Results 11 to 20 of about 2,802,374 (388)

The mechanism of HMGB1 secretion and release

Experimental and Molecular Medicine, 2022
High mobility group box 1 (HMGB1) is a nonhistone nuclear protein that has multiple functions according to its subcellular location. In the nucleus, HMGB1 is a DNA chaperone that maintains the structure and function of chromosomes.
Ruochan Chen, R. Kang, D. Tang
semanticscholar   +1 more source

Small secreted proteins and exocytosis regulators: do they go along?

Plant Signaling & Behavior, 2023
Small secreted proteins play an important role in plant development, as well as in reactions to changes in the environment. In Arabidopsis thaliana, they are predominantly members of highly expanded families, such as the pathogenesis-related (PR) 1-like ...
Tamara Pečenková, Martin Potocký
doaj   +1 more source

Endogenous and Exogenous Regulatory Signaling in the Secretory Pathway: Role of Golgi Signaling Molecules in Cancer

Frontiers in Cell and Developmental Biology, 2022
The biosynthetic transport route that constitutes the secretory pathway plays a fundamental role in the cell, providing to the synthesis and transport of around one third of human proteins and most lipids.
Simona Del Giudice, Valentina De Luca, Seyedehnegar Parizadeh, Domenico Russo, Alberto Luini, Rosaria Di Martino   +5 more
doaj   +1 more source

Modulation of apoprotein E secretion in response to receptor-mediated endocytosis in resident and inflammatory macrophages. [PDF]

, 1984
We have determined the effect of various endocytic ligands on the secretion of ApoE by macrophages. ApoE was a major secreted protein of resident macrophages, but BCG-activated macrophages secreted little ApoE and periodate-elicited macrophages secreted ...
Takemura, R, Werb, Z
core   +2 more sources

Reduction in jejunal fluid absorption in vivo through distension and cholinergic stimulation not attributable to enterocyte secretion [PDF]

, 2018
Jejunal fluid absorption in vivo was reduced by distension and by hydrostatic pressure and further declined on adding E. coli STa enterotoxin but no net fluid secretion was detected.
Graham, V., Kenward, H., Lucas, M., McColl, S., McNaughton, E., Sabir, S., Tainsh, P., Turkington, C., Watson, P.   +8 more
core   +1 more source

Moderate Physical Training Ameliorates Cardiovascular Dysfunction Induced by High Fat Diet After Cessation of Training in Adult Rats

Frontiers in Physiology, 2019
We aimed to test whether moderate physical training can induce long-lasting protection against cardiovascular risk factors induced by high fat diet (HFD) intake, even after cessation of training.
Laize Peron Tófolo, Laize Peron Tófolo, Wilson Rinaldi, Adriane Barreto Gôngora, Camila Cristina Ianoni Matiusso, Audrei Pavanello, Ananda Malta, Douglas Lopes de Almeida, Tatiane Aparecida Ribeiro, Anna Rebeka Oliveira, Maria Natalia Chimirri Peres, James Andrew Armitage, Paulo Cezar de Freitas Mathias, Kesia Palma-Rigo, Kesia Palma-Rigo   +14 more
doaj   +1 more source

Human aquaporin-11 guarantees efficient transport of H2O2 across the endoplasmic reticulum membrane

Redox Biology, 2020
Hydrogen peroxide (H2O2) is an essential second intracellular messenger. To reach its targets in the cytosol, H2O2 must cross a membrane, a feat that requires aquaporins (AQP) endowed with ‘peroxiporin’ activity (AQP3, AQP8, AQP9).
Stefano Bestetti, Mauro Galli, Ilaria Sorrentino, Paolo Pinton, Alessandro Rimessi, Roberto Sitia, Iria Medraño-Fernandez   +6 more
doaj   +1 more source

A High Fat Diet during Adolescence in Male Rats Negatively Programs Reproductive and Metabolic Function Which Is Partially Ameliorated by Exercise

Frontiers in Physiology, 2017
An interaction between obesity, impaired glucose metabolism and sperm function in adults has been observed but it is not known whether exposure to a diet high in fat during the peri-pubertal period can have longstanding programmed effects on reproductive
Carlos A. Ibáñez, Carlos A. Ibáñez, Rafaela P. Erthal, Fernanda M. Ogo, Maria N. C. Peres, Henrique R. Vieira, Camila Conejo, Laize P. Tófolo, Flávio A. Francisco, Sandra da Silva Silveira, Ananda Malta, Audrei Pavanello, Isabela P. Martins, Paulo H. O. da Silva, Lucas Paulo Jacinto Saavedra, Gessica D. Gonçalves, Veridiana M. Moreira, Vander S. Alves, Claudinéia C. da Silva Franco, Carina Previate, Rodrigo M. Gomes, Renan de Oliveira Venci, Francielle R. S. Dias, James A. Armitage, Elena Zambrano, Paulo C. F. Mathias, Glaura S. A. Fernandes, Kesia Palma-Rigo   +27 more
doaj   +1 more source

The Role of Bile in the Regulation of Exocrine Pancreatic Secretion [PDF]

, 1992
As early as 1926 Mellanby (1) was able to show that introduction of bile into the duodenum of anesthetized cats produces a copious flow of pancreatic juice.
Adamczyk W, Andrén-Sandberg A, Aronchick CA, Björnsson OG, Björnsson OG, Brand SJ, Burhol PG, Davies HA, Dragstedt LR, Erlinger S, Eyre-Brook IA, Fausa O, Fiedler F, Forell MM, Forell MM, Forell MM, Forell MM, Forell MM, Frühauf S, Fölsch UR, Geratz JD, Gomez G, Green GM, Gries E, Grundy SM, Hanssen LE, Hartmann W, Hellmann G, Holtermuller KH, Holtermuller KH, Hotz J, Ivy AC, Kataoka K, Konturek SJ, Koop I, Koop I, Koop I, Koop I, Koop I, Kurosawa H, Kuroyanagi Y, Lagerlöf HO, Lehnert P, Lueth HC, Malagelada J-R, Malagelada J-R, Malagelada J-R, Mellanby J, Meyer JH, Miyasaka K, Miyasaka K, Miyasaka K, Miyasaka K, Nakamura R, Nakamura R, Namba M, Nustede R, Ohta H, Osnes M, Osnes M, Osnes M, Osnes M, Otte M, Peter Lehnert, Riepl RL, Riepl RL, Riepl RL, Riepl RL, Rudolf L. Riepl, Schaffalitzky de Muckadell OB, Shiratori K, Smallwood RA, Staub VL, Thomas JE, van Levan H, Wormsley KG   +75 more
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Aerobic Exercise Training Attenuates Tumor Growth and Reduces Insulin Secretion in Walker 256 Tumor-Bearing Rats

Frontiers in Physiology, 2018
Aerobic exercise training can improve insulin sensitivity in many tissues; however, the relationship among exercise, insulin, and cancer cell growth is unclear.
Veridiana Mota Moreira, Veridiana Mota Moreira, Veridiana Mota Moreira, Claudinéia Conationi da Silva Franco, Kelly Valério Prates, Rodrigo Mello Gomes, Rodrigo Mello Gomes, Ana Maria Praxedes de Moraes, Tatiane Aparecida Ribeiro, Isabela Peixoto Martins, Carina Previate, Audrei Pavanello, Camila Cristina Ianoni Matiusso, Douglas Lopes Almeida, Flávio Andrade Francisco, Ananda Malta, Laize Peron Tófolo, Laize Peron Tófolo, Laize Peron Tófolo, Sandra da Silva Silveira, Lucas Paulo Jacinto Saavedra, Katia Machado, Paulo Henrique Olivieri da Silva, Paulo Henrique Olivieri da Silva, Gabriel S. Fabrício, Kesia Palma-Rigo, Helenir Medri de Souza, Flaviane de Fátima Silva, Giuliana Regina Biazi, Taís Susane Pereira, Elaine Vieira, Rosiane Aparecida Miranda, Júlio Cezar de Oliveira, Luiz Delmar da Costa Lima, Wilson Rinaldi, Wilson Rinaldi, Maria Ida Ravanelli, Paulo Cezar de Freitas Mathias   +37 more
doaj   +1 more source