Results 1 to 10 of about 2,579,679 (405)

Blood concentrations of small extracellular vesicles are determined by a balance between abundant secretion and rapid clearance

Journal of Extracellular Vesicles, 2020
Small extracellular vesicles (sEVs) are important mediators of cell–cell communication with respect to diverse physiological processes. To further understand their physiological roles, understanding blood sEV homoeostasis in a quantitative manner is ...
Yuki Takahashi, Yasushi Ishihama
exaly   +2 more sources

Metformin Improves Autonomic Nervous System Imbalance and Metabolic Dysfunction in Monosodium L-Glutamate-Treated Rats

Frontiers in Endocrinology, 2021
Metformin is an antidiabetic drug used for the treatment of diabetes and metabolic diseases. Imbalance in the autonomic nervous system (ANS) is associated with metabolic diseases.
Claudinéia Conationi da Silva Franco, Carina Previate, Amanda Bianchi Trombini, Rosiane Aparecida Miranda, Luiz Felipe Barella, Lucas Paulo Jacinto Saavedra, Júlio Cezar de Oliveira, Kelly Valério Prates, Laize Peron Tófolo, Tatiane Aparecida Ribeiro, Audrei Pavanello, Ananda Malta, Isabela Peixoto Martins, Veridiana Motta Moreira, Camila Cristina Ianoni Matiusso, Flávio Andrade Francisco, Vander Silva Alves, Ana Maria Praxedes de Moraes, Juliane Rocha de Sant Anna, Marialba Avezum Alves de Castro Prado, Rodrigo Mello Gomes, Elaine Vieira, Paulo Cezar de Freitas Mathias   +22 more
doaj   +1 more source

Impact of Dietary Sugars on β-Cell Function

Diabetology, 2023
Regular consumption of dietary sugars can cause significant damage to the β-cells. Almost a century after the discovery of insulin, it has been suggested that the frequent consumption of certain carbohydrates can damage pancreatic β-cells, causing ...
Ananda Malta, Lucas Paulo Jacinto Saavedra, Scarlett Rodrigues Raposo, Gabriel Kian Guimarães Lopes, Maryana Debossan Fernandes, Letícia Ferreira Barbosa, Douglas Lopes Almeida, Paulo Cezar de Freitas Mathias   +7 more
doaj   +1 more source

Protein Restriction in the Peri-Pubertal Period Induces Autonomic Dysfunction and Cardiac and Vascular Structural Changes in Adult Rats

Frontiers in Physiology, 2022
Perturbations to nutrition during critical periods are associated with changes in embryonic, fetal or postnatal developmental patterns that may render the offspring more likely to develop cardiovascular disease in later life. The aim of this study was to
Anna Rebeka Oliveira Ferreira, Maiara Vanusa Guedes Ribeiro, Maria Natalia Chimirri Peres, Silvano Piovan, Géssica Dutra Gonçalves, Lucas Paulo Jacinto Saavedra, Juliana Nunes de Lima Martins, Marcos Divino Ferreira Junior, Keilah Valeria Naves Cavalcante, Gabriel kian Guimarães Lopes, Mariane Carneiro, Douglas Lopes Almeida, Rodrigo Mello Gomes, Jurandir Fernando Comar, James Andrew Armitage, Paulo Cezar de Freitas Mathias, Kesia Palma-Rigo, Kesia Palma-Rigo   +17 more
doaj   +1 more source

The Secrets of Acinetobacter Secretion [PDF]

Trends in Microbiology, 2017
Infections caused by the bacterial pathogen Acinetobacter baumannii are a mounting concern for healthcare practitioners as widespread antibiotic resistance continues to limit therapeutic treatment options. The biological processes used by A. baumannii to cause disease are not well defined, but recent research has indicated that secreted proteins may ...
Rachel L. Kinsella, Rachel L. Kinsella, Christian M. Harding, Brent S. Weber, Brent S. Weber, Mario F. Feldman   +5 more
openaire   +3 more sources

COVID-19 During Development: A Matter of Concern

Frontiers in Cell and Developmental Biology, 2021
A new infectious disease, COVID-19, has spread around the world. The most common symptoms of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection are cough and fever, but severe cases can develop acute respiratory distress syndrome. The
Lucas Paulo Jacinto Saavedra, Kelly Valério Prates, Gessica Dutra Gonçalves, Silvano Piovan, Paulo Matafome, Paulo Matafome, Paulo Matafome, Paulo Cezar de Freitas Mathias   +7 more
doaj   +1 more source

Comparative analysis of canine mesenchymal stem cells and bone marrow-derived mononuclear cells [PDF]

Veterinary World, 2021
Background and Aim: Mesenchymal stem cells (MSCs), which have multi-lineage differentiation potentials, are a promising source for regenerative medicine.
Noritaka Maeta, Katsutoshi Tamura, Fuuna Ezuka, Hiroshi Takemitsu   +3 more
doaj   +1 more source

Molecular and Cellular Bases of Lipodystrophy Syndromes

Frontiers in Endocrinology, 2022
Lipodystrophy syndromes are rare diseases originating from a generalized or partial loss of adipose tissue. Adipose tissue dysfunction results from heterogeneous genetic or acquired causes, but leads to similar metabolic complications with insulin ...
Jamila Zammouri, Camille Vatier, Camille Vatier, Emilie Capel, Martine Auclair, Caroline Storey-London, Elise Bismuth, Héléna Mosbah, Héléna Mosbah, Bruno Donadille, Bruno Donadille, Sonja Janmaat, Sonja Janmaat, Bruno Fève, Bruno Fève, Isabelle Jéru, Isabelle Jéru, Isabelle Jéru, Corinne Vigouroux, Corinne Vigouroux, Corinne Vigouroux   +20 more
doaj   +1 more source

Endogenous and Exogenous Regulatory Signaling in the Secretory Pathway: Role of Golgi Signaling Molecules in Cancer

Frontiers in Cell and Developmental Biology, 2022
The biosynthetic transport route that constitutes the secretory pathway plays a fundamental role in the cell, providing to the synthesis and transport of around one third of human proteins and most lipids.
Simona Del Giudice, Valentina De Luca, Seyedehnegar Parizadeh, Domenico Russo, Alberto Luini, Rosaria Di Martino   +5 more
doaj   +1 more source

Revealing the secrets of secretion

eLife, 2018
An intracellular ion channel may have a central role in the release of cytokines by macrophages.
Antony Galione, Lianne C Davis
openaire   +3 more sources