Results 81 to 90 of about 3,433 (163)

Bioactive Phytochemical Compounds in Medicago sativa L. (Alfalfa): A Systematic Review of Biological Properties and Therapeutic Relevance in Nutraceutical and Functional Food Implications

Food Frontiers, Volume 7, Issue 2, March 2026.
ABSTRACT Medicago sativa L. (alfalfa) harbors a remarkably diverse reservoir of bioactive secondary metabolites. Flavonoids, isoflavones, and triterpenoid saponins dominate its bioactivity landscape, driving potent antioxidant, anti‐inflammatory, antimicrobial, estrogenic, hypolipidemic, and cytotoxic actions through redox modulation, membrane ...
Parham Joolaei Ahranjani, Hamid Rashidi Nodeh, Zahra Esfandiari, Giovanna Ferrentino   +3 more
wiley   +1 more source

Performance and egg quality of laying hens fed flaxseed: highlights on n-3 fatty acids, cholesterol, lignans and isoflavones

Animal, 2017
Flaxseed is a rich source of α-linolenic acid and phytoestrogens, mainly lignans, whose metabolites (enterodiol and enterolactone) can affect estrogen functions.
S. Mattioli, S. Ruggeri, B. Sebastiani, G. Brecchia, A. Dal Bosco, A. Cartoni Mancinelli, C. Castellini   +6 more
doaj   +1 more source

Revealing the Mammalian Lignan Precursor Secoisolariciresinol Diglucoside in Flaxseed by Ionspray Mass Spectrometry

, 1994
Ionspray mass spectrometry allowed the rapid detection and unambiguous identification of secoisolariciresinol diglucoside, an important mammalian lignan precursor occurring in flax seed.
Valerio Giannellini, Massimo BambagiottiAlberti, Silvia A Coran, Caterina Ghiara, Andrea Raffaelli   +4 more
core  

Role of bifidobacteria in the activation of the lignan secoisolariciresinol diglucoside

, 2011
Lignans are ubiquitous plant polyphenols, which have relevant healthy properties, being the major phytoestrogens occurring in western diets. Secoisolariciresinol (SECO) is the major dietary lignan, mostly found in plants as secoisolariciresinol ...
LEONARDI, Alan, Stefano Raimondi, ROSSI, Maddalena, Alberto Amaretti, Alan Leonardi, Maddalena Rossi, L. Roncaglia, AMARETTI, Alberto, RAIMONDI, Stefano, Lucia Roncaglia   +9 more
core   +1 more source

Secoisolariciresinol diglucoside abrogates oxidative stress-induced damage in cardiac iron overload condition.

PLoS ONE, 2015
Cardiac iron overload is directly associated with cardiac dysfunction and can ultimately lead to heart failure. This study examined the effect of secoisolariciresinol diglucoside (SDG), a component of flaxseed, on iron overload induced cardiac damage by ...
Stephanie Puukila, Sean Bryan, Anna Laakso, Jessica Abdel-Malak, Carli Gurney, Adrian Agostino, Adriane Belló-Klein, Kailash Prasad, Neelam Khaper   +8 more
doaj   +1 more source

Development of antibodies against secoisolariciresinol – Application to the immunolocalization of lignans in Linum usitatissimum seeds

, 2010
International audienceLignans are widely distributed plant metabolites associated with a large range of biological activities In order to gain insight into their biosynthesis and their spatio-temporal accumulation an immunological probe was developed ...
Marc-André Fliniaux, Christophe Bienaimé, Bienaimé, Christophe, Dubois, Frédéric, Frédéric Dubois, Attoumbre, Jacques, Fliniaux, Marc-André, Jacques Attoumbré, Sylvie Baltora-Rosset, Chabbert, Brigitte, Baltora-Rosset, Sylvie, Brigitte Chabbert   +11 more
core   +1 more source

Kinetics of Secoisolariciresinol Glucosyltransferase LuUGT74S1 and Its Mutants

The lignan secoisolariciresinol (SECO) diglucoside (SDG) is a phytoestrogen with diverse effects. LuUGT74S1 glucosylates SECO to SDG, whereby only small amounts of the monoglucoside SMG are formed intermediately, which exhibit increased activity.
Schwab, Wilfried, Moree, Sadiq Saleh, Böhm, Lukas, Hoffmann, Thomas   +3 more
core   +1 more source

Intake of the plant lignans secoisolariciresinol, matairesinol, lariciresinol and pinoresinol in Dutch men and women

, 2005
Enterolignans (enterolactone and enterodiol) are phytoestrogens that are formed by the colonic microflora from plant lignans. They may reduce the risk of certain types of cancer and cardiovascular diseases.
Arts, I.C.W., Feskens, E.J.M., Kromhout, D., Milder, I.E.J., Bueno de Mesquita, H.B., Hollman, P.C.H.   +5 more
core   +1 more source

Secoisolariciresinol diglucoside is a blood-brain barrier protective and anti-inflammatory agent: implications for neuroinflammation

Journal of Neuroinflammation, 2018
Background Secoisolariciresinol diglucoside (SDG), the main lignan in flaxseed, is known for its beneficial effects in inflammation, oxidative stress, heart disease, tumor progression, atherosclerosis, and diabetes.
Slava Rom, Viviana Zuluaga-Ramirez, Nancy L. Reichenbach, Michelle A. Erickson, Malika Winfield, Sachin Gajghate, Melpo Christofidou-Solomidou, Kelly L. Jordan-Sciutto, Yuri Persidsky   +8 more
doaj   +1 more source

Potential Target Metabolites From Gut Microbiota Against Hepatocellular Carcinoma: A Network Pharmacology and Molecular Docking Study

International Journal of Microbiology
Hepatocellular carcinoma (HCC) is a leading cause of cancer-related deaths worldwide, posing significant challenges and economic burdens on healthcare systems.
Sehar Aslam, Muhammad Qasim, Fatima Noor, Muhammad Shahid, Usman Ali Ashfaq, Samman Munir, Helal F. Al-Harthi, Mutaib M. Mashraqi, Umair Waqas, Mohsin Khurshid   +9 more
doaj   +1 more source