Results 101 to 110 of about 8,311 (256)

Review of contextual factors related to seasonal malaria chemoprevention

, 2022
Report considered by the WHO/GMP Guideline Development Group on Malaria Chemoprevention for “Section 4.2.3 Seasonal malaria chemoprevention (SMC)” of the WHO Guidelines for malaria, 3 June 2022.
Bhattarai A, Thwing J, Williamson J, Cavros I, Gutman J   +4 more
openaire   +1 more source

Impact of a malaria intervention package in schools on Plasmodium infection, anaemia and cognitive function in schoolchildren in Mali: a pragmatic cluster-randomised trial. [PDF]

, 2017
BACKGROUND: School-aged children are rarely targeted by malaria control programmes, yet the prevalence of Plasmodium infection in primary school children often exceeds that seen in younger children and could affect haemoglobin concentration and school ...
Bamadio, Modibo, Brooker, Simon, Clarke, Siân E, Diarra, Seybou, Jones, Rebecca, Jukes, Matthew Ch, Roschnik, Natalie, Rouhani, Saba, Sacko, Moussa, Saye, Renion, Thuilliez, Josselin, Traore, Diahara, Traore, Klenon   +12 more
core   +4 more sources

Epidemiology of malaria in an area of seasonal transmission in Niger and implications for the design of a seasonal malaria chemoprevention strategy [PDF]

Malaria Journal, 2013
Abstract Background Few data are available about malaria epidemiological situation in Niger. However, implementation of new strategies such as vaccination or seasonal treatment of a target population requires the knowledge of baseline epidemiological features of malaria.
Julia Guillebaud, Aboubacar Mahamadou, Halima Zamanka, Mariama Katzelma, Ibrahim Arzika, Maman Laminou Ibrahim, Elfatih A. B. Eltahir, Rabiou Labbo, Pierre Druilhe, Jean‐Bernard Duchemin, Thierry Fandeur   +10 more
openalex   +7 more sources

Opportunities and Challenges of Population Pharmacogenomics

Annals of Human Genetics, Volume 89, Issue 5, Page 384-397, September 2025.
ABSTRACT Pharmacological responses can vary significantly among patients from different ethnogeographic backgrounds. This variability can, at least in part, be attributed to population‐specific genetic patterns in genes involved in drug absorption, distribution, metabolism, and excretion, as well as in genes associated with drug‐induced toxicity ...
Yitian Zhou, Yoomi Park, Mahamadou D. Camara, Volker M. Lauschke   +3 more
wiley   +1 more source

Tools and Strategies for Malaria Control and Elimination: What Do We Need to Achieve a Grand Convergence in Malaria? [PDF]

, 2016
Progress made in malaria control during the past decade has prompted increasing global dialogue on malaria elimination and eradication. The product development pipeline for malaria has never been stronger, with promising new tools to detect, treat, and ...
Achee, Nicole, Bell, David, Djimdé, Abdoulaye A., Hemingway, Janet, Qi, Gao, Shretta, Rima, Wells, Timothy N. C.   +6 more
core   +3 more sources

Use of population pharmacokinetic‐pharmacodynamic modelling to inform antimalarial dose optimization in infants

British Journal of Clinical Pharmacology, Volume 91, Issue 4, Page 968-980, April 2025.
Infants bear a significant malaria burden but are usually excluded from participating in early dose optimization studies that inform dosing regimens of antimalarial therapy. Unlike older children, infants' exclusion from early‐phase trials has resulted in limited evidence to guide accurate dosing of antimalarial treatment for uncomplicated malaria or ...
Clifford G. Banda, Joel Tarning, Karen I. Barnes   +2 more
wiley   +1 more source

Effect of seasonal malaria chemoprevention on the acquisition of antibodies to Plasmodium falciparum antigens in Ouelessebougou, Mali

Malaria Journal, 2017
Background Seasonal malaria chemoprevention (SMC) is a new strategy to reduce malaria burden in young children in Sahelian countries. It consists of the administration of full treatment courses of sulfadoxine–pyrimethamine plus amodiaquine to children at
Almahamoudou Mahamar, Djibrilla Issiaka, Amadou Barry, Oumar Attaher, Adama B. Dembele, Tiangoua Traore, Adama Sissoko, Sekouba Keita, Bacary Soumana Diarra, David L. Narum, Patrick E. Duffy, Alassane Dicko, Michal Fried   +12 more
doaj   +1 more source

Effectiveness of seasonal malaria chemoprevention in three regions of Togo: a population-based longitudinal study from 2013 to 2020

Malaria Journal, 2022
Background In 2012, the World Health Organization (WHO) recommended seasonal malaria chemoprevention (SMC) in areas of high seasonal transmission. Though implemented since 2013, the effectiveness of SMC in Togo was never evaluated.
Tchaa A. Bakai, Anne Thomas, Jean Iwaz, Tinah Atcha-Oubou, Tchassama Tchadjobo, Nagham Khanafer, Muriel Rabilloud, Nicolas Voirin   +7 more
doaj   +1 more source

Mathematical Analysis of a Seasonal Malaria Chemoprevention (SMC) Intervention in Children Under 5 Years: Application to Senegal

Journal of Information Systems Engineering & Management
Malaria remains a major cause of morbidity and mortality among children under 5 years old in Senegal. To alleviate this burden, Seasonal Malaria Chemoprevention (SMC) administers antimalarial drugs during the high transmission season.
Moussa Kane, Karim Konate, O. Sy, O. Gaye   +3 more
semanticscholar   +1 more source

Pharmacokinetics of a Novel Piperaquine Dispersible Granules Formulation Under Fasting and Various Fed Conditions Versus Piperaquine Tablets When Fasted in Healthy Tanzanian Adults: A Randomized, Phase I Study

Clinical and Translational Science, Volume 18, Issue 2, February 2025.
ABSTRACT Piperaquine tetraphosphate (PQP), a long‐acting antimalarial, is being considered in a combination for chemoprevention. Dihydroartemisinin‐piperaquine tablets (hard and dispersible) approved for the treatment of acute uncomplicated malaria should be administered in a fasted state, as PQP bioavailability increases with food.
Florence A. Milando, Said Jongo, Salim Abdulla, Gloria Nyaulingo, Anneth‐Mwasi Tumbo, Sarah Mswata, Juliether Tiago, Beatus S. Bongole, Ashura Mirambo, Kamaka Kassimu, Hussein Mbarak, Mohammed A. Rashid, Ali Hamad, Michael Mihayo, Tunu Ndanzi, Omary Zuberi, Naima Saadia, Mariam Somboka, Mariam Yamba‐Yamba, Theresia Ngonyani, Amina Nditi, Margaret Msuya, Bakari Mwalimu, Hajirani M. Msuya, Khamis Awadh, Ali Ali, Anne Claire Marrast, Denis Gossen, Alice Neequaye, Myriam El‐Gaaloul, Hanu Ramachandruni, Isabelle Borghini‐Fuhrer   +31 more
wiley   +1 more source