Dihydroartemisinin-piperaquine effectiveness for seasonal malaria chemoprevention in settings with extended seasonal malaria transmission in Tanzania [PDF]
Scientific ReportsEffectiveness of dihydroartemisinin-piperaquine (DP) as seasonal malaria chemoprevention (SMC) was assessed in Nanyumbu and Masasi Districts. Between March and June 2021, children aged 3–59 months were enrolled in a cluster randomized study.
Richard Mwaiswelo +7 more
doaj +4 more sources
Household-level effects of seasonal malaria chemoprevention in the Gambia. [PDF]
Commun Med (Lond), 2023 Abstract Background In 2022 the WHO recommended the discretionary expansion of the eligible age range for seasonal malaria chemoprevention (SMC) to children older than 4 years. Older children are at lower risk of clinical disease and severe malaria so there has been uncertainty about the cost-benefit for national control
Soremekun S +11 more
europepmc +9 more sources
Seasonal Malaria Chemoprevention: An Evolving Research Paradigm. [PDF]
PLoS Medicine, 2016 Robert W. Snow discusses the importance of empirical evidence, such as that provided in the trial published this week by Milligan and colleagues, in guiding malaria control in Africa.
Robert W Snow
doaj +4 more sources
Abstract Vaccines, monoclonal antibodies, and long-acting injectables are being developed to prevent Plasmodium falciparum malaria. These therapeutics may target multiple stages of the parasite life cycle; evidence is needed to articulate their benefits with chemoprevention and prioritise candidates for clinical development.
Braunack-Mayer L +5 more
europepmc +3 more sources
Seasonal malaria chemoprevention: successes and missed opportunities [PDF]
Malaria Journal, 2017 Seasonal malaria chemoprevention (SMC) was recommended in 2012 for young children in the Sahel during the peak malaria transmission season. Children are given a single dose of sulfadoxine/pyrimethamine combined with a 3-day course of amodiaquine, once a ...
Matthew E. Coldiron +2 more
doaj +3 more sources
Facilitators and Barriers to Uptake of an Extended Seasonal Malaria Chemoprevention Programme in Ghana: A Qualitative Study of Caregivers and Community Health Workers. [PDF]
PLoS ONE, 2016 BackgroundSeasonal Malaria Chemoprevention (SMC) is currently recommended for children under five in areas where malaria transmission is highly seasonal.
Gifty D Antwi +6 more
doaj +6 more sources
Impact of seasonal malaria chemoprevention based on the number of medicines doses received on malaria burden among children aged 3–59 months in Nigeria: A propensity score‐matched analysis [PDF]
Tropical Medicine &International Health, Volume 29, Issue 8, Page 668-679, August 2024.Abstract Background Seasonal malaria chemoprevention using sulfadoxine‐pyrimethamine plus amodiaquine (sulfadoxine‐pyrimethamine plus amodiaquine on Day 1 and amodiaquine on both Day 2 and Day 3) is delivered to children aged 3–59 months in areas of highly season malaria transmission.
Sikai Huang +5 more
wiley +2 more sources
Evaluating the effectiveness and cost-effectiveness of integrating mass drug administration for helminth control with seasonal malaria chemoprevention in Ghanaian children: Protocol for a cluster randomised controlled trial. [PDF]
Trop Med Int HealthAbstract Objectives To evaluate the effectiveness and cost‐effectiveness of integrating seasonal malaria chemoprevention (SMC) with mass drug administration for helminth control among school‐aged children living in communities where the burden of malaria and helminths is high in Ghana, West Africa.
Afolabi MO +6 more
europepmc +2 more sources
Seasonal malaria chemoprevention in an area of extended seasonal transmission in Ashanti, Ghana: an individually randomised clinical trial. [PDF]
Tropical Medicine & International Health, 2015 OBJECTIVE: To investigate the effectiveness of seasonal malaria chemoprevention (SMC) and community case management with long-acting artemisinin-based combination therapies (ACTs) for the control of malaria in areas of extended seasonal malaria ...
Acheampong, Princess Ruhama +5 more
core +5 more sources
Impact of seasonal malaria chemoprevention: a plausibility evaluation of routine data from health facilities in three implementing states in Nigeria. [PDF]
Malar JIkechukwu EC +13 more
europepmc +3 more sources