Results 61 to 70 of about 15,697 (209)

Prospective comparison of secretin-stimulated magnetic resonance cholangiopancreatography with manometry in the diagnosis of sphincter of Oddi dysfunction types II and III [PDF]

, 2007
Background: In sphincter of Oddi dysfunction (SOD), sphincter of Oddi manometry (SOM) predicts the response to sphincterotomy, but is invasive and associated with complications.
Pereira, S.P., Hatfield, A.R.W., Gillams, A., Webster, G.J.M., Sgouros, S.N.   +4 more
core  

Extragastrointestinal functions and transcriptional regulation of secretin and secretin receptors

, 2011
The functional role of secretin outside the gastrointestinal system has been a mystery to endocrinologists for many years. With the availability of secretin- and secretin receptor-knockout models and the advances of electrophysiological and ...
Lee, LTO, Ng, SS, Yuan, Y, Chow, BKC
core   +1 more source

Impact of secretin receptor homo-dimerization on natural ligand binding

Nature Communications
Class B G protein-coupled receptors can form dimeric complexes important for high potency biological effects. Here, we apply pharmacological, biochemical, and biophysical techniques to cells and membranes expressing the prototypic secretin receptor (SecR)
Kaleeckal G. Harikumar, Sarah J. Piper, Arthur Christopoulos, Denise Wootten, Patrick M. Sexton, Laurence J. Miller   +5 more
doaj   +1 more source

Recurrent acute pancreatitis caused by a duodenal diverticulum: The diagnostic value of secretin‐enhanced magnetic resonance cholangiopancreatography

Journal of Pediatric Gastroenterology and Nutrition, EarlyView.
Dagmar H. Zeef, Roy S. Dwarkasing, Annick S. Devos, Wim J. Lammers, Conny J. H. M. Meeussen, Marjolein van Waas   +5 more
wiley   +1 more source

The Role and Mechanism of Incretins in Gynaecologic Diseases

Endocrinology, Diabetes &Metabolism, Volume 9, Issue 5, September 2026.
This review outlines the mechanisms of incretins in polycystic ovary syndrome, endometriosis and gynaecological cancers, highlighting the translational potential of incretin‐based therapies for metabolic‐associated gynaecological disorders. ABSTRACT Background Obesity is a major global public health concern closely linked to the development and ...
Jiayu Yan, Minyue Cao, Yan Ding, Yiqin Zhang, Yihan Sun, Genyi Jiang, Yanli Zhang, Luyao Kang, Xue Zhou, Jing Luo, Bilan Li   +10 more
wiley   +1 more source

Modulation of secretin release by neuropeptides in secretin-producing cells

, 1998
Nerve fibers containing bombesin (BB)/gastrin-releasing polypeptide (GRP), pituitary adenylate cyclase-activating polypeptide (PACAP), vasoactive intestinal polypeptide (VIP), or galanin are known to innervate the mucosa of the upper small intestine ...
William Y. Chey, Brian Erway, Ta-Min Chang, David H. Coy, Cecilia H. Chang   +4 more
core   +1 more source

Exocrine Gland Dysfunction in Parkinson's Disease: Pathophysiology, Clinical Manifestations, and Therapeutic Perspectives—A Narrative Review

Movement Disorders Clinical Practice, Volume 13, Issue 9, Page 2081-2092, September 2026.
Abstract Background Non‐motor symptoms, especially autonomic dysfunction, are major contributors to disability and decreased quality of life in Parkinson's disease (PD). Despite being common and having a wide range of clinical facets, exocrine gland dysfunction is still not well recognized and managed.
Renato P. Munhoz, Marina Farah, Laura Silveira‐Moriyama   +2 more
wiley   +1 more source

The role of opioid peptides in the regulation of secretin-stimulated bile secretion

Бюллетень сибирской медицины, 2006
Influence of intraperitoneal dalargin (dand m-opioid agonist), DADLE (d-opioid agonist), DAGO (m-opioid agonist) and U50488 (k-opioid agonist) on bile secretion which is stimulated by secretin was studied in sharp experiments on white rats.
M. A. Medvedev, I. V. Roudin
doaj   +1 more source

Glucagon‐Like Peptide‐1 Receptor Agonist‐Based Agents and Body Composition: Filling More Gaps

Obesity, Volume 34, Issue S2, Page 51-63, September 2026.
ABSTRACT The last 2 decades have seen historic advances in the treatment of obesity. We are entering an era of defining obesity not by weight‐based outcomes but by changes in body composition. Glucagon‐like peptide‐1 receptor agonists (GLP‐1 RAs) are forming the platform for obesity treatments based on their high level of efficacy. Body composition can
Robert L. Dubin, Tierra N. Sanders, Hunter M. Schwab, Steven B. Heymsfield, Frank L. Greenway   +4 more
wiley   +1 more source

Current Cell/Organoid and Animal Models for Primary Sclerosing Cholangitis

Portal Hypertension &Cirrhosis, Volume 5, Issue 3, Page 241-259, September 2026.
Primary sclerosing cholangitis (PSC) is a chronic cholestatic liver disease with limited therapeutic options and a marked risk of progression to biliary fibrosis, cirrhosis, and malignancy. Progress in PSC research has been hindered by the lack of models that faithfully recapitulate the complex biliary microenvironment and disease heterogeneity ...
Qigu Yao, Sheng Cheng, Qiaoling Pan, Jiong Yu, Hongcui Cao   +4 more
wiley   +1 more source