Results 11 to 20 of about 11,591,695 (294)

Protein secondary structure prediction

Current Opinion in Structural Biology, 1995
The past year has seen a consolidation of protein secondary structure prediction methods. The advantages of prediction from an aligned family of proteins have been highlighted by several accurate predictions made 'blind', before any X-ray or NMR structure was known for the family.
S R, Krystek, W J, Metzler, J, Novotny
core   +6 more sources

Improving the accuracy of protein secondary structure prediction using structural alignment [PDF]

BMC Bioinformatics, 2006
Background The accuracy of protein secondary structure prediction has steadily improved over the past 30 years. Now many secondary structure prediction methods routinely achieve an accuracy (Q3) of about 75%.
Gallin Warren J, Sundararaj Shan, Montgomerie Scott, Wishart David S   +3 more
doaj   +2 more sources

Secondary structure prediction for modelling by homology

"Protein Engineering, Design and Selection", 1993
An improved method of secondary structure prediction has been developed to aid the modelling of proteins by homology. Selected data from four published algorithms are scaled and combined as a weighted mean to produce consensus algorithms. Each consensus algorithm is used to predict the secondary structure of a protein homologous to the target protein ...
Boscott, P. E., Barton, G. J., Richards, W. G.   +2 more
openaire   +4 more sources

Prediction of protein secondary structure based on an improved channel attention and multiscale convolution module

Frontiers in Bioengineering and Biotechnology, 2022
Prediction of the protein secondary structure is a key issue in protein science. Protein secondary structure prediction (PSSP) aims to construct a function that can map the amino acid sequence into the secondary structure so that the protein secondary ...
Xin Jin, Xin Jin, Lin Guo, Lin Guo, Qian Jiang, Qian Jiang, Nan Wu, Nan Wu, Shaowen Yao, Shaowen Yao   +9 more
doaj   +1 more source

PS4: a next-generation dataset for protein single-sequence secondary structure prediction

BioTechniques, 2023
Protein secondary structure prediction is a subproblem of protein folding. A light-weight algorithm capable of accurately predicting secondary structure from only the protein residue sequence could provide useful input for tertiary structure prediction ...
Omar Peracha
doaj   +1 more source

Statistical Evidence for a Helical Nascent Chain

Biomolecules, 2021
We investigate the hypothesis that protein folding is a kinetic, non-equilibrium process, in which the structure of the nascent chain is crucial. We compare actual amino acid frequencies in loops, α-helices and β-sheets with the frequencies that would ...
Leonor Cruzeiro, Andrew C. Gill, J. Chris Eilbeck   +2 more
doaj   +1 more source

RNA Secondary Structure Prediction [PDF]

Current Protocols in Nucleic Acid Chemistry, 2000
AbstractDetails for predicting secondary structure of RNA sequences using free energy minimization are given. Protocols present the use of the RNAstructure computer program (for PCs) and the mfold server (for Unix platforms). The minimum free energy structure and a set of suboptimal structures with similar free energies are predicted.
Mathews, David H., Turner, Douglas H., Zuker, Michael   +2 more
openaire   +5 more sources

The predicted secondary structure of enolase [PDF]

Biochemical Journal, 1986
The results of several secondary-structure prediction programs were combined to produce an estimate of the regions of alpha-helix, beta-sheet and reverse turn for both chicken skeletal-muscle and yeast enolase sequences. The predicted secondary-structure content of the chicken enzyme is 27% alpha-helix and less than 10% beta-sheet, whereas in the yeast
L, Sawyer, L A, Fothergill-Gilmore, G A, Russell   +2 more
openaire   +2 more sources

ATTfold: RNA Secondary Structure Prediction With Pseudoknots Based on Attention Mechanism

Frontiers in Genetics, 2020
Accurate RNA secondary structure information is the cornerstone of gene function research and RNA tertiary structure prediction. However, most traditional RNA secondary structure prediction algorithms are based on the dynamic programming (DP) algorithm ...
Yili Wang, Yili Wang, Yuanning Liu, Yuanning Liu, Shuo Wang, Shuo Wang, Zhen Liu, Zhen Liu, Zhen Liu, Yubing Gao, Yubing Gao, Hao Zhang, Hao Zhang, Liyan Dong, Liyan Dong   +14 more
doaj   +1 more source

The Future of Protein Secondary Structure Prediction Was Invented by Oleg Ptitsyn

Biomolecules, 2020
When Oleg Ptitsyn and his group published the first secondary structure prediction for a protein sequence, they started a research field that is still active today.
Daniel Rademaker, Jarek van Dijk, Willem Titulaer, Joanna Lange, Gert Vriend, Li Xue   +5 more
doaj   +1 more source