Results 61 to 70 of about 11,220 (181)

Gastrinoma de localização pilórica numa doente com úlcera péptica recorrente.

Acta Médica Portuguesa, 1992
We report a clinical case of a woman, 56 years old, with a history of duodenal ulcer and esophagitis, under medication with H2 receptors blockers during 3 years. Plasma basal gastrin was near normal levels. A stimulation test with secretin was compatible
P Duarte, Z Luz, I Lourenço, B Reis, A Alvelos   +4 more
doaj   +1 more source

Etiology and pathogenesis of duodenal mucosa lesion in chronic pancreatitis

Терапевтический архив, 2009
Aim. To measure content of neuromediators (acetylcholine - Ach, serotonin - 5-NT) and gastrointestinal hormones (cholecystokinine - CCK and secretin) in the blood serum of patients with chronic pancreatitis (CP); to study protective properties of the ...
Lyudmila Vasil'evna Vinokupova, V N Dpozdov, E V Tkachenko, I E Tpubitsyna, G G Vapvanina, L V Vinokurova, V N Drozdov, E V Tkachenko, I E Trubitsyna, G G Varvanina   +9 more
doaj  

Imaging of the Liver and Pancreas: The Added Value of MRI

Diagnostics
MR is a powerful diagnostic tool in the diagnosis and management of most hepatic and pancreatic diseases. Thanks to its multiple sequences, the use of dedicated contrast media and special techniques, it allows a multiparametric approach able to provide ...
Giovanni Morana, Alessandro Beleù, Luca Geraci, Luisa Tomaiuolo, Silvia Venturini   +4 more
doaj   +1 more source

Structure and assembly of pilotin-dependent and -independent secretins of the type II secretion system.

PLoS Pathogens, 2019
The type II secretion system (T2SS) is a cell envelope-spanning macromolecular complex that is prevalent in Gram-negative bacterial species. It serves as the predominant virulence mechanism of many bacteria including those of the emerging human pathogens
S Peter Howard, Leandro F Estrozi, Quentin Bertrand, Carlos Contreras-Martel, Timothy Strozen, Viviana Job, Alexandre Martins, Daphna Fenel, Guy Schoehn, Andréa Dessen   +9 more
doaj   +1 more source

Assembly of the type II secretion system such as found in Vibrio cholerae depends on the novel Pilotin AspS.

PLoS Pathogens, 2013
The Type II Secretion System (T2SS) is a molecular machine that drives the secretion of fully-folded protein substrates across the bacterial outer membrane.
Rhys A Dunstan, Eva Heinz, Lakshmi C Wijeyewickrema, Robert N Pike, Anthony W Purcell, Timothy J Evans, Judyta Praszkier, Roy M Robins-Browne, Richard A Strugnell, Konstantin V Korotkov, Trevor Lithgow   +10 more
doaj   +1 more source

Structure of a type IV pilus machinery in the open and closed state

eLife, 2015
Proteins of the secretin family form large macromolecular complexes, which assemble in the outer membrane of Gram-negative bacteria. Secretins are major components of type II and III secretion systems and are linked to extrusion of type IV pili (T4P) and
Vicki AM Gold, Ralf Salzer, Beate Averhoff, Werner Kühlbrandt   +3 more
doaj   +1 more source

Secretin-interacting plug proteins prevent antibiotic influx during type IV pilus assembly in Pseudomonas aeruginosa

Nature Communications
Type IV pili (T4P) are important virulence factors that mediate host attachment and other pathogenic functions. In Gram-negative bacteria, T4P are assembled from pilin subunits at the inner membrane (IM) and extend through the outer membrane (OM) via ...
Oh Hyun Kwon, Yeseul Lee, Bumhan Ryu, Joel W. Sher, Sohee Park, Frédéric Lauber, Bi-o Kim, Youngki Yoo, Seung-Hyun Cho, Donghui Choe, You-Hee Cho, Jean-François Collet, Melanie D. Ohi, Thomas G. Bernhardt, Jeong Min Chung, Hongbaek Cho   +15 more
doaj   +1 more source

An immunohistochemical study of endocrine cells in the pancreas of the Red-bellied frog (Bombina orientalis)

European Journal of Histochemistry, 2009
The regional distribution and frequency of pancreatic endocrine cells in the red-bellied frog, Bombina orientalis, were studied by the immunohistochemical peroxidase antiperoxidase (PAP) method using five types of specific mammalian antisera to insulin ...
JH Lee, SK Ku, HS Lee, H Kitagawa
doaj   +1 more source

Synthetic Peptides as Therapeutic Agents: Lessons Learned From Evolutionary Ancient Peptides and Their Transit Across Blood-Brain Barriers

Frontiers in Endocrinology, 2019
Peptides play a major role in the transmission of information to and from the central nervous system. However, because of their structural complexity, the development of pharmacological peptide-based therapeutics has been challenged by the lack of ...
David A. Lovejoy, David A. Lovejoy, David W. Hogg, Thomas L. Dodsworth, Fernando R. Jurado, Casey C. Read, Andrea L. D'Aquila, Andrea L. D'Aquila, Dalia Barsyte-Lovejoy   +8 more
doaj   +1 more source

Structural and functional insights into the pilotin-secretin complex of the type II secretion system.

PLoS Pathogens, 2012
Gram-negative bacteria secrete virulence factors and assemble fibre structures on their cell surface using specialized secretion systems. Three of these, T2SS, T3SS and T4PS, are characterized by large outer membrane channels formed by proteins called ...
Shuang Gu, Saima Rehman, Xiaohui Wang, Vladimir E Shevchik, Richard W Pickersgill   +4 more
doaj   +1 more source