Usefulness of seasonal malaria chemoprevention in the Sahel
Seasonal malaria chemoprevention is an important intervention recommended for children aged 3–59 months living in highly seasonal transmission areas of the Sahel subregion of Africa to provide protection against malaria during the rainy season. In The Lancet Infectious Diseases, Colin J Sutherland and colleagues report on the prevalence of Plasmodium ...
Kayiba Kalenda, Nadine +6 more
openaire +3 more sources
Background Seasonal administration of antimalaria drug, sulphadoxine/pyrimethamine plus amodiaquine to children 3–59 months is a malaria preventive intervention used for the reduction of childhood malaria morbidity and mortality in area with highly ...
Kunle Rotimi +11 more
doaj +1 more source
Malaria chemoprevention and drug resistance: a review of the literature and policy implications
Chemoprevention strategies reduce malaria disease and death, but the efficacy of anti-malarial drugs used for chemoprevention is perennially threatened by drug resistance.
Christopher V. Plowe
doaj +1 more source
Measuring the impact of seasonal malaria chemoprevention as part of routine malaria control in Kita, Mali [PDF]
Seasonal malaria chemoprevention (SMC) is a new strategy recommended by WHO in areas of highly seasonal transmission in March 2012. Although randomized controlled trials (RCTs) have shown SMC to be highly effective, evidence and experience from routine implementation of SMC are limited.A non-randomized pragmatic trial with pre-post design was used ...
Fatou Diawara +14 more
openalex +5 more sources
Background The World Health Organization (WHO) recommends seasonal malaria chemoprevention (SMC) with sulfadoxine-pyrimethamine and amodiaquine (SPAQ) for children aged 3 to 59 months, living in areas where malaria transmission is highly seasonal ...
Craig Bonnington +12 more
doaj +1 more source
Shifts in the clinical epidemiology of severe malaria after scaling up control strategies in Mali
A decrease in malaria incidence following implementation of control strategies such as use of artemisinin-based combination therapies, insecticide-impregnated nets, intermittent preventive treatment during pregnancy and seasonal malaria chemoprevention ...
Drissa Coulibaly +14 more
doaj +1 more source
Effect of Adding Azithromycin to Seasonal Malaria Chemoprevention [PDF]
Mass administration of azithromycin for trachoma control led to a sustained reduction in all-cause mortality among Ethiopian children. Whether the addition of azithromycin to the monthly sulfadoxine-pyrimethamine plus amodiaquine used for seasonal malaria chemoprevention could reduce mortality and morbidity among African children was unclear.We ...
Chandramohan, Daniel +18 more
openaire +2 more sources
Impact of seasonal malaria chemoprevention on prevalence of malaria infection in malaria indicator surveys in Burkina Faso and Nigeria [PDF]
Background In 2012, the WHO issued a policy recommendation for the use of seasonal malaria chemoprevention (SMC) to children 3–59 months in areas of highly seasonal malaria transmission. Clinical trials have found SMC to prevent around 75% of clinical malaria.
Monica Anna de Cola +12 more
openaire +5 more sources
Seasonal malaria chemoprevention and mutations in <i>Pfdhfr</i> and <i>Pfdhps</i> genes in children in the health district of Nanoro, Burkina Faso. [PDF]
Millogo KS +17 more
europepmc +3 more sources
Systematic Review and Meta-Analysis of Seasonal Malaria Chemoprevention. [PDF]
ABSTRACT. Seasonal malaria chemoprevention (SMC) for children under 5 years of age for up to four monthly cycles during malaria transmission season was recommended by the WHO in 2012 and has been implemented in 13 countries in the Sahel, reaching more than 30 million children annually.
Thwing J +3 more
europepmc +3 more sources

