Results 71 to 80 of about 34,649 (253)

Secretin [PDF]

open access: yesProceedings of the Royal Society of London. Series B, Containing Papers of a Biological Character, 1932
The preparation of secretin has been described in a previous paper (1928). The method involved extraction of the duodenal mucosa with absolute alcohol and precipitation of the dissolved secretin by bile salts. It was based on two observations: ( a ) secretin exists in the duodenal mucosa in an active condition, and (
openaire   +1 more source

A Review on the Cognitive Neuroscience of Autism [PDF]

open access: yes, 2005
With increased recognition in the media, heightened prevalence, and advances in research technologies, investigation into the causes of autism has broadened in recent years.
Koyama, Alain
core  

On the hierarchical classification of G Protein-Coupled Receptors [PDF]

open access: yes, 2007
Motivation: G protein-coupled receptors (GPCRs) play an important role in many physiological systems by transducing an extracellular signal into an intracellular response. Over 50% of all marketed drugs are targeted towards a GPCR.
A. A. Freitas   +31 more
core   +2 more sources

The role of dimerisation in the cellular trafficking of G-protein-coupled receptors [PDF]

open access: yes, 2010
The concept that G-protein-coupled receptors can exist as homomeric and/or heteromeric complexes is now well established. Despite this, how dynamic such interactions are and if this may be modulated during receptor trafficking remain topics of debate ...
Milligan, Graeme
core   +1 more source

Piezo2 in Mechanosensory Biology: From Physiological Homeostasis to Disease‐Promoting Mechanisms

open access: yesCell Proliferation, Volume 59, Issue 1, January 2026.
Piezo2 channels are essential mechanotransducers regulating touch, proprioception and visceral mechanosensation across physiological systems, emerging as therapeutic targets for pathological mechanical hypersensitivity and neurogenic disorders. ABSTRACT Piezo2, a mechanically activated ion channel, serves as the key molecular transducer for touch ...
Zhebin Cheng   +4 more
wiley   +1 more source

Diagnostic Accuracy of a Short Endoscopic Secretin Test in Patients With Cystic Fibrosis

open access: yesPancreas, 2015
Objective Short endoscopic secretin tests for exocrine pancreatic function are not properly evaluated in cystic fibrosis (CF). Methods Patients with CF and healthy controls (HCs) underwent endoscopic collection of duodenal juice between 30 and 45 minutes
Trond Engjom   +6 more
semanticscholar   +1 more source

Cardiac fibrosis induced by high‐fat diet in ApoE‐deficient male mice is exacerbated by genetic deletion of PACAP–PAC1 signaling

open access: yesJournal of Neuroendocrinology, Volume 38, Issue 1, January 2026.
Abstract Cardiac fibrosis is characterized by an excessive accumulation of extracellular matrix proteins and occurs in a variety of cardiac diseases, such as the highly prevalent syndrome heart failure with preserved ejection fraction (HFpEF) and other cardiac disorders.
J. M. Schubart   +11 more
wiley   +1 more source

Corticotropin-Releasing Factor: An Ancient Peptide Family Related to the Secretin Peptide Superfamily

open access: yesFrontiers in Endocrinology, 2020
Corticotropin-releasing factor (CRF) is the hypothalamic releasing peptide that regulates the hypothalamic-pituitary-adrenal/inter-renal (HPA/I) axis in vertebrates.
Ola M. Michalec   +3 more
doaj   +1 more source

The Role of Pepsinogenes and Some Intestinal Hormones in Pathogenesis of Gastroesophageal Reflux Disease [PDF]

open access: yes, 2018
80 patients with gastroesophageal reflux disease (GERD) were examined. The diagnosis of GERD was based on the history of the disease, complaints of patients, the results of daily monitoring of pH in the lower third of the esophagus, data of ...
Boichuk, V. (Vira)
core   +2 more sources

Medical Management of Polycystic Liver Disease: A Position Statement From the European Reference Network on Hepatological Diseases

open access: yesLiver International, Volume 46, Issue 1, January 2026.
ABSTRACT Polycystic liver disease (PLD) is a rare genetic disorder characterised by progressive liver enlargement due to multiple cysts. The main symptoms are liver volume‐related. Although randomised controlled trials have shown that somatostatin analogues (SSAs) reduce liver volume as well as symptoms, specific guidance on when and how to use SSAs in
Sophia Heinrich   +16 more
wiley   +1 more source

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