Results 11 to 20 of about 3,965 (238)

Seasonal Malaria Vaccination with or without Seasonal Malaria Chemoprevention [PDF]

New England Journal of Medicine, 2021
Malaria control remains a challenge in many parts of the Sahel and sub-Sahel regions of Africa.We conducted an individually randomized, controlled trial to assess whether seasonal vaccination with RTS,S/AS01E was noninferior to chemoprevention in preventing uncomplicated malaria and whether the two interventions combined were superior to either one ...
Chandramohan, Daniel, Zongo, Issaka, Sagara, Issaka, Cairns, Matthew, Yerbanga, Rakiswendé-Serge, Diarra, Modibo, Nikièma, Frédéric, Tapily, Amadou, Sompougdou, Frédéric, Issiaka, Djibrilla, Zoungrana, Charles, Sanogo, Koualy, Haro, Alassane, Kaya, Mahamadou, Sienou, Abdoul-Aziz, Traore, Seydou, Mahamar, Almahamoudou, Thera, Ismaila, Diarra, Kalifa, Dolo, Amagana, Kuepfer, Irene, Snell, Paul, Milligan, Paul, Ockenhouse, Christian, Ofori-Anyinam, Opokua, Tinto, Halidou, Djimde, Abdoulaye, Ouédraogo, Jean-Bosco, Dicko, Alassane, Greenwood, Brian   +29 more
openaire   +4 more sources

Seasonal Malaria Chemoprevention Implementation: Effect on Malaria Incidence and Immunity in a Context of Expansion of P. falciparum Resistant Genotypes with Potential Reduction of the Effectiveness in Sub-Saharan Africa

Infection and Drug Resistance, 2022
Séni Nikiema,1,2 Issiaka Soulama,1,3 Salif Sombié,1 André-Marie Tchouatieu,4 Samuel Sindie Sermé,5 Noëlie Béré Henry,5 Nicolas Ouedraogo,1 Nathalie Ouaré,1,6 Raissa Ily,1,6 Oumarou Ouédraogo,3 Dramane Zongo,3 Florencia Wendkuuni Djigma,2 Alfred B Tiono,1
Nikiema S, Soulama I, Sombié S, Tchouatieu AM, Sermé SS, Henry NB, Ouedraogo N, Ouaré N, Ily R, Ouédraogo O, Zongo D, Djigma FW, Tiono AB, Sirima SB, Simporé J   +14 more
doaj   +3 more sources

Assessing the Acceptability and Feasibility of Five Cycles of Seasonal Malaria Chemoprevention in Côte d’Ivoire [PDF]

Tropical Medicine and Infectious Disease
Seasonal malaria chemoprevention (SMC) is a strategy recommended by the World Health Organization for children aged 3–59 months in the Sahel and sub-Sahel regions where malaria transmission is seasonal.
Orphée Kangah, Issaka Zongo, Alassane Haro, William Yavo   +3 more
doaj   +2 more sources

Seasonal Malaria Chemoprevention: An Evolving Research Paradigm.

PLoS Medicine, 2016
Robert W. Snow discusses the importance of empirical evidence, such as that provided in the trial published this week by Milligan and colleagues, in guiding malaria control in Africa.
Robert W Snow
doaj   +4 more sources

Trends in uncomplicated and severe malaria following seasonal malaria chemoprevention administration in Nouna, Burkina Faso: a quasi-experimental pre-post study [PDF]

Malaria Journal
Background While Seasonal Malaria Chemoprevention (SMC) has been adopted as a malaria control strategy in regions with seasonal transmission, continued monitoring and evaluation of its effectiveness across diverse ecological, epidemiological, and ...
Elisabeth A. Gebreegziabher, Mamadou Ouattara, Mamadou Bountogo, Boubacar Coulibaly, Valentin Boudo, Thierry Ouedraogo, Elodie Lebas, Huiyu Hu, David V. Glidden, Benjamin F. Arnold, Thomas M. Lietman, Ali Sié, Catherine E. Oldenburg   +12 more
doaj   +2 more sources

Malaria parasite carriage before and two years after the implementation of seasonal malaria chemoprevention: a case study of the Saraya health district, southern Senegal [version 2; peer review: 2 approved]

Wellcome Open Research, 2022
Background: Seasonal malaria chemoprevention (SMC) has been adopted and implemented in the southern regions of Senegal in children aged between three and 120 months since 2013. Scaling up this strategy requires its evaluation to assess the impact.
Isaac Akhenaton Manga, Fassiatou Tairou, Mamadou Sarifou BA, Ekoue Kouevidjin, Amadou Seck, Magatte Ndiaye, Doudou Sow, Médoune Ndiop, Khadime Sylla, Alioune Babara Gueye, Mady Ba, Fatou Ba Fall, Ibrahima Diallo, Omar Gaye, Roger Clément Tine, Jean Louis Abdourahim Ndiaye, Babacar Faye   +16 more
doaj   +2 more sources

Assessing the effect of seasonal malaria chemoprevention on malaria burden among children under 5 years in Burkina Faso [PDF]

Malaria Journal, 2022
Background In 2014, the Burkina Faso government launched the Seasonal Malaria Chemoprevention (SMC) programme. Expected benefit was a 75% reduction of all malaria episodes and a 75% drop of severe malaria episodes.
Fati Kirakoya-Samadoulougou, Vincent De Brouwere, Arnold Fottsoh Fokam, Mady Ouédraogo, Yazoumé Yé   +4 more
doaj   +2 more sources

Parasitological efficacy of seasonal malaria chemoprevention in Nampula, northern Mozambique. [PDF]

Trans R Soc Trop Med Hyg
Abstract Background Deployment of seasonal malaria chemoprevention (SMC) for young children using monthly sulphadoxine-pyrimethamine-amodiaquine (SPAQ) has recently been extended to Central and East Africa.
Bonnington C, Sitoe M, Pulido Tarquino IA, Enosse SM, Sararat C, Suwannasin K, Proux S, Koesukwiwat U, Tarning J, Imwong M, Theiss-Nyland K, Nosten FH, White NJ.   +12 more
europepmc   +2 more sources

Facilitators and Barriers to Uptake of an Extended Seasonal Malaria Chemoprevention Programme in Ghana: A Qualitative Study of Caregivers and Community Health Workers. [PDF]

PLoS ONE, 2016
BackgroundSeasonal Malaria Chemoprevention (SMC) is currently recommended for children under five in areas where malaria transmission is highly seasonal.
Gifty D Antwi, Laura A Bates, Rebecca King, Princess R Mahama, Harry Tagbor, Matt Cairns, James N Newell   +6 more
doaj   +5 more sources

Evaluation of direct and indirect effects of seasonal malaria chemoprevention in Mali [PDF]

Scientific Reports, 2018
AbstractRandomized controlled trials have established that seasonal malaria chemoprevention (SMC) in children is a promising strategy to reduce malaria transmission in Sahelian West Africa. This strategy was recently introduced in a dozen countries, and about 12 million children received SMC in 2016. However, evidence on SMC effectiveness under routine
Thomas Druetz
openalex   +4 more sources