Results 81 to 90 of about 15,697 (209)

Etiology and pathogenesis of duodenal mucosa lesion in chronic pancreatitis

Терапевтический архив, 2009
Aim. To measure content of neuromediators (acetylcholine - Ach, serotonin - 5-NT) and gastrointestinal hormones (cholecystokinine - CCK and secretin) in the blood serum of patients with chronic pancreatitis (CP); to study protective properties of the ...
Lyudmila Vasil'evna Vinokupova, V N Dpozdov, E V Tkachenko, I E Tpubitsyna, G G Vapvanina, L V Vinokurova, V N Drozdov, E V Tkachenko, I E Trubitsyna, G G Varvanina   +9 more
doaj  

Structure of a type IV pilus machinery in the open and closed state

eLife, 2015
Proteins of the secretin family form large macromolecular complexes, which assemble in the outer membrane of Gram-negative bacteria. Secretins are major components of type II and III secretion systems and are linked to extrusion of type IV pili (T4P) and
Vicki AM Gold, Ralf Salzer, Beate Averhoff, Werner Kühlbrandt   +3 more
doaj   +1 more source

Secretin receptors in the human liver: expression in biliary tract and cholangiocarcinoma, but not in hepatocytes or hepatocellular carcinoma

, 2006
BACKGROUND/AIMS: Gut hormone receptors are over-expressed in human cancer and allow receptor-targeted tumor imaging and therapy. A novel promising receptor for these purposes is the secretin receptor.
Hayes, Gregory M, Reubi, Jean Claude, Miller, Laurence J, Wiedenmann, Bertram, Scholz, Arne, Rehmann, Ruth, Zimmermann, Arthur, Körner, Meike   +7 more
core   +1 more source

An immunohistochemical study of endocrine cells in the pancreas of the Red-bellied frog (Bombina orientalis)

European Journal of Histochemistry, 2009
The regional distribution and frequency of pancreatic endocrine cells in the red-bellied frog, Bombina orientalis, were studied by the immunohistochemical peroxidase antiperoxidase (PAP) method using five types of specific mammalian antisera to insulin ...
JH Lee, SK Ku, HS Lee, H Kitagawa
doaj   +1 more source

Outer Membrane Targeting of Secretin PulD Protein Relies on Disordered Domain Recognition by a Dedicated Chaperone

, 2011
International audienceInteraction of bacterial outer membrane secretin PulD with its dedicated lipoprotein chaperone PulS relies on a disorder-to-order transition of the chaperone binding (S) domain near the PulD C terminus.
Tommaso Tosi, Patrick England, Andréa Dessen, Nickerson, Nicholas, N., Pugsley, Anthony, Nicholas N. Nickerson, Bruno Baron, Tosi, Tommaso, Bertrand Raynal, Raynal, Bertrand, Dessen, Andréa, Baron, Bruno, Anthony P. Pugsley, England, Patrick   +13 more
core   +1 more source

Role of the secretin/secretin receptor axis in the modulation of the liver fibrosis [PDF]

, 2017
Proliferating cholangiocytes, the cells that line the biliary ducts, secrete and respond to neuroendocrine hormones, including secretin. Secretin stimulates biliary proliferation by downregulation of let-7a and subsequent upregulation of the growth ...
Mancinelli, Romina, Alpini, Gianfranco, Gaudio, Eugenio, Glaser, Shannon   +3 more
core   +1 more source

Synthetic Peptides as Therapeutic Agents: Lessons Learned From Evolutionary Ancient Peptides and Their Transit Across Blood-Brain Barriers

Frontiers in Endocrinology, 2019
Peptides play a major role in the transmission of information to and from the central nervous system. However, because of their structural complexity, the development of pharmacological peptide-based therapeutics has been challenged by the lack of ...
David A. Lovejoy, David A. Lovejoy, David W. Hogg, Thomas L. Dodsworth, Fernando R. Jurado, Casey C. Read, Andrea L. D'Aquila, Andrea L. D'Aquila, Dalia Barsyte-Lovejoy   +8 more
doaj   +1 more source

Secretin receptors mediating rat forestomach relaxation

, 1993
Frozen sections of the rat stomach were incubated with 125I-labeled porcine secretin, and then secretin binding sites were localized by autoradiography.
S. R. Vigna, D. C. McVey, A. W. Mangel, T. S. Steiner   +3 more
core   +1 more source

On Secretin Radioimmunoassay and its Clinical Application [PDF]

, 1978
Radioimmunoassay （RIA） for the determination of plasma secretin was investigated fundamentally and was clinically applied for the examination of secretin release in response to an intraduodenal acid infusion.
稲辺, 靖仁郎, 大原, 弘通
core   +1 more source

ANCOVA Analysis of Secretin-Dependent Signals in the Ventromedial Hypothalamus Regulate Energy Metabolism and Bone Homeostasis in Mice

<p>Full R pipeline for ancova analysis in Journal article: Secretin-Dependent Signals in the Ventromedial Hypothalamus Regulate Energy Metabolism and Bone Homeostasis in Mice.
Congjia Chen
core   +1 more source