Results 11 to 20 of about 2,579,679 (405)

The mechanism of HMGB1 secretion and release

Experimental and Molecular Medicine, 2022
High mobility group box 1 (HMGB1) is a nonhistone nuclear protein that has multiple functions according to its subcellular location. In the nucleus, HMGB1 is a DNA chaperone that maintains the structure and function of chromosomes.
Ruochan Chen, R. Kang, D. Tang
semanticscholar   +1 more source

Modulation of apoprotein E secretion in response to receptor-mediated endocytosis in resident and inflammatory macrophages. [PDF]

, 1984
We have determined the effect of various endocytic ligands on the secretion of ApoE by macrophages. ApoE was a major secreted protein of resident macrophages, but BCG-activated macrophages secreted little ApoE and periodate-elicited macrophages secreted ...
Takemura, R, Werb, Z
core   +2 more sources

Moderate Physical Training Ameliorates Cardiovascular Dysfunction Induced by High Fat Diet After Cessation of Training in Adult Rats

Frontiers in Physiology, 2019
We aimed to test whether moderate physical training can induce long-lasting protection against cardiovascular risk factors induced by high fat diet (HFD) intake, even after cessation of training.
Laize Peron Tófolo, Laize Peron Tófolo, Wilson Rinaldi, Adriane Barreto Gôngora, Camila Cristina Ianoni Matiusso, Audrei Pavanello, Ananda Malta, Douglas Lopes de Almeida, Tatiane Aparecida Ribeiro, Anna Rebeka Oliveira, Maria Natalia Chimirri Peres, James Andrew Armitage, Paulo Cezar de Freitas Mathias, Kesia Palma-Rigo, Kesia Palma-Rigo   +14 more
doaj   +1 more source

Hepatic inactivation of murine Surf4 results in marked reduction in plasma cholesterol

eLife, 2022
PCSK9 negatively regulates low-density lipoprotein receptor (LDLR) abundance on the cell surface, leading to decreased hepatic clearance of LDL particles and increased levels of plasma cholesterol.
Vi T Tang, Joseph McCormick, Bolin Xu, Yawei Wang, Huan Fang, Xiao Wang, David Siemieniak, Rami Khoriaty, Brian T Emmer, Xiao-Wei Chen, David Ginsburg   +10 more
doaj   +1 more source

Reduction in jejunal fluid absorption in vivo through distension and cholinergic stimulation not attributable to enterocyte secretion [PDF]

, 2018
Jejunal fluid absorption in vivo was reduced by distension and by hydrostatic pressure and further declined on adding E. coli STa enterotoxin but no net fluid secretion was detected.
Graham, V., Kenward, H., Lucas, M., McColl, S., McNaughton, E., Sabir, S., Tainsh, P., Turkington, C., Watson, P.   +8 more
core   +1 more source

Interaction of the Yersinia pestis type III regulatory proteins LcrG and LcrV occurs at a hydrophobic interface [PDF]

, 2002
BACKGROUND: Secretion of anti-host proteins by Yersinia pestis via a type III mechanism is not constitutive. The process is tightly regulated and secretion occurs only after an appropriate signal is received.
Matson, Jyl S, Nilles, Matthew L
core   +5 more sources

Aerobic Exercise Training Attenuates Tumor Growth and Reduces Insulin Secretion in Walker 256 Tumor-Bearing Rats

Frontiers in Physiology, 2018
Aerobic exercise training can improve insulin sensitivity in many tissues; however, the relationship among exercise, insulin, and cancer cell growth is unclear.
Veridiana Mota Moreira, Veridiana Mota Moreira, Veridiana Mota Moreira, Claudinéia Conationi da Silva Franco, Kelly Valério Prates, Rodrigo Mello Gomes, Rodrigo Mello Gomes, Ana Maria Praxedes de Moraes, Tatiane Aparecida Ribeiro, Isabela Peixoto Martins, Carina Previate, Audrei Pavanello, Camila Cristina Ianoni Matiusso, Douglas Lopes Almeida, Flávio Andrade Francisco, Ananda Malta, Laize Peron Tófolo, Laize Peron Tófolo, Laize Peron Tófolo, Sandra da Silva Silveira, Lucas Paulo Jacinto Saavedra, Katia Machado, Paulo Henrique Olivieri da Silva, Paulo Henrique Olivieri da Silva, Gabriel S. Fabrício, Kesia Palma-Rigo, Helenir Medri de Souza, Flaviane de Fátima Silva, Giuliana Regina Biazi, Taís Susane Pereira, Elaine Vieira, Rosiane Aparecida Miranda, Júlio Cezar de Oliveira, Luiz Delmar da Costa Lima, Wilson Rinaldi, Wilson Rinaldi, Maria Ida Ravanelli, Paulo Cezar de Freitas Mathias   +37 more
doaj   +1 more source

Growth Hormone (GH)-Releasing Peptide Stimulation of GH Release from Human Somatotroph Adenoma Cells: Interaction with GH-Releasing Hormone, Thyrotropin- Releasing Hormone, and Octreotide. [PDF]

, 1994
The synthetic hexapeptide GH-releasing peptide (GHRP; His-D-Trp-Ala-Trp-D-Phe-Lys-NH2) specifically stimulates GH secretion in humans in vivo and in animals in vitro and in vivo via a still unknown receptor and mechanism.
Brockmeier, S., Lange, M., Müller, Otto-Albrecht, Renner, U., Schopohl, Jochen, Stalla, G. K., Strasburger, Christian J., Werder, K. von   +7 more
core   +1 more source

A High Fat Diet during Adolescence in Male Rats Negatively Programs Reproductive and Metabolic Function Which Is Partially Ameliorated by Exercise

Frontiers in Physiology, 2017
An interaction between obesity, impaired glucose metabolism and sperm function in adults has been observed but it is not known whether exposure to a diet high in fat during the peri-pubertal period can have longstanding programmed effects on reproductive
Carlos A. Ibáñez, Carlos A. Ibáñez, Rafaela P. Erthal, Fernanda M. Ogo, Maria N. C. Peres, Henrique R. Vieira, Camila Conejo, Laize P. Tófolo, Flávio A. Francisco, Sandra da Silva Silveira, Ananda Malta, Audrei Pavanello, Isabela P. Martins, Paulo H. O. da Silva, Lucas Paulo Jacinto Saavedra, Gessica D. Gonçalves, Veridiana M. Moreira, Vander S. Alves, Claudinéia C. da Silva Franco, Carina Previate, Rodrigo M. Gomes, Renan de Oliveira Venci, Francielle R. S. Dias, James A. Armitage, Elena Zambrano, Paulo C. F. Mathias, Glaura S. A. Fernandes, Kesia Palma-Rigo   +27 more
doaj   +1 more source

Editorial: The secrets of secretion [PDF]

Journal of Leukocyte Biology, 2017
Discussion on neutrophil exocytosis and priming.
openaire   +3 more sources