Results 71 to 80 of about 15,697 (209)
mBio, 2017 The type II secretion system (T2SS) releases large folded exoproteins across the envelope of many Gram-negative pathogens. This secretion process therefore requires specific gating, interacting, and dynamics properties mainly operated by a bipartite ...
Badreddine Douzi +11 more
doaj +1 more source
, 1983 We prepared 125I-secretin and studied the kinetics, stoichiometry, and chemical specificity with which the labeled peptide binds to dispersed acini prepared from guinea pig pancreas.
T. L. O'Donohue +5 more
core +1 more source
Hypothalamic Control of Liver Health and Disease: From Circuits to Pathophysiology and Therapies
Advanced Science, Volume 13, Issue 47, 24 August 2026.This review delineates the hypothalamic circuits that control liver homeostasis via autonomic and neuroendocrine pathways. Dysregulation of this hypothalamus–liver axis drives disease progression across a spectrum including steatotic liver disease, liver inflammation and injury, fibrosis, cirrhosis, and hepatocellular carcinoma.
Qin Tang +7 more
wiley +1 more source
, 2008 Gastrointestinal peptide hormone receptors, like somatostatin receptors, are often overexpressed in human cancer, allowing receptor-targeted tumor imaging and therapy.
Hayes, Gregory M +5 more
core +1 more source
Proceedings of the Royal Society of London. Series B, Containing Papers of a Biological Character, 1932 Abstract The preparation of secretin has been described in a previous paper (1928). The method involved extraction of the duodenal mucosa with absolute alcohol and precipitation of the dissolved secretin by bile salts. It was based on two observations: (a) secretin exists in the duodenal mucosa in an active condition, and (b) the ...
openaire +1 more source
Gastrinoma de localização pilórica numa doente com úlcera péptica recorrente.
Acta Médica Portuguesa, 1992 We report a clinical case of a woman, 56 years old, with a history of duodenal ulcer and esophagitis, under medication with H2 receptors blockers during 3 years. Plasma basal gastrin was near normal levels. A stimulation test with secretin was compatible
P Duarte +4 more
doaj +1 more source
Imaging of the Liver and Pancreas: The Added Value of MRI
DiagnosticsMR is a powerful diagnostic tool in the diagnosis and management of most hepatic and pancreatic diseases. Thanks to its multiple sequences, the use of dedicated contrast media and special techniques, it allows a multiparametric approach able to provide ...
Giovanni Morana +4 more
doaj +1 more source
Elucidation of secretin-pilotin interactions.
, 2012 Titration of secretin peptides into 15N labelled pilotin. 1H-15N-HSQC spectra of the pilotin in the absence of secretin (red spectra), in the presence of 62 residue secretin peptide (green) and in the presence of 18 residue peptide (black).
Shuang Gu (184317) +4 more
core +1 more source
PLoS Pathogens, 2019 The type II secretion system (T2SS) is a cell envelope-spanning macromolecular complex that is prevalent in Gram-negative bacterial species. It serves as the predominant virulence mechanism of many bacteria including those of the emerging human pathogens
S Peter Howard +9 more
doaj +1 more source
PLoS Pathogens, 2013 The Type II Secretion System (T2SS) is a molecular machine that drives the secretion of fully-folded protein substrates across the bacterial outer membrane.
Rhys A Dunstan +10 more
doaj +1 more source