Results 61 to 70 of about 10,830,518 (287)

Emerging experimental and computational methods for studying redox‐regulated structural transitions

open access: yesFEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass   +2 more
wiley   +1 more source

Second Language Writing Ability: Towards a Complete Construct Definition

open access: yesStudies in Applied Linguistics & TESOL, 2006
In this paper, I explore the construct of second language (L2) writing ability within the context of large-scale writing assessment. As L2 writing theory is based in part on the previously established field of first language (L1) writing, I provide a ...
Kristen di Gennaro
doaj   +1 more source

Language Scaffolding in Second Language Writing

open access: yesThe CATESOL Journal, 2007
This paper explores a kind of language instruction that facilitates student writers’ learning of grammar skills through providing a carefully constructed supportive framework—language scaffolding. To illustrate, a five-step pedagogy for scaffolded instruction is proposed, including contextual-awareness building, model analysis, controlled and guided ...
openaire   +3 more sources

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

open access: yesFEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav   +2 more
wiley   +1 more source

Exploring a sociocultural approach to writing strategy research: mediated actions in writing activities

open access: yes, 2008
In contrast to the traditional cognitive view of writing strategies, this study explores English as a foreign language (EFL) learners' writing strategy use within the Activity Theory framework, adding to the growing body of writing strategy research and ...
Lei, X
core   +1 more source

A Study of Language Socialization: Learning and Making Sense in a Second Language Classroom [PDF]

open access: yes, 1997
This paper is about children's second language socialization. It is about how a child, a Japanese eight year old boy, tries to make sense of his world in a second language classroom.
Jasso-Aguilar, Rebeca
core   +1 more source

Second language writing instruction: A recent practice in Indonesia

open access: yesScript Journal, 2018
Today, a majority of people appear to agree that with the rapid development of English, writing skills cannot be isolated as a standout amongst the most critical skills ((Ali & Hasanah, 2014; Asrifan, 2015). Mustafa and Samad (2015, p. 32) identified two
Elsa Widya Hapsari   +1 more
doaj   +1 more source

Prospecting the protein design landscape

open access: yesFEBS Letters, EarlyView.
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona   +4 more
wiley   +1 more source

A cognitive meta-linguistic approach to teaching English information structure for the development of communicative language ability among learners of English as a second language

open access: yes, 2011
In the realization that second language learners’ grammatical competence does not always guarantee their communicative language ability and that meta-knowledge of English information structure might play an important role in developing their ...
Huynh, Tuan Anh
core   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

open access: yesMolecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura   +19 more
wiley   +1 more source

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