Results 71 to 80 of about 5,985 (143)

Effectiveness of seasonal malaria chemoprevention at scale in west and central Africa: an observational study [PDF]

The Lancet, 2020
Seasonal malaria chemoprevention (SMC) aims to prevent malaria in children during the high malaria transmission season. The Achieving Catalytic Expansion of SMC in the Sahel (ACCESS-SMC) project sought to remove barriers to the scale-up of SMC in seven countries in 2015 and 2016.
Jean-Bosco Ouédraogo, Mamadou Chérif Traore, Timothee Guilavogui, Matt Coldiron, Godwin Ntadom, Adama Sanogo, Patrice Coulibaly, Halimatou Alassana Messan, Yolanda Fernandez, Bala Audu, Sham Lal, Hamit Kesseley, Julian Muwanguzi, Musa Abubakar Kana, Nadine Ngarnaye, Markieu Janneh Kaira, Harriet Kivumbi, Joanna Stenstrom Johansson, Ebenezer Baba, Balla Kandeh, Kodbesse Boulotigam, Maddy Marasciulo, Eugene Kaman Lama, Raoul Mansukhani, Kolawole Maxwell, Suzanne Van Hulle, Sonny Johnbull Ogboi, Jane Achan, David Collins, Eric Hubbard, Mariama Sire Sano, Fatou Jah, Shanthi N. Pal, Ibrahim Laminou, Serign J. Ceesay, Khalid B. Beshir, Abdoulaye Djimde, Arantxa Roca-Feltrer, Paul Milligan, André-Marie Tchouatieu, Prudence Hamade, Diakalidia Kone, Noha Iessa, Christine M Halleux, Issaka Zongo, Paul Snell, Kovana Marcel Loua, Alassane Dicko, Issaka Sagara, Yacouba Savodogo, Yacine Djibo, Moussa Keita, Rhosyn Tuta, Gladys Tetteh, Daugla Doumagoum, Djiddi Ali Sougoudi, Susana Scott, Matthew Cairns, Hadiza Jackou, Corinne Merle, Momodou Kalleh, James K Tibenderana, Fara Ndiaye, Alice Kiba, Colin J. Sutherland, Aishatu Yinusa Cassandra Elagbaje, George Jagoe, Colin Gilmartin, Houda Sefiani, Tony Eloike, Jean Louis NdDiaye, Ibrahim Ouba, Rahila Abdoulaye, Diego Moroso, Rachida Souleymani, Abdoulaye Hama Diallo, Huja Jah, Emile Ouedraogo, Rebecca F. Grais, Kalifa Bojang, Lantorina Razafindralambo   +80 more
openaire   +3 more sources

Estimating the potential public health impact of seasonal malaria chemoprevention in African children [PDF]

Nature Communications, 2012
Seasonal malaria chemoprevention, previously known as intermittent preventive treatment in children, is highly effective in areas with a short malaria transmission season. Here we assess seasonality in malaria incidence data and define a predictor of seasonality based on rainfall.
Brian Greenwood, Azra C. Ghani, Arantxa Roca-Feltrer, Arantxa Roca-Feltrer, Tini Garske, Diadier Diallo, Anne L. Wilson, Matthew Cairns, Paul Milligan   +8 more
openaire   +8 more sources

Effect of routine seasonal malaria chemoprevention on malaria trends in children under 5 years in Dangassa, Mali [PDF]

Malaria Journal, 2020
Abstract Background Seasonal malaria chemoprevention (SMC) is a new strategy to prevent malaria in children under 5 years old. It has been recommended by the World Health Organization since 2012 in malaria-endemic areas with seasonal transmission. This study aimed to assess the changes in malaria indicators through two consecutive years of SMC routine ...
Mahamoudou B. Touré, Nafomon Sogoba, Sibe Thiam, Seydou Doumbia, Bourama Keita, Ibrahim Sissoko, Sekou F. Traore, Seidina A. S. Diakite, Ayouba Diarra, Karim Traore, Moussa Keita, Agnès Guindo, Drissa Konaté, Mahamadou Diakite, Sory I. Diawara, Donald J. Krogtad   +15 more
openaire   +4 more sources

Increasing the uptake of Intermittent Preventive Treatment of malaria in pregnancy using Sulfadoxine-Pyrimethamine (IPTp-SP) through seasonal malaria chemoprevention channel delivery: protocol of a multicenter cluster randomized implementation trial in Mali and Burkina Faso

BMC Public Health
Background The uptake of Intermittent Preventive Treatment of malaria in pregnancy using Sulfadoxine-Pyrimethamine (IPTp-SP) remains unacceptably low, with more than two-thirds of pregnant women in sub-Saharan Africa still not accessing the three or more
Kadiatou Koita, J. Bognini, E. Agboraw, Mahamadou Dembélé, Seydou Yabré, Biébo Bihoun, Oumou Coulibaly, H. Niangaly, Jean-Batiste N’Takpé, M. Lesosky, Dario Scaramuzzi, E. Worrall, Jenny Hill, Valérie Briand, H. Tinto, K. Kayentao   +15 more
semanticscholar   +1 more source

Review of contextual factors related to seasonal malaria chemoprevention

, 2022
Report considered by the WHO/GMP Guideline Development Group on Malaria Chemoprevention for “Section 4.2.3 Seasonal malaria chemoprevention (SMC)” of the WHO Guidelines for malaria, 3 June 2022.
Bhattarai A, Thwing J, Williamson J, Cavros I, Gutman J   +4 more
openaire   +2 more sources

Opportunities and Challenges of Population Pharmacogenomics

Annals of Human Genetics, Volume 89, Issue 5, Page 384-397, September 2025.
ABSTRACT Pharmacological responses can vary significantly among patients from different ethnogeographic backgrounds. This variability can, at least in part, be attributed to population‐specific genetic patterns in genes involved in drug absorption, distribution, metabolism, and excretion, as well as in genes associated with drug‐induced toxicity ...
Yitian Zhou, Yoomi Park, Mahamadou D. Camara, Volker M. Lauschke   +3 more
wiley   +1 more source

Acceptability by community health workers in Senegal of combining community case management of malaria and seasonal malaria chemoprevention [PDF]

Malaria Journal, 2013
Community case management of malaria (CCMm) and seasonal malaria chemoprevention (SMC) are anti-malarial interventions that can lead to substantial reduction in malaria burden acting in synergy. However, little is known about the social acceptability of these interventions.
Tine, Roger Ck, Ndiaye, Pascal, Ndour, Cheikh T, Faye, Babacar, Ndiaye, Jean L, Sylla, Khadime, Ndiaye, Magatte, Cisse, Badara, Sow, Doudou, Magnussen, Pascal, Bygbjerg, Ib C, Gaye, Oumar   +11 more
openaire   +4 more sources

Use of population pharmacokinetic‐pharmacodynamic modelling to inform antimalarial dose optimization in infants

British Journal of Clinical Pharmacology, Volume 91, Issue 4, Page 968-980, April 2025.
Infants bear a significant malaria burden but are usually excluded from participating in early dose optimization studies that inform dosing regimens of antimalarial therapy. Unlike older children, infants' exclusion from early‐phase trials has resulted in limited evidence to guide accurate dosing of antimalarial treatment for uncomplicated malaria or ...
Clifford G. Banda, Joel Tarning, Karen I. Barnes   +2 more
wiley   +1 more source

Seasonal Malaria Chemoprevention: An Evolving Research Paradigm

PLOS Medicine, 2016
Robert W. Snow discute de l'importance des preuves empiriques, telles que celles fournies dans l'essai publié cette semaine par Milligan et ses collègues, pour guider la lutte contre le paludisme en Afrique.
Robert W. Snow, Robert W. Snow
openaire   +4 more sources

Effectiveness of seasonal malaria chemoprevention in reducing under-five malaria morbidity and mortality in the Savannah Region, Ghana

Ghana Medical Journal, 2022
Objective: To assess the effectiveness of seasonal malaria chemoprevention (SMC) in reducing under-five malaria morbidity and mortalityDesign: Under-five malaria data for confirmed episodes, deaths, and number of children dosed per cycle of SMC campaign were extracted from the District Health Information Management System (DHIMS-2) for 2018-2019.
R Adjei, Michael, Kubio, Chrysantus, Buamah, Marcel, Sarfo, Adjei, Suuri, Thomas, Ibrahim, Saeed, Sadiq, Abubakari, I Abubakari, Ihsan, V Baafi, Janet   +8 more
openaire   +3 more sources