Results 201 to 210 of about 272,599 (253)

Rhythms in Second Messenger Mechanisms

Pharmacology & Therapeutics, 1991
In this chapter circadian rhythms in the beta-adrenoceptor/adenylate cyclase/phosphodiesterase system are presented and discussed. Daily variation in total number and affinity of beta-adrenoceptors in rat forebrain and rat heart ventricles seem to be of minor importance in the circadian regulation of the cAMP concentration in these tissues.
K, Witte, B, Lemmer
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A second look at the second messenger hypothesis

Life Sciences, 1987
Several hundred hormones, neurotransmitters, growth factors and other "first messengers" bind to specific cell membrane receptors and induce a myriad of effects: short term, transport, metabolic, mitotic and regulation of thousands of specific genes. Yet, less than a dozen "second messengers" have been clearly established to date. Even allowing for the
D, Lichtstein, D, Rodbard
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Reducing the second messenger

Nature Reviews Microbiology, 2019
This study reports that the intracellular c-di-GMP levels are reduced in Salmonella enterica subsp. enterica serovar Typhimurium during infection of macrophages to promote survival.
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Insulin second messengers

BioEssays, 1997
AbstractThe molecular pathways for insulin's signal transduction from its cell surface receptor to the cell's interior metabolic machinery remain in many ways uncharted. Lately two molecules have been proposed as second messengers transducing the insulin signal into the target cell.
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Second Messengers of Insulin Action

Diabetes Care, 1990
Despite significant advances in past years on the chemistry and biology of insulin and its receptor, the molecular events that couple the insulin-receptor interaction to the regulation of cellular metabolism remain uncertain. Progress in this area has been complicated by the pleiotropic nature of the actions of insulin.
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Intracellular Second Messengers

1997
In the β-cell, the effects of extracellular signals are mediated by changes of concentration of intracellular second messengers. Complex interrelationships among the signalling pathways determine the rate of insulin release and also can modulate the rate of insulin biosynthesis.
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Second Messengers: Sphingolipid signalling

Current Biology, 1994
Sphingomyelin metabolites seem increasingly likely to be intracellular messengers controlling a variety of cell activities, but it is not yet clear exactly which metabolites control which functions, or how they do so.
R H, Michell, M J, Wakelam
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In search of a second messenger for insulin

American Journal of Physiology-Cell Physiology, 1988
Despite significant advances in the past few years on the chemistry and biology of insulin and its receptor, the molecular events that couple the insulin-receptor interaction to the regulation of cellular metabolism remain uncertain. Progress in this area has been complicated by the pleiotropic nature of insulin's actions.
A R, Saltiel, P, Cuatrecasas
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Second messenger signalling in olfaction

Current Opinion in Neurobiology, 1992
The primary reactions of the chemo-electrical signal transduction pathway in olfactory receptor neurons are mediated by two alternative second messengers, cAMP and inositol 1,4,5-trisphosphate. The rapid and transient intracellular signalling is terminated by the action of negative-feedback loops which uncouple the reaction cascades (desensitization ...
H, Breer, I, Boekhoff
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Second Messengers

Perspectives In Psychiatric Care, 2007
Norman L, Keltner, Audry G, Gorman
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