Understanding and maximising the community impact of seasonal malaria chemoprevention in Burkina Faso (INDIE-SMC): study protocol for a cluster randomised evaluation trial. [PDF]
Introduction Seasonal malaria chemoprevention (SMC) involves repeated administrations of sulfadoxine-pyrimethamine plus amodiaquine to children below the age of 5 years during the peak transmission season in areas of seasonal malaria transmission.
Moreno M +22 more
europepmc +4 more sources
A cost analysis comparing seasonal malaria chemoprevention with and without Vitamin A supplementation among under-5 children in Nigeria. [PDF]
Oresanya OB +8 more
europepmc +3 more sources
Evidence that seasonal malaria chemoprevention with SPAQ influences blood and pre-erythrocytic stage antibody responses of Plasmodium falciparum infections in Niger [PDF]
Background In endemic areas, children develop slowly and naturally anti-Plasmodium antibodies and become semi-immune. Seasonal Malaria Chemoprevention (SMC) with sulfadoxine-pyrimethamine + amodiaquine (SPAQ) is a new strategy to reduce malaria morbidity
Lamine Mahaman Moustapha +7 more
doaj +2 more sources
Seasonal malaria chemoprevention: drug design and selection
Issaka Zongo, Yves Daniel Compaoré
semanticscholar +4 more sources
Evaluation of seasonal malaria chemoprevention implementation in the Upper East region of Northern Ghana. [PDF]
Ghana adopted the WHO-recommended Seasonal Malaria Chemoprevention (SMC) in 2016 following a pilot study as a vital strategy for malaria control. SMC is the intermittent administration of a preventive and curative dose of anti-malarial medicine (Sulfadoxine-Pyrimetamine + Amodiaquine) during four months of the malaria season.
Ayamba EY +8 more
europepmc +5 more sources
Seasonal Malaria Chemoprevention: An Evolving Research Paradigm. [PDF]
Robert W. Snow discusses the importance of empirical evidence, such as that provided in the trial published this week by Milligan and colleagues, in guiding malaria control in Africa.
Robert W Snow
doaj +4 more sources
Barriers to the quality delivery of seasonal malaria chemoprevention in Chad and Burkina Faso: a qualitative exploration of caregivers and community distributors' perspectives. [PDF]
Background Recommended since 2012 by the World Health Organization (WHO), seasonal malaria chemoprevention (SMC) is a community-based intervention to prevent malaria in children in African regions where malaria transmission follows a seasonal pattern ...
Lasmi K +11 more
europepmc +2 more sources
Adaptation of lot quality assurance sampling to monitor seasonal malaria chemoprevention delivery performance. [PDF]
Malaria Consortium supports delivery of seasonal malaria chemoprevention (SMC) to children ages 3–59 months using sulfadoxine–pyrimethamine plus amodiaquine.
Richardson S +11 more
europepmc +2 more sources
Seasonal malaria chemoprevention using sulfadoxine‐pyrimethamine plus amodiaquine (sulfadoxine‐pyrimethamine plus amodiaquine on Day 1 and amodiaquine on both Day 2 and Day 3) is delivered to children aged 3–59 months in areas of highly season malaria ...
Sikai Huang +5 more
semanticscholar +2 more sources
Malaria trends in districts that were targeted and not-targeted for seasonal malaria chemoprevention in children under 5 years of age in Guinea, 2014-2021. [PDF]
Background Seasonal malaria chemoprevention (SMC) is a main intervention to prevent and reduce childhood malaria. Since 2015, Guinea has implemented SMC targeting children aged 3–59 months (CU5) in districts with high and seasonal malaria transmission ...
Bisanzio D +12 more
europepmc +2 more sources

