Results 121 to 130 of about 60,836 (146)
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Hydroxylation of secondary bile acids in the perfused prairie dog liver
Lipids, 1983AbstractTaurolithocholic acid and deoxycholic acid were perfused into isolated prairie dog livers. Taurolithocholic acid was 7α‐hydroxylated to form taurochenodeoxycholic acid, whereas deoxycholic acid was conjugated and 7α‐hydroxylated to form taurocholic acid.
B I, Cohen +5 more
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Pharmacological Effects of Secondary Bile Acid Microparticles in Diabetic Murine Model
Current Diabetes Reviews, 2022Aim: Examine bile acids effects in Type 2 diabetes. Background: In recent studies, the bile acid ursodeoxycholic acid (UDCA) has shown potent anti-inflammatory effects in obese patients while in type 2 diabetics (T2D) levels of the pro-inflammatory bile acid lithocholic acid were increased, and levels of the anti-inflammatory bile acid ...
Mooranian, Armin +9 more
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Ratio of primary and secondary bile acids in feces
Diseases of the Colon & Rectum, 1999Increases in fecal bile acids may play a role in colorectal carcinogenesis. The authors tested the hypothesis that high concentrations of primary and secondary bile acids are more common in patients with colon cancer than in patients with other gastrointestinal diseases.In this retrospective study the secondary bile acid deoxycholic acid and the ...
T, Kamano +6 more
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Journal of Hepatology, 2001
Lysyl fluorescein conjugated bile acid analogues (LFCBAA) closely parallel their natural counterparts. To assess LFCBAA as a tool for the visualization of bile acid transport within liver tissue.Wistar rats were administered physiological concentrations of the primary bile acid analogue cholyllysyl fluoroscein (CLF) and of the secondary bile acid ...
P, Milkiewicz +6 more
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Lysyl fluorescein conjugated bile acid analogues (LFCBAA) closely parallel their natural counterparts. To assess LFCBAA as a tool for the visualization of bile acid transport within liver tissue.Wistar rats were administered physiological concentrations of the primary bile acid analogue cholyllysyl fluoroscein (CLF) and of the secondary bile acid ...
P, Milkiewicz +6 more
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Analytical Biochemistry, 1978
Abstract An improved method for the isolation and identification of fecal secondary bile acids was developed. This method employs tlc to separate 3α-hydroxycholanoic acids from 3β-hydroxycholanoic acids (iso bile acids). The bile acids were identified by a combination of tlc, glc, and glc/ms. This method was used to analyze fecal material of rats fed
M, Takahashi +4 more
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Abstract An improved method for the isolation and identification of fecal secondary bile acids was developed. This method employs tlc to separate 3α-hydroxycholanoic acids from 3β-hydroxycholanoic acids (iso bile acids). The bile acids were identified by a combination of tlc, glc, and glc/ms. This method was used to analyze fecal material of rats fed
M, Takahashi +4 more
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Downregulation of a human colonic sialyltransferase by a secondary bile acid and a phorbol ester
American Journal of Physiology-Gastrointestinal and Liver Physiology, 1998Fecal constituents such as bile acids and increased sialylation of membrane glycoproteins by α-2,6-sialyltransferase (HST6N-1) may contribute to colorectal tumorigenesis. We hypothesized that bile acids and phorbol ester [12- O-tetradecanoylphorbol-13-acetate (TPA)] would upregulate HST6N-1 in colonic cells.
M, Li +5 more
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S566 Evaluation of Secondary Bile Acids in Stool as Predictors of Chronic Bile Acid (BA) Diarrhea
American Journal of Gastroenterology, 2022Saam Dilmaghani +6 more
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Primary-Secondary-Tertiary Axis of Bile Acid Metabolism in Healthy Subjects
Journal of Proteome ResearchBile acid (BA) metabolism, governed by host-gut microbial interplay, critically regulates the immunometabolic processes. We present the first quantitative framework for human BA dynamics spanning the primary (hepatic synthesis), secondary (microbial metabolism), and tertiary (host modification) metabolic axes.
Bin Cheng +10 more
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Formation of secondary allo-bile acids by novel enzymes from gut Firmicutes
Gut Microbes, 2022João Alves, Tsuyoshi Murai
exaly
The Influence of Total Colectomy on Secondary Bile Acid Metabolism
Biochemical Society Transactions, 1991M C, Winslet +4 more
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