Results 11 to 20 of about 1,882,580 (346)

Revealing the secrets of secretion

eLife, 2018
An intracellular ion channel may have a central role in the release of cytokines by macrophages.
Antony Galione, Lianne C Davis
openaire   +3 more sources

A High Fat Diet during Adolescence in Male Rats Negatively Programs Reproductive and Metabolic Function Which Is Partially Ameliorated by Exercise

Frontiers in Physiology, 2017
An interaction between obesity, impaired glucose metabolism and sperm function in adults has been observed but it is not known whether exposure to a diet high in fat during the peri-pubertal period can have longstanding programmed effects on reproductive
Carlos A. Ibáñez, Carlos A. Ibáñez, Rafaela P. Erthal, Fernanda M. Ogo, Maria N. C. Peres, Henrique R. Vieira, Camila Conejo, Laize P. Tófolo, Flávio A. Francisco, Sandra da Silva Silveira, Ananda Malta, Audrei Pavanello, Isabela P. Martins, Paulo H. O. da Silva, Lucas Paulo Jacinto Saavedra, Gessica D. Gonçalves, Veridiana M. Moreira, Vander S. Alves, Claudinéia C. da Silva Franco, Carina Previate, Rodrigo M. Gomes, Renan de Oliveira Venci, Francielle R. S. Dias, James A. Armitage, Elena Zambrano, Paulo C. F. Mathias, Glaura S. A. Fernandes, Kesia Palma-Rigo   +27 more
doaj   +1 more source

Moderate Physical Training Ameliorates Cardiovascular Dysfunction Induced by High Fat Diet After Cessation of Training in Adult Rats

Frontiers in Physiology, 2019
We aimed to test whether moderate physical training can induce long-lasting protection against cardiovascular risk factors induced by high fat diet (HFD) intake, even after cessation of training.
Laize Peron Tófolo, Laize Peron Tófolo, Wilson Rinaldi, Adriane Barreto Gôngora, Camila Cristina Ianoni Matiusso, Audrei Pavanello, Ananda Malta, Douglas Lopes de Almeida, Tatiane Aparecida Ribeiro, Anna Rebeka Oliveira, Maria Natalia Chimirri Peres, James Andrew Armitage, Paulo Cezar de Freitas Mathias, Kesia Palma-Rigo, Kesia Palma-Rigo   +14 more
doaj   +1 more source

Human aquaporin-11 guarantees efficient transport of H2O2 across the endoplasmic reticulum membrane

Redox Biology, 2020
Hydrogen peroxide (H2O2) is an essential second intracellular messenger. To reach its targets in the cytosol, H2O2 must cross a membrane, a feat that requires aquaporins (AQP) endowed with ‘peroxiporin’ activity (AQP3, AQP8, AQP9).
Stefano Bestetti, Mauro Galli, Ilaria Sorrentino, Paolo Pinton, Alessandro Rimessi, Roberto Sitia, Iria Medraño-Fernandez   +6 more
doaj   +1 more source

Small secreted proteins and exocytosis regulators: do they go along?

Plant Signaling & Behavior, 2023
Small secreted proteins play an important role in plant development, as well as in reactions to changes in the environment. In Arabidopsis thaliana, they are predominantly members of highly expanded families, such as the pathogenesis-related (PR) 1-like ...
Tamara Pečenková, Martin Potocký
doaj   +1 more source

Dance of The Golgi: Understanding Golgi Dynamics in Cancer Metastasis

Cells, 2022
The Golgi apparatus is at the center of protein processing and trafficking in normal cells. Under pathological conditions, such as in cancer, aberrant Golgi dynamics alter the tumor microenvironment and the immune landscape, which enhances the invasive ...
Rakhee Bajaj, Amanda N. Warner, Jared F. Fradette, Don L. Gibbons   +3 more
doaj   +1 more source

Aerobic Exercise Training Attenuates Tumor Growth and Reduces Insulin Secretion in Walker 256 Tumor-Bearing Rats

Frontiers in Physiology, 2018
Aerobic exercise training can improve insulin sensitivity in many tissues; however, the relationship among exercise, insulin, and cancer cell growth is unclear.
Veridiana Mota Moreira, Veridiana Mota Moreira, Veridiana Mota Moreira, Claudinéia Conationi da Silva Franco, Kelly Valério Prates, Rodrigo Mello Gomes, Rodrigo Mello Gomes, Ana Maria Praxedes de Moraes, Tatiane Aparecida Ribeiro, Isabela Peixoto Martins, Carina Previate, Audrei Pavanello, Camila Cristina Ianoni Matiusso, Douglas Lopes Almeida, Flávio Andrade Francisco, Ananda Malta, Laize Peron Tófolo, Laize Peron Tófolo, Laize Peron Tófolo, Sandra da Silva Silveira, Lucas Paulo Jacinto Saavedra, Katia Machado, Paulo Henrique Olivieri da Silva, Paulo Henrique Olivieri da Silva, Gabriel S. Fabrício, Kesia Palma-Rigo, Helenir Medri de Souza, Flaviane de Fátima Silva, Giuliana Regina Biazi, Taís Susane Pereira, Elaine Vieira, Rosiane Aparecida Miranda, Júlio Cezar de Oliveira, Luiz Delmar da Costa Lima, Wilson Rinaldi, Wilson Rinaldi, Maria Ida Ravanelli, Paulo Cezar de Freitas Mathias   +37 more
doaj   +1 more source

Endogenous and Exogenous Regulatory Signaling in the Secretory Pathway: Role of Golgi Signaling Molecules in Cancer

Frontiers in Cell and Developmental Biology, 2022
The biosynthetic transport route that constitutes the secretory pathway plays a fundamental role in the cell, providing to the synthesis and transport of around one third of human proteins and most lipids.
Simona Del Giudice, Valentina De Luca, Seyedehnegar Parizadeh, Domenico Russo, Alberto Luini, Rosaria Di Martino   +5 more
doaj   +1 more source

Editorial: The secrets of secretion [PDF]

Journal of Leukocyte Biology, 2017
Discussion on neutrophil exocytosis and priming.
openaire   +3 more sources

Gasdermin D is an executor of pyroptosis and required for interleukin-1β secretion

Cell Research, 2015
Inflammasome is an intracellular signaling complex of the innate immune system. Activation of inflammasomes promotes the secretion of interleukin 1β (IL-1β) and IL-18 and triggers pyroptosis.
Wan-ting He, H. Wan, Lichen Hu, Pengda Chen, Xin Wang, Zhe Huang, Zhang-Hua Yang, Chuan-Qi Zhong, Jiahuai Han   +8 more
semanticscholar   +1 more source