Results 81 to 90 of about 1,865,436 (219)

A Novel Two-Component System PdeK/PdeR Regulates c-di-GMP Turnover and Virulence of Xanthomonas oryzae pv. oryzae

Molecular Plant-Microbe Interactions, 2012
Two-component systems (TCS) consisting of histidine kinases (HK) and response regulators (RR) play essential roles in bacteria to sense environmental signals and regulate cell functions.
Fenghuan Yang, Fang Tian, Lei Sun, Huamin Chen, Maosen Wu, Ching-Hong Yang, Chenyang He   +6 more
doaj   +1 more source

4MOST Consortium Survey 3: Milky Way Disc and Bulge Low-Resolution Survey (4MIDABLE-LR)

, 2019
The mechanisms of the formation and evolution of the Milky Way are encoded in the orbits, chemistry and ages of its stars. With the 4MOST MIlky way Disk And BuLgE Low-Resolution Survey (4MIDABLE-LR) we aim to study kinematic and chemical substructures in
Anders, F., Andrae, R., Arentsen, A., Asplund, M., Bensby, T., Bergemann, M., Casagrande, L., Cescutti, G., Chiappini, C., Church, R., Feltzing, S., Fouesneau, M., Fusillo, N., Gerhard, O., Grebel, E., Guiglion, G., Khalatyan, A., Kordopatis, G., Kovalev, M., Lemasle, B., Matijevic, G., McMillan, P., Minchev, I., Monari, G., Queiroz, A., Rix, H., Rybizki, J., Ryde, N., Schwope, A., Starkenburg, E., Steinmetz, M., Storm, J., Team, 4., Traven, G., Tremblay, P., Valentini, M., Walton, N., Xiang, M., Zucker, D.   +38 more
core   +1 more source

Hidden Messenger from Quantum Geometry: Towards Information Conservation in Quantum Gravity

, 2018
The back reactions of Hawking radiation allow nontrivial correlations between consecutive Hawking quanta, which gives a possible way of resolving the paradox of black hole information loss known as the hidden messenger method. In a recent work of Ma {\it
Cai, Qing-yu, Guo, Xiao-Kan
core   +1 more source

Megasequence architecture of Taranaki, Wanganui, and King Country basins and Neogene progradation of two continental margin wedges across western New Zealand. [PDF]

, 2002
Taranaki, Wanganui and King Country basins (formerly North Wanganui Basin) have been regarded as discrete basins, but they contain a very similar Neogene sedimentary succession and much of their geological history is held in common.
Bland, Kyle J., Griffin, Angela.G., Hayton, Shaun, Hendy, Austin J.W., Kamp, Peter J.J., McIntyre, Avon P., Naish, Timothy R., Nelson, Campbell S., Vonk, Adam J.   +8 more
core   +1 more source

KdpD is a tandem serine histidine kinase that controls K+ pump KdpFABC transcriptionally and post-translationally

Nature Communications
Two-component systems, consisting of a histidine kinase and a response regulator, serve signal transduction in bacteria, often regulating transcription in response to environmental stimuli.
Jakob M. Silberberg, Sophie Ketter, Paul J. N. Böhm, Kristin Jordan, Marcel Wittenberg, Julia Grass, Inga Hänelt   +6 more
doaj   +1 more source

A combination treatment based on drug repurposing demonstrates mutation-agnostic efficacy in pre-clinical retinopathy models

Nature Communications
Inherited retinopathies are devastating diseases that in most cases lack treatment options. Disease-modifying therapies that mitigate pathophysiology regardless of the underlying genetic lesion are desirable due to the diversity of mutations found in ...
Henri Leinonen, Jianye Zhang, Laurence M. Occelli, Umair Seemab, Elliot H. Choi, Luis Felipe L.P. Marinho, Janice Querubin, Alexander V. Kolesnikov, Anna Galinska, Katarzyna Kordecka, Thanh Hoang, Dominik Lewandowski, Timothy T. Lee, Elliott E. Einstein, David E. Einstein, Zhiqian Dong, Philip D. Kiser, Seth Blackshaw, Vladimir J. Kefalov, Marcin Tabaka, Andrzej Foik, Simon M. Petersen-Jones, Krzysztof Palczewski   +22 more
doaj   +1 more source

A genetically encoded biosensor to monitor dynamic changes of c-di-GMP with high temporal resolution

Nature Communications
Monitoring changes of signaling molecules and metabolites with high temporal resolution is key to understanding dynamic biological systems. Here, we use directed evolution to develop a genetically encoded ratiometric biosensor for c-di-GMP, a ubiquitous ...
Andreas Kaczmarczyk, Simon van Vliet, Roman Peter Jakob, Raphael Dias Teixeira, Inga Scheidat, Alberto Reinders, Alexander Klotz, Timm Maier, Urs Jenal   +8 more
doaj   +1 more source

Calcium Binding Proteins] [PDF]

Türk Biyokimya Dergisi, 2006
Calcium ions are essentail for some of the cellular functions, including musclecontraction, adhesion, secretion, motility, growth, differentiation, gene expression,and cell death.
Berivan Tandoğan, N. Nuray Ulusu
doaj  

Sustained sensing as an emerging principle in second messenger signaling systems.

Current Opinion in Microbiology, 2016
M. Orr, Michael Y. Galperin, Vincent T. Lee   +2 more
semanticscholar   +1 more source

Coordination of virulence factors and lifestyle transition in Pseudomonas aeruginosa through single-cell analysis

Communications Biology
Pseudomonas aeruginosa, a versatile Gram-negative opportunistic pathogen, relies on multiple virulence mechanisms, including a Type III Secretion System (T3SS) and several Type VI Secretion Systems (T6SS), to establish infections. The bacterial universal
Haozhe Chen, Gabriele Malengo, Liyun Wang, Olga Vogler, Mandy Renner, Timo Glatter, Nicole Paczia, Daniel Unterweger, Victor Sourjik, Andreas Diepold   +9 more
doaj   +1 more source