Results 21 to 30 of about 2,867 (139)

Secoisolariciresinol Diglucoside with Antioxidant Capacity from Flaxseed: A Study on Microwave-Assisted Germination Optimization [PDF]

Foods
Germination and physical field treatments are processing techniques that have been successfully used to change the amount of active ingredients in flaxseed. However, it is unknown if they work synergistically.
Jinling Hu, Qingyi Zhang, Yaning Li, Qiqi Zhang, Caihua Jia, Fenghong Huang, Qianchun Deng, Cuie Tang   +7 more
doaj   +2 more sources

MODIFICATION OF LIGNANS BY TRAMETES HIRSUTA LACCASE [PDF]

BioResources, 2009
Oxidative polymerization of two isolated lignans, secoisolariciresinol, and secoisolariciresinol diglucoside, as well as the lignan macromolecule, by a high redox potential Trametes hirsuta laccase was studied with different analytical methods.
Maija-Liisa Mattinen, Karin Struijs, Tapani Suortti, Ismo Mattila, Kristiina Kruus, Stefan Willför, Tarja Tamminen, Jean-Paul Vincken   +7 more
doaj   +5 more sources

Secoisolariciresinol Diglucoside Regulates Adipose Tissue Metabolic Disorder in Obese Mice Induced by a Western Diet

Journal of Food Quality, 2021
Secoisolariciresinol diglucoside (SDG) is the main component of flax lignans. Current studies have reported a positive effect of SDG on obesity and metabolic diseases. SDG has strong blood fat- and blood sugar-lowering, anti-inflammatory, and antioxidant
Shan Dong, Wenliang Bai, Jiaping Chen, Li Zhang, Wanli Sheng, Ronghu Feng   +5 more
doaj   +2 more sources

Successful Outcome of a Patient with Concomitant Pancreatic and Renal Carcinoma Receiving Secoisolariciresinol Diglucoside Therapy Alone: A Case Report [PDF]

International Medical Case Reports Journal
Hao Wu,1– 6 Xing-Hua Zhang,1,3– 6 Li-Ping Wang,7,8 Hong-Da Tian,1,3– 6 Gui-Rong Liu,1,3– 6 Dong-Hui Yang,9 Shu-Lin Liu1,3– 8,10 1Genomics Research Center (State-Province Key Laboratory of Biomedicine-Pharmaceutics of China), College of Pharmacy, Harbin ...
Wu H, Zhang XH, Wang LP, Tian HD, Liu GR, Yang DH, Liu SL   +6 more
doaj   +2 more sources

The Synthetic Lignan Secoisolariciresinol Diglucoside Prevents Asbestos-Induced NLRP3 Inflammasome Activation in Murine Macrophages. [PDF]

Oxid Med Cell Longev, 2017
Background. The interaction of asbestos with macrophages drives two key processes that are linked to malignancy: (1) the generation of reactive oxygen species (ROS)/reactive nitrogen species (RNS) and (2) the activation of an inflammation cascade that ...
Pietrofesa RA, Woodruff P, Hwang WT, Patel P, Chatterjee S, Albelda SM, Christofidou-Solomidou M.   +6 more
europepmc   +2 more sources

Lignans Associated Differences in Salt Stress Responses of Flax (Linum usitatissimum L.) Genotypes In Vitro [PDF]

Cells
The objective of this study was to investigate the association between lignan content and stress responses in flax genotypes with contrasting lignan levels.
Moumita Roy Chowdhury, Katarína Ražná, Jindra Valentová, Emil Švajdlenka, Eva Ivanišová, Anirban Jyoti Debnath, Jit Mukherjee, Veronika Štefúnová, Mizgin Mehmet, Paračková Patrícia, Marián Miko   +10 more
doaj   +2 more sources

Secoisolariciresinol diglucoside attenuates neuroinflammation and cognitive impairment in female Alzheimer’s disease mice via modulating gut microbiota metabolism and GPER/CREB/BDNF pathway [PDF]

Journal of Neuroinflammation
Background Gender is a significant risk factor for late-onset Alzheimer’s disease (AD), often attributed to the decline of estrogen. The plant estrogen secoisolariciresinol diglucoside (SDG) has demonstrated anti-inflammatory and neuroprotective effects.
Mengzhen Jia, Fangjie Ning, Junqing Wen, Xiaorui Wang, Jiao Chen, Jun Hu, Xuhui Chen, Zhigang Liu   +7 more
doaj   +2 more sources

Molecular Mechanisms of Lignans in Lowering Blood Pressure and Anti-Obesity Effects: A Review [PDF]

Foods
Lignans are naturally occurring compounds found in a wide variety of plant species, including flaxseed, soybean, pumpkin seed, broccoli, sesame seed, and some berries.
Gitishree Das, Sandra Gonçalves, José Basilio Heredia, Nayely Leyva-López, Anabela Romano, Spiros Paramithiotis, Han-Seung Shin, Jayanta Kumar Patra   +7 more
doaj   +2 more sources

Induced Mutagenesis in UGT74S1 Gene Leads to Stable New Flax Lines with Altered Secoisolariciresinol Diglucoside (SDG) Profiles [PDF]

Frontiers in Plant Science, 2017
Flax secoisolariciresinol (SECO) diglucoside (SDG) lignan is an emerging natural product purported to prevent chronic diseases in humans. SECO, the aglycone form of SDG, has shown higher intestinal cell absorption but it is not accumulated naturally in ...
Bourlaye Fofana, Kaushik Ghose, Ashok Somalraju, Jason McCallum, David Main, Michael K. Deyholos, Gordon G. Rowland, Sylvie Cloutier   +7 more
doaj   +2 more sources

The Flaxseed-Derived Lignan Phenolic Secoisolariciresinol Diglucoside (SDG) Protects Non-Malignant Lung Cells from Radiation Damage. [PDF]

Int J Mol Sci, 2015
Plant phenolic compounds are common dietary antioxidants that possess antioxidant and anti-inflammatory properties. Flaxseed (FS) has been reported to be radioprotective in murine models of oxidative lung damage.
Velalopoulou A, Tyagi S, Pietrofesa RA, Arguiri E, Christofidou-Solomidou M.   +4 more
europepmc   +2 more sources