Impact of a malaria intervention package in schools on Plasmodium infection, anaemia and cognitive function in schoolchildren in Mali: a pragmatic cluster-randomised trial. [PDF]
BACKGROUND: School-aged children are rarely targeted by malaria control programmes, yet the prevalence of Plasmodium infection in primary school children often exceeds that seen in younger children and could affect haemoglobin concentration and school ...
Bamadio, Modibo +12 more
core +3 more sources
Globally nearly 40% of children under 5 years old are anaemic, which affects their ability to grow and develop. A cluster randomised trial was conducted in 60 communities in Southern Mali to evaluate the added impact of home fortification with micronutrient powders, delivered alongside seasonal malaria chemoprevention, on anaemia, malaria infection ...
Niélé H. Diarra +18 more
wiley +1 more source
Review of contextual factors related to seasonal malaria chemoprevention
Report considered by the WHO/GMP Guideline Development Group on Malaria Chemoprevention for “Section 4.2.3 Seasonal malaria chemoprevention (SMC)” of the WHO Guidelines for malaria, 3 June 2022.
Bhattarai A +4 more
openaire +1 more source
Abstract Background SMC was adopted in Nigeria in 2014 and by 2021 was being implemented in 18 states, over four months between June and October by 143000 community drug distributors (CDDs) to a target population of 23million children.
Nnenna Ogbulafor +16 more
openaire +3 more sources
Tools and Strategies for Malaria Control and Elimination: What Do We Need to Achieve a Grand Convergence in Malaria? [PDF]
Progress made in malaria control during the past decade has prompted increasing global dialogue on malaria elimination and eradication. The product development pipeline for malaria has never been stronger, with promising new tools to detect, treat, and ...
Achee, Nicole +6 more
core +3 more sources
Opportunities and Challenges of Population Pharmacogenomics
ABSTRACT Pharmacological responses can vary significantly among patients from different ethnogeographic backgrounds. This variability can, at least in part, be attributed to population‐specific genetic patterns in genes involved in drug absorption, distribution, metabolism, and excretion, as well as in genes associated with drug‐induced toxicity ...
Yitian Zhou +3 more
wiley +1 more source
Infants bear a significant malaria burden but are usually excluded from participating in early dose optimization studies that inform dosing regimens of antimalarial therapy. Unlike older children, infants' exclusion from early‐phase trials has resulted in limited evidence to guide accurate dosing of antimalarial treatment for uncomplicated malaria or ...
Clifford G. Banda +2 more
wiley +1 more source
Sub-National Targeting of Seasonal Malaria Chemoprevention in the Sahelian Countries of the Nouakchott Initiative [PDF]
Antecedentes Se ha demostrado que la quimioprevención estacional de la malaria (SMC) es altamente eficaz contra la malaria clínica en áreas donde la transmisión es agudamente estacional. La focalización de SMC depende de una interacción compleja del clima, la transmisión de la malaria y la distribución de la población.
Abdisalan M. Noor +5 more
openaire +4 more sources
Background Seasonal malaria chemoprevention (SMC) is a new strategy to reduce malaria burden in young children in Sahelian countries. It consists of the administration of full treatment courses of sulfadoxine–pyrimethamine plus amodiaquine to children at
Almahamoudou Mahamar +12 more
doaj +1 more source
Feasibility and Coverage of Implementing Intermittent Preventive Treatment of Malaria in Pregnant women Contacting Private or Public Clinics in Tanzania: Experience-based Viewpoints of Health Managers in Mkuranga and Mufindi districts. [PDF]
Evidence on healthcare managers' experience on operational feasibility of malaria intermittent preventive treatment for malaria during pregnancy (IPTp) using sulphadoxine-pyrimethamine (SP) in Africa is systematically inadequate.
A Hughes +56 more
core +1 more source

