Results 81 to 90 of about 3,965 (238)

Review of contextual factors related to seasonal malaria chemoprevention

open access: yes, 2022
Report considered by the WHO/GMP Guideline Development Group on Malaria Chemoprevention for “Section 4.2.3 Seasonal malaria chemoprevention (SMC)” of the WHO Guidelines for malaria, 3 June 2022.
Bhattarai A   +4 more
openaire   +1 more source

Associations Between Climate‐Sensitive Nutrients, Clinical Malaria, and Anaemia Among Young Children in Rural Burkina Faso: An Analysis of Baseline Data From a Cluster‐Randomised Controlled Trial

open access: yesTropical Medicine &International Health, Volume 31, Issue 2, Page 181-189, February 2026.
ABSTRACT Objective Malaria and anaemia are significant public health challenges among young children in Burkina Faso, with complex interactions between climate variability, food security, and nutrient deficiencies. This study aimed to identify the malariometric profile and nutrient patterns among young children and to determine the associations of ...
Adi Lukas Kurniawan   +8 more
wiley   +1 more source

Nutritional status in young children prior to the malaria transmission season in Burkina Faso and Mali, and its impact on the incidence of clinical malaria

open access: yesMalaria Journal, 2021
Background Malaria and malnutrition remain major problems in Sahel countries, especially in young children. The direct effect of malnutrition on malaria remains poorly understood, and may have important implications for malaria control.
Mariken de Wit   +18 more
doaj   +1 more source

Micronutrient Powders Combined With Malaria Chemoprevention to Improve Anaemia and Cognitive Function in Early Childhood in Mali: A Cluster‐Randomised Trial

open access: yesMaternal &Child Nutrition, Volume 21, Issue 4, October 2025.
Globally nearly 40% of children under 5 years old are anaemic, which affects their ability to grow and develop. A cluster randomised trial was conducted in 60 communities in Southern Mali to evaluate the added impact of home fortification with micronutrient powders, delivered alongside seasonal malaria chemoprevention, on anaemia, malaria infection ...
Niélé H. Diarra   +18 more
wiley   +1 more source

A proposed method of grading malaria chemoprevention efficacy [PDF]

open access: yes, 2023
The efficacy and effectiveness of antimalarial drugs are threatened by increasing levels of resistance and therefore require continuous monitoring. Chemoprevention is increasingly deployed as a malaria control measure, but there are no generally accepted
Bonnington, C, Nosten, Fh, White, NJ
core   +2 more sources

Opportunities and Challenges of Population Pharmacogenomics

open access: yesAnnals of Human Genetics, Volume 89, Issue 5, Page 384-397, September 2025.
ABSTRACT Pharmacological responses can vary significantly among patients from different ethnogeographic backgrounds. This variability can, at least in part, be attributed to population‐specific genetic patterns in genes involved in drug absorption, distribution, metabolism, and excretion, as well as in genes associated with drug‐induced toxicity ...
Yitian Zhou   +3 more
wiley   +1 more source

Effectiveness of seasonal malaria chemoprevention in three regions of Togo: a population-based longitudinal study from 2013 to 2020

open access: yesMalaria Journal, 2022
Background In 2012, the World Health Organization (WHO) recommended seasonal malaria chemoprevention (SMC) in areas of high seasonal transmission. Though implemented since 2013, the effectiveness of SMC in Togo was never evaluated.
Tchaa A. Bakai   +7 more
doaj   +1 more source

Use of population pharmacokinetic‐pharmacodynamic modelling to inform antimalarial dose optimization in infants

open access: yesBritish Journal of Clinical Pharmacology, Volume 91, Issue 4, Page 968-980, April 2025.
Infants bear a significant malaria burden but are usually excluded from participating in early dose optimization studies that inform dosing regimens of antimalarial therapy. Unlike older children, infants' exclusion from early‐phase trials has resulted in limited evidence to guide accurate dosing of antimalarial treatment for uncomplicated malaria or ...
Clifford G. Banda   +2 more
wiley   +1 more source

Effect of seasonal malaria chemoprevention on the acquisition of antibodies to Plasmodium falciparum antigens in Ouelessebougou, Mali

open access: yesMalaria Journal, 2017
Background Seasonal malaria chemoprevention (SMC) is a new strategy to reduce malaria burden in young children in Sahelian countries. It consists of the administration of full treatment courses of sulfadoxine–pyrimethamine plus amodiaquine to children at
Almahamoudou Mahamar   +12 more
doaj   +1 more source

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