Results 71 to 80 of about 3,965 (238)

Barriers to uptake and implementation of malaria chemoprevention in school-aged children: a stakeholder engagement meeting report

open access: yesFrontiers in Tropical Diseases
Malaria is a leading cause of death in school-aged children in sub-Saharan Africa, and non-fatal chronic malaria infections are associated with anaemia, school absence and decreased learning, preventing children from reaching their full potential ...
Colette Morlino   +44 more
doaj   +1 more source

Implementation strategies for the introduction of the RTS,S/AS01 (RTS,S) malaria vaccine in countries with areas of highly seasonal transmission: workshop meeting report

open access: yesMalaria Journal, 2023
A workshop on implementation strategies for the introduction of the RTS,S/AS01 (RTS,S) malaria vaccine in countries with areas of highly seasonal transmission, was held as a hybrid meeting in Dakar, Senegal, and online, 23–25 January 2023. Delegates from
Corinne S. Merle, RTSS-SMC working group
doaj   +1 more source

Seasonal malaria vaccination: protocol of a phase 3 trial of seasonal vaccination with the RTS,S/AS01Evaccine, seasonal malaria chemoprevention and the combination of vaccination and chemoprevention

open access: yesBMJ Open, 2020
IntroductionSeasonal malaria chemoprevention (SMC), with sulphadoxine–pyrimethamine plus amodiaquine (SP+AQ) is effective but does not provide complete protection against clinical malaria. The RTS,S/AS01Emalaria vaccine provides a high level of protection shortly after vaccination, but this wanes rapidly.
Ismaila Thera   +18 more
openaire   +3 more sources

Impact of seasonal malaria chemoprevention on hospital admissions and mortality in children under 5 years of age in Ouelessebougou, Mali

open access: yesMalaria Journal, 2020
Background Seasonal malaria chemoprevention is widely implemented in Sahel and sub-Sahel countries in Africa. Few studies have assessed the impact of the SMC on hospital admission and death when it is implemented in the health system.
Djibrilla Issiaka   +9 more
doaj   +1 more source

Malaria intervention scale-up in Africa : effectiveness predictions for health programme planning tools, based on dynamic transmission modelling [PDF]

open access: yes, 2016
Scale-up of malaria prevention and treatment needs to continue to further important gains made in the past decade, but national strategies and budget allocations are not always evidence-based.
Briët, Olivier J. T.   +7 more
core   +6 more sources

Effect of Seasonal Malaria Chemoprevention on Immune Markers of Exhaustion and Regulation [PDF]

open access: yesThe Journal of Infectious Diseases, 2019
Abstract Background Seasonal malaria chemoprevention (SMC) is a novel strategy to reduce malaria infections in children. Infection with Plasmodium falciparum results in immune dysfunction characterized by elevated expression of markers associated with exhaustion, such as PD1 and LAG3, and regulatory ...
Oumar, Attaher   +18 more
openaire   +2 more sources

Sub-national tailoring of seasonal malaria chemoprevention in Mali based on malaria surveillance and rainfall data

open access: yesParasites & Vectors, 2022
Abstract Background In malaria endemic countries, seasonal malaria chemoprevention (SMC) interventions are performed during the high malaria transmission in accordance with epidemiological surveillance data. In this study we propose a predictive approach for tailoring the timing and number of cycles of SMC in all health ...
Cissoko, Mady   +15 more
openaire   +4 more sources

Evidence that seasonal malaria chemoprevention with SPAQ influences blood and pre-erythrocytic stage antibody responses of Plasmodium falciparum infections in Niger

open access: yesMalaria Journal, 2021
Background In endemic areas, children develop slowly and naturally anti-Plasmodium antibodies and become semi-immune. Seasonal Malaria Chemoprevention (SMC) with sulfadoxine-pyrimethamine + amodiaquine (SPAQ) is a new strategy to reduce malaria morbidity
Lamine Mahaman Moustapha   +7 more
doaj   +1 more source

Impact of a malaria intervention package in schools on Plasmodium infection, anaemia and cognitive function in schoolchildren in Mali: a pragmatic cluster-randomised trial. [PDF]

open access: yes, 2017
BACKGROUND: School-aged children are rarely targeted by malaria control programmes, yet the prevalence of Plasmodium infection in primary school children often exceeds that seen in younger children and could affect haemoglobin concentration and school ...
Bamadio, Modibo   +12 more
core   +4 more sources

Cost-effectiveness of seasonal malaria chemoprevention in upper west region of Ghana [PDF]

open access: yesMalaria Journal, 2016
In Ghana, malaria is endemic and perennial (with significant seasonal variations in the three Northern Regions), accounting for 33 % of all deaths among children under 5 years old, with prevalence rates in children under-five ranging from 11 % in Greater Accra to 40 % in Northern Region.
Nonvignon, Justice   +8 more
openaire   +2 more sources

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