Results 11 to 20 of about 1,896 (179)

Evaluation of seasonal malaria chemoprevention implementation in the Upper East region of Northern Ghana. [PDF]

Malar J
Ghana adopted the WHO-recommended Seasonal Malaria Chemoprevention (SMC) in 2016 following a pilot study as a vital strategy for malaria control. SMC is the intermittent administration of a preventive and curative dose of anti-malarial medicine (Sulfadoxine-Pyrimetamine + Amodiaquine) during four months of the malaria season.
Ayamba EY, Dzotsi EK, Dormechele W, Ansah NA, Bangre O, Nyuzaghl JA, Abilba SA, Boakye-Boateng SK, Ansah PO.   +8 more
europepmc   +5 more sources

Seasonal Malaria Vaccination with or without Seasonal Malaria Chemoprevention [PDF]

New England Journal of Medicine, 2021
Malaria control remains a challenge in many parts of the Sahel and sub-Sahel regions of Africa.We conducted an individually randomized, controlled trial to assess whether seasonal vaccination with RTS,S/AS01E was noninferior to chemoprevention in preventing uncomplicated malaria and whether the two interventions combined were superior to either one ...
Daniel Chandramohan, Issaka Zongo, Issaka Sagara, Matthew Cairns, Rakiswendé-Serge Yerbanga, Modibo Diarra, Frédéric Nikièma, Amadou Tapily, Frédéric Sompougdou, Djibrilla Issiaka, Charles Zoungrana, Koualy Sanogo, Alassane Haro, Mahamadou Kaya, Abdoul-Aziz Sienou, Seydou Traoré, Almahamoudou Mahamar, Ismaïla Thera, Kalifa Diarra, Amagana Dolo, Irene Kuepfer, Paul Snell, Paul Milligan, Christian F. Ockenhouse, Opokua Ofori‐Anyinam, Halidou Tinto, Abdoulaye Djimdé, Jean‐Bosco Ouédraogo, Alassane Dicko, Brian Greenwood   +29 more
openalex   +5 more sources

Evaluating the effectiveness and cost-effectiveness of integrating mass drug administration for helminth control with seasonal malaria chemoprevention in Ghanaian children: Protocol for a cluster randomised controlled trial. [PDF]

Trop Med Int Health
Abstract Objectives To evaluate the effectiveness and cost‐effectiveness of integrating seasonal malaria chemoprevention (SMC) with mass drug administration for helminth control among school‐aged children living in communities where the burden of malaria and helminths is high in Ghana, West Africa.
Afolabi MO, Adu-Gyasi D, Paintain L, Tawiah T, Ali MS, Greenwood B, Asante KP.   +6 more
europepmc   +3 more sources

Predictors of caregiver adherence to administration of amodiaquine during delivery of seasonal malaria chemoprevention in Nigeria, Burkina Faso, Chad, and Togo [PDF]

Malaria Journal, 2023
Background Malaria is the leading cause of morbidity and mortality among infants and children under-five in sub-Saharan Africa. In the Sahel, seasonal malaria chemoprevention (SMC) is delivered door-to-door in monthly cycles.
Taiwo Ibinaiye, Olusola Oresanya, Chibuzo Oguoma, Adaeze Aidenagbon, Olabisi Ogunmola, Christian Rassi, Sol Richardson   +6 more
doaj   +2 more sources

Evidence that seasonal malaria chemoprevention with SPAQ influences blood and pre-erythrocytic stage antibody responses of Plasmodium falciparum infections in Niger [PDF]

Malaria Journal, 2021
Background In endemic areas, children develop slowly and naturally anti-Plasmodium antibodies and become semi-immune. Seasonal Malaria Chemoprevention (SMC) with sulfadoxine-pyrimethamine + amodiaquine (SPAQ) is a new strategy to reduce malaria morbidity
Lamine Mahaman Moustapha, Rafiou Adamou, Maman Laminou Ibrahim, Mariama Abdoulaye Louis Padounou, Abdoulaye Diallo, David Courtin, Jean Testa, Jean Louis Abdourahim Ndiaye   +7 more
doaj   +2 more sources

Cost-effectiveness of seasonal malaria chemoprevention in upper west region of Ghana [PDF]

Malaria Journal, 2016
In Ghana, malaria is endemic and perennial (with significant seasonal variations in the three Northern Regions), accounting for 33 % of all deaths among children under 5 years old, with prevalence rates in children under-five ranging from 11 % in Greater Accra to 40 % in Northern Region.
Justice Nonvignon, Genevieve Cecilia Aryeetey, Shamwill Issah, Patrick Ansah, Keziah Malm, Winfred Ofosu, Titus Tagoe, Samuel Agyei Agyemang, Moses Aikins   +8 more
openalex   +4 more sources

Systematic review on the cost of seasonal malaria chemoprevention (SMC). [PDF]

Malar J
Implemented in 17 countries to date, seasonal malaria chemoprevention (SMC) is a recommended strategy to prevent childhood malaria in areas with seasonal transmission of P. falciparum through monthly administration of antimalarial medicines. Understanding the costs and resource requirements of SMC delivery is necessary for effective planning and ...
Ruisch A, Iodice M, Mathur I, Harris S, Walker DG, Owusu R, Nonvignon J, Gilmartin C.   +7 more
europepmc   +4 more sources

Seasonal Malaria Chemoprevention: An Evolving Research Paradigm. [PDF]

PLoS Medicine, 2016
Robert W. Snow discusses the importance of empirical evidence, such as that provided in the trial published this week by Milligan and colleagues, in guiding malaria control in Africa.
Robert W Snow
doaj   +4 more sources

Measuring the impact of seasonal malaria chemoprevention as part of routine malaria control in Kita, Mali

Malaria Journal, 2017
Seasonal malaria chemoprevention (SMC) is a new strategy recommended by WHO in areas of highly seasonal transmission in March 2012. Although randomized controlled trials (RCTs) have shown SMC to be highly effective, evidence and experience from routine implementation of SMC are limited.A non-randomized pragmatic trial with pre-post design was used ...
Fatou Diawara, Laura C. Steinhardt, Almahamoudou Mahamar, Tiangoua Traore, Koné Daouda, Halimatou Diawara, Beh Kamaté, Diakalia Koné, Mouctar Diallo, Aboubacar Sadou, Jules Mihigo, Issaka Sagara, Abdoulaye Djimdé, Erin Eckert, Alassane Dicko   +14 more
openalex   +6 more sources

Seasonal malaria chemoprevention in Africa and China's upgraded role as a contributor: a scoping review. [PDF]

Infect Dis Poverty, 2023
Abstract Background Children under five are the vulnerable population most at risk of being infected with Plasmodium parasites, especially in the Sahel region. Seasonal malaria chemoprevention (SMC) recommended by World Health Organization (WHO), has proven to be a highly effective intervention to prevent malaria.
Xu M, Hu YX, Lu SN, Idris MA, Zhou SD, Yang J, Feng XN, Huang YM, Xu X, Chen Y, Wang DQ.   +10 more
europepmc   +4 more sources