Results 131 to 140 of about 1,130,311 (339)
IDMF is a derivative of dimethyl fumarate (DMF) with a unique therapeutic potential at the intersection of psoriasis and multiple sclerosis. Here, we demonstrate that it compares favorably with DMF and its other derivatives, such as Diroximel, in the zebrafish, microglia, and lymphocyte models.
Yulin He+5 more
wiley +1 more source
V.—On the Physiological Actions of Drugs on the Secretion of Bile [PDF]
William F. Rutherford
openalex +1 more source
GPR142, a tryptophan‐sensing receptor, stimulates gastrointestinal hormones like ghrelin and is linked to inflammation regulation. Proinflammatory cytokines suppress ghrelin production, while tryptophan levels decrease via IDO1 activation. Our findings reveal that proinflammatory cytokines directly regulate GPR142 expression in ghrelin‐producing cells,
Yoko Ueda+15 more
wiley +1 more source
Hydrogen sulfide repairs testicular damage induced by heat stress in rats
Heat stress can cause testicular damage and affect fertility. We investigated the potential protective role of hydrogen sulfide (H2S) against heat stress‐induced testicular injury and observed that H2S donor NaHS can effectively restore testicular damage in rats by inhibiting inflammation and oxidative stress. Our results suggest that H2S might be used
Xinyu Guo+6 more
wiley +1 more source
This study aims to present a reconciliation model of bureaucratic principles (Secretion) and democracy (Transparency) through the mapping of public information about managing a local government budget which is accessible to the public and which ones are ...
I PUTU YOGA BUMI PRADANA
doaj
Demonstration of a Hatching Secretion in Rana Pipiens Schreber [PDF]
Kenneth W. Cooper
openalex +1 more source
T2DM is characterized by peripheral blood insulin resistance and progressive pancreatic β‐cell dysfunction. Here, we showed that AQP7, the only aquaglyceroporin protein, regulates autophagy and apoptosis in pancreatic β‐cells. We propose the existence of a positive feedback loop between MAPK signaling and AQP7 that regulates autophagy and apoptosis in ...
Maoqi Wang+5 more
wiley +1 more source
The tumor microenvironment is a dynamic, multifaceted complex system of interdependent cellular, biochemical, and biophysical components. Three‐dimensional in vitro models of the tumor microenvironment enable a better understanding of these interactions and their impact on cancer progression and therapeutic resistance.
Salma T. Rafik+3 more
wiley +1 more source
Lipoproteins in a nonrecirculating perfusate of rat liver
Rat livers were perfused in a nonrecirculating system for 30–40 min with Krebs-Ringer bicarbonate–0.1% glucose solution gassed with 95% O2–5% CO2 at 37°C at a flow rate of 3 ml/g/min.
Julian B. Marsh
doaj