, Ndiaye, Jean L, Sylla, Khadime, Ndiaye, Magatte, Cisse, Badara, Sow, Doudou, Magnussen, Pascal, Bygbjerg, Ib C, Gaye, Oumar   +11 more
openaire   +4 more sources

Micronutrient Powders Combined With Malaria Chemoprevention to Improve Anaemia and Cognitive Function in Early Childhood in Mali: A Cluster‐Randomised Trial

Maternal &Child Nutrition, Volume 21, Issue 4, October 2025.
Globally nearly 40% of children under 5 years old are anaemic, which affects their ability to grow and develop. A cluster randomised trial was conducted in 60 communities in Southern Mali to evaluate the added impact of home fortification with micronutrient powders, delivered alongside seasonal malaria chemoprevention, on anaemia, malaria infection ...
Niélé H. Diarra, Yahia Dicko, Natalie Roschnik, Modibo Bamadio, Michael Boivin, Yvonne Griffiths, Rebecca Jones, Sham Lal, Helen Moestue, Hamidou Niangaly, Lauren Pisani, Renion Saye, Kalifa Sidibe, Karla Smuts, Nia‐An Philippe Thera, Josselin Thuilliez, Hans Verhoef, Moussa Sacko, Siân E. Clarke   +18 more
wiley   +1 more source

Effectiveness of seasonal malaria chemoprevention in reducing under-five malaria morbidity and mortality in the Savannah Region, Ghana

Ghana Medical Journal, 2022
Objective: To assess the effectiveness of seasonal malaria chemoprevention (SMC) in reducing under-five malaria morbidity and mortalityDesign: Under-five malaria data for confirmed episodes, deaths, and number of children dosed per cycle of SMC campaign were extracted from the District Health Information Management System (DHIMS-2) for 2018-2019.
R Adjei, Michael, Kubio, Chrysantus, Buamah, Marcel, Sarfo, Adjei, Suuri, Thomas, Ibrahim, Saeed, Sadiq, Abubakari, I Abubakari, Ihsan, V Baafi, Janet   +8 more
openaire   +3 more sources

Opportunities and Challenges of Population Pharmacogenomics

Annals of Human Genetics, Volume 89, Issue 5, Page 384-397, September 2025.
ABSTRACT Pharmacological responses can vary significantly among patients from different ethnogeographic backgrounds. This variability can, at least in part, be attributed to population‐specific genetic patterns in genes involved in drug absorption, distribution, metabolism, and excretion, as well as in genes associated with drug‐induced toxicity ...
Yitian Zhou, Yoomi Park, Mahamadou D. Camara, Volker M. Lauschke   +3 more
wiley   +1 more source

Gametocyte carriage after seasonal malaria chemoprevention in Plasmodium falciparum infected asymptomatic children [PDF]

Malaria Journal, 2020
Abstract Background Treatment of clinical Plasmodium falciparum malaria with sulfadoxine-pyrimethamine (SP) and amodiaquine (AQ) is associated with increased post-treatment gametocyte carriage. The effect of seasonal malaria chemoprevention (SMC) with SP and AQ on gametocyte carriage was assessed in asymptomatic P ...
Abdullahi Ahmad, Abdullahi Ahmad, Mamadou Ousmane Ndiath, John S. Bradley, Jean-Pierre Van Geertruyden, Teun Bousema, Jane Achan, Mamadou Bah, Aurelia Prom, Umberto D'Alessandro, Blessed Etoketim, Chris Drakeley   +11 more
openaire   +8 more sources

Use of population pharmacokinetic‐pharmacodynamic modelling to inform antimalarial dose optimization in infants

British Journal of Clinical Pharmacology, Volume 91, Issue 4, Page 968-980, April 2025.
Infants bear a significant malaria burden but are usually excluded from participating in early dose optimization studies that inform dosing regimens of antimalarial therapy. Unlike older children, infants' exclusion from early‐phase trials has resulted in limited evidence to guide accurate dosing of antimalarial treatment for uncomplicated malaria or ...
Clifford G. Banda, Joel Tarning, Karen I. Barnes   +2 more
wiley   +1 more source

Pharmacokinetics of a Novel Piperaquine Dispersible Granules Formulation Under Fasting and Various Fed Conditions Versus Piperaquine Tablets When Fasted in Healthy Tanzanian Adults: A Randomized, Phase I Study

Clinical and Translational Science, Volume 18, Issue 2, February 2025.
ABSTRACT Piperaquine tetraphosphate (PQP), a long‐acting antimalarial, is being considered in a combination for chemoprevention. Dihydroartemisinin‐piperaquine tablets (hard and dispersible) approved for the treatment of acute uncomplicated malaria should be administered in a fasted state, as PQP bioavailability increases with food.
Florence A. Milando, Said Jongo, Salim Abdulla, Gloria Nyaulingo, Anneth‐Mwasi Tumbo, Sarah Mswata, Juliether Tiago, Beatus S. Bongole, Ashura Mirambo, Kamaka Kassimu, Hussein Mbarak, Mohammed A. Rashid, Ali Hamad, Michael Mihayo, Tunu Ndanzi, Omary Zuberi, Naima Saadia, Mariam Somboka, Mariam Yamba‐Yamba, Theresia Ngonyani, Amina Nditi, Margaret Msuya, Bakari Mwalimu, Hajirani M. Msuya, Khamis Awadh, Ali Ali, Anne Claire Marrast, Denis Gossen, Alice Neequaye, Myriam El‐Gaaloul, Hanu Ramachandruni, Isabelle Borghini‐Fuhrer   +31 more
wiley   +1 more source

Malaria intervention scale-up in Africa : effectiveness predictions for health programme planning tools, based on dynamic transmission modelling [PDF]

, 2016
Scale-up of malaria prevention and treatment needs to continue to further important gains made in the past decade, but national strategies and budget allocations are not always evidence-based.
Briët, Olivier J. T., Cibulskis, Richard, Hamilton, Matthew, Korenromp, Eline, Lauer, Jeremy, Mahiané, Guy, Pretorius, Carel, Smith, Thomas A.   +7 more
core   +6 more sources

Population impact of malaria control interventions in the health district of Kati, Mali.

PLoS ONE
BackgroundWHO and its partners have adopted alternative control interventions since the failure to eradicate malaria worldwide in the 1960s and 1970s.
Abdoulaye Katile, Issaka Sagara, Mady Cissoko, Cédric Stéphane Bationo, Mathias Dolo, Pascal Dembélé, Bourama Kamate, Ismaila Simaga, Mahamadou Soumana Sissoko, Jordi Landier, Jean Gaudart   +10 more
doaj   +1 more source

Evaluation of the implementation fidelity of the seasonal malaria chemoprevention intervention in Kaya health district, Burkina Faso. [PDF]

PLoS ONE, 2017
Burkina Faso implemented the seasonal malaria chemoprevention (SMC) in 2014 in seven pilot health districts, following the new recommendation by the WHO in 2012 for the prevention of the disease in children under five years old, for areas of highly ...
Rachidatou Compaoré, Maurice Wambi Evariste Yameogo, Tieba Millogo, Halima Tougri, Seni Kouanda   +4 more
doaj   +1 more source