Results 21 to 30 of about 7,825,369 (248)

Serum neurofilament light and MRI predictors of cognitive decline in patients with secondary progressive multiple sclerosis: Analysis from the MS-STAT randomised controlled trial [PDF]

, 2022
Magnetic resonance imaging; Neurofilament light; Secondary progressive multiple sclerosisImatge per ressonància magnètica; Llum del neurofilament; Esclerosi múltiple secundària progressivaImagen por resonancia magnética; Luz de neurofilamento; Esclerosis
Doshi, Anisha, Binks, Sophie, Eshaghi, Arman, Tur Gomez, Carmen, Williams, Thomas, Chan, Dennis   +5 more
core   +1 more source

Risk of secondary progressive multiple sclerosis: A longitudinal study.

, 2020
BACKGROUND: The risk factors for conversion from relapsing-remitting to secondary progressive multiple sclerosis remain highly contested. OBJECTIVE: The aim of this study was to determine the demographic, clinical and paraclinical features that influence
Jun, Jae-Kwan, Spelman, Tim, Pucci, Eugenio, Verheul, Freek, Fragoso, Yara, Yamout, Bassem, Al-Harbi, Talal, Bergamaschi, Roberto, Gray, Orla, Butzkueven, Helmut, Prat, Alexandre, Turkoglu, Recai, McCombe, Pamela, Grand'Maison, Francois, Lugaresi, Alessandra, Alroughani, Raed, Terzi, Murat, Petersen, Thor, Slee, Mark, Shaw, Cameron, Hughes, Jordana, Barnett, Michael, Moore, Fraser, Trojano, Maria, Vucic, Steve, Olascoaga, Javier, Horakova, Dana, Saladino, Maria Laura, Altintas, Ayse, Sanchez-Menoyo, Jose Luis, Deri, Norma, Kubala Havrdova, Eva, Skibina, Olga, Ozakbas, Serkan, Iuliano, Gerardo, Cristiano, Edgardo, Taylor, Bruce, Ferraro, Diana, Fambiatos, Adam, Izquierdo, Guillermo, Van Pesch, Vincent, Ampapa, Radek, Van Wijmeersch, Bart, Lechner-Scott, Jeannette, Granella, Franco, Sidhom, Youssef, Boz, Cavit, Hupperts, Raymond, Spitaleri, Daniele, Girard, Marc, Solaro, Claudio, Duquette, Pierre, Soysal, Aysun, Singhal, Bhim, Shuey, Neil, Hodgkinson, Suzanne, Csepany, Tunde, Havrdova, Eva Kubala, Jokubaitis, Vilija, Prevost, Julie, Grammond, Pierre, Kalincik, Tomas, Sola, Patrizia, van der Walt, Anneke   +63 more
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Clinical markers for unfavorable course of multiple sclerosis [PDF]

Анналы клинической и экспериментальной неврологии, 2023
Objective. To study possible clinical markers associated with the unfavorable course of multiple sclerosis and its transition to a progressive subtype. Materials and methods.
Mariya S. Matrosova, Galina N. Belskaya, Vasiliy V. Bryukhov, Ekaterina V. Popova, Marina V. Krotenkova   +4 more
doaj   +1 more source

Setting a research agenda for progressive multiple sclerosis: The International Collaborative on Progressive MS [PDF]

, 2012
Despite significant progress in the development of therapies for relapsing MS, progressive MS remains comparatively disappointing. Our objective, in this paper, is to review the current challenges in developing therapies for progressive MS and identify ...
Salvetti, M, D. Brown, T. Coetzee, K. Sharrock, Lee, K, Brown, D, Feinstein, A, Thompson, A, K. Zuidwijk, D. Chandraratna, Kapoor, R, Fox, RJ, Zuidwijk, K, K. Lee, A. Thompson, G. Comi, Toosy, A, Baneke, P, Browne, P, Sharrock, K, O. Ciccarelli, P. Browne, A. Feinstein, Comi, G, R. J. Fox, Chandraratna, D, P. Zaratin, Baker, D, R. Kapoor, Ciccarelli, O, Zaratin, P, P. Baneke, Coetzee, T, D. Baker, SALVETTI, Marco, A. Toosy   +35 more
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Cerebrospinal fluid ATP metabolites in multiple sclerosis [PDF]

, 2010
Increased axonal energy demand and mitochondrial failure have been suggested as possible causes for axonal degeneration and disability in multiple sclerosis.Our objective was to test whether ATP depletion precedes clinical, imaging and biomarker evidence
Uitdehaag, BMJ, Di Pietro, V., Barkhof, F., Killestein, J, Belli, A.; id_orcid, Killestein, J., Uitdehaag, B.M.J., Eikelenboom, M.J., University of Catania, Tavazzi, B, Petzold, A.F.S., Petzold, A., Petzold, A, Belli, A., Eikelenboom, MJ, Lazzarino, G., Lazzarino, G, Di Pietro, V, Polman, CH, Amorini, A.M., Barkhof, F, Tavazzi, B., Polman, C.H., Belli, A, Di Pietro, V.; id_orcid, Amorini, AM, Pietro, V. Di   +26 more
core   +1 more source

Serum S100B in primary progressive multiple sclerosis patients treated with interferon-beta-1a. [PDF]

, 2004
S100B belongs to a family of calcium-binding proteins implicated in intracellular and extracellular regulatory activities. This study of serum S100B in primary progressive multiple sclerosis (PPMS) is based on data obtained from a randomized, controlled ...
Lim, Ee Tuan, Leary, Siobhan M, Geoff Keir, Petzold, Axel, Thompson, Alan J, Gavin Giovannoni, Siobhan M Leary, Altmann, Daniel R, Keir, Geoff, Ee Tuan Lim, David H Miller, Ed J Thompson, Giovannoni, Gavin, Miller, David H, Alan J Thompson, Daniel R Altmann, Thompson, Ed J, Axel Petzold   +17 more
core   +2 more sources

Secondary Progression is Not the Only Explanation

Acta Médica Portuguesa, 2014
Multiple sclerosis is an inflammatory demyelinating disorder of the central nervous system. Its presentation is variable and its course and prognosis are unpredictable.
Filipe Palavra, Carmen Tur, Mar Tintoré, Àlex Rovira, Xavier Montalban   +4 more
doaj   +1 more source

Delayed P100-Like Latencies in Multiple Sclerosis: A Preliminary Investigation Using Visual Evoked Spread Spectrum Analysis. [PDF]

PLoS ONE, 2016
Conduction along the optic nerve is often slowed in multiple sclerosis (MS). This is typically assessed by measuring the latency of the P100 component of the Visual Evoked Potential (VEP) using electroencephalography.
Hanni S M Kiiski, Sinéad Ní Riada, Edmund C Lalor, Nuno R Gonçalves, Hugh Nolan, Robert Whelan, Róisín Lonergan, Siobhán Kelly, Marie Claire O'Brien, Katie Kinsella, Jessica Bramham, Teresa Burke, Seán Ó Donnchadha, Michael Hutchinson, Niall Tubridy, Richard B Reilly   +15 more
doaj   +1 more source

Changes in retinal structures as markers of multiple sclerosis progression

Неврология, нейропсихиатрия, психосоматика, 2021
The involvement of the visual pathway in multiple sclerosis (MS) pathology determines the importance of studying the structures of the retina for earlier diagnosis and monitoring the severity of the neurodegeneration.
M. O. Poplyak, A. G. Trufanov, A. V. Temniy, D. S. Maltsev, O. B. Chakchir, A. V. Mikheev, D. I. Skulyabin, G. N. Bisaga, I. V. Litvinenko, M. M. Odinak   +9 more
doaj   +1 more source

T2 lesion location really matters: a 10 year follow-up study in primary progressive multiple sclerosis [PDF]

, 2010
Objectives: Prediction of long term clinical outcome in patients with primary progressive multiple sclerosis (PPMS) using imaging has important clinical implications, but remains challenging.
Polman, C., Barkhof, F., Montalban, X, CHARD D, Thompson, A, Polman, C, F. Barkhof, Chard, D, Samson, R., D. Miller, Bodini, B., A. Thompson, Samson, R, MONTALBAN X, R. Samson, Rovira, A, POLMAN C, KHALEELI Z, O. Ciccarelli, Filippi, M., N. De Stefano, Barkhof, F, BATTAGLINI, MARCO, B. Bodini, A. Rovira, Battaglini, M, Polman, C.H., Chard, D., CICCARELLI O., Miller, D., Rovaris, M, Battaglini, M., Thompson, A., De Stefano, N., X. Montalban, MILLER D, ROVARIS M, FILIPPI M, D. Chard, Khaleeli, Z, SAMSON R, ROVIRA A, THOMPSON A, Rovaris, M., De Stefano, N, Rovira, A., Z. Khaleeli, Bodini, B, BODINI B, M. Filippi, Miller, D, BARKHOF F, DE STEFANO, NICOLA, M. Rovaris, Montalban, X., Ciccarelli, O., Ciccarelli, O, Khaleeli, Z., M. Battaglini, C. Polman, Filippi, M, Rovira, Alex, Stefano, N. De, Rovaris, Marco, Thompson, Alan, De Stefano N, Battaglini M, FILIPPI , MASSIMO, Barkhof, Frederik, Polman, Chris, Montalban, Xavier, Ciccarelli, Olga, Miller, David, Filippi, Massimo, Khaleeli, Zhaleh, Chard, Declan, Filippi, M., Bodini, Benedetta, Samson, Rebecca   +78 more
core   +1 more source