Results 81 to 90 of about 1,896 (179)
Objective: To assess the effectiveness of seasonal malaria chemoprevention (SMC) in reducing under-five malaria morbidity and mortalityDesign: Under-five malaria data for confirmed episodes, deaths, and number of children dosed per cycle of SMC campaign were extracted from the District Health Information Management System (DHIMS-2) for 2018-2019.
R Adjei, Michael+8 more
openaire +3 more sources
Gametocyte carriage after seasonal malaria chemoprevention in Plasmodium falciparum infected asymptomatic children [PDF]
Abstract Background Treatment of clinical Plasmodium falciparum malaria with sulfadoxine-pyrimethamine (SP) and amodiaquine (AQ) is associated with increased post-treatment gametocyte carriage. The effect of seasonal malaria chemoprevention (SMC) with SP and AQ on gametocyte carriage was assessed in asymptomatic P ...
Abdullahi Ahmad+11 more
openaire +8 more sources
Infants bear a significant malaria burden but are usually excluded from participating in early dose optimization studies that inform dosing regimens of antimalarial therapy. Unlike older children, infants' exclusion from early‐phase trials has resulted in limited evidence to guide accurate dosing of antimalarial treatment for uncomplicated malaria or ...
Clifford G. Banda+2 more
wiley +1 more source
Background Seasonal malaria chemoprevention (SMC) involves administering antimalarial drugs at monthly intervals during the high malaria transmission period to children aged 3 to 59 months as recommended by the World Health Organization.
Adama Traore+10 more
doaj +1 more source
ABSTRACT Piperaquine tetraphosphate (PQP), a long‐acting antimalarial, is being considered in a combination for chemoprevention. Dihydroartemisinin‐piperaquine tablets (hard and dispersible) approved for the treatment of acute uncomplicated malaria should be administered in a fasted state, as PQP bioavailability increases with food.
Florence A. Milando+31 more
wiley +1 more source
Population impact of malaria control interventions in the health district of Kati, Mali.
BackgroundWHO and its partners have adopted alternative control interventions since the failure to eradicate malaria worldwide in the 1960s and 1970s.
Abdoulaye Katile+10 more
doaj +1 more source
Prioritizing the scale-up of interventions for malaria control and elimination
Background A core set of intervention and treatment options are recommended by the World Health Organization for use against falciparum malaria. These are treatment, long-lasting insecticide-treated bed nets, indoor residual spraying, and chemoprevention
Peter Winskill+3 more
doaj +1 more source
Artesunate–amodiaquine (ARS–AQ) is a first‐line antimalarial treatment recommended by the World Health Organization. AQ is the long acting partner drug in this combination, and therapeutic success is correlated with the terminal exposure to AQ. Dried blood spot (DBS) sampling for AQ is a convenient and minimally invasive technique, especially suitable ...
Natpapat Kaewkhao+3 more
wiley +1 more source
Making the most of malaria chemoprevention
Against a backdrop of stalled progress in malaria control, it is surprising that the various forms of malaria chemoprevention are not more widely used. The World Health Organization (WHO) has recommended several malaria chemoprevention strategies, some ...
Jasper Littmann+4 more
doaj +1 more source
Background: Malaria is one of the deadliest mosquito‐borne diseases. Despite the demonstrated benefits of insecticide‐treated nets (ITNs) usage in children under 5 years of age, nonuse is linked to higher mortality and morbidity rates. This study examined how child‐, maternal‐, household‐, and community‐level determinants influence ITN utilization ...
Amadou Barrow+7 more
wiley +1 more source