Results 41 to 50 of about 2,802,374 (388)

Dapagliflozin stimulates glucagon secretion at high glucose: experiments and mathematical simulations of human A-cells. [PDF]

open access: yes, 2016
Glucagon is one of the main regulators of blood glucose levels and dysfunctional stimulus secretion coupling in pancreatic A-cells is believed to be an important factor during development of diabetes.
Ahlstedt, I.   +3 more
core   +1 more source

Bacterial Secretion Systems: An Overview

open access: yesMicrobiology spectrum, 2016
Bacterial pathogens utilize a multitude of methods to invade mammalian hosts, damage tissue sites, and thwart the immune system from responding. One essential component of these strategies for many bacterial pathogens is the secretion of proteins across ...
Erin R Green, J. Mecsas
semanticscholar   +1 more source

Editorial: The secrets of secretion [PDF]

open access: yesJournal of Leukocyte Biology, 2017
Discussion on neutrophil exocytosis and priming.
openaire   +2 more sources

High-salinity growth conditions promote tat-independent secretion of tat substrates in Bacillus subtilis [PDF]

open access: yes, 2012
The Gram-positive bacterium Bacillus subtilis contains two Tat translocases, which can facilitate transport of folded proteins across the plasma membrane. Previous research has shown that Tat-dependent protein secretion in B.
Alami   +59 more
core   +1 more source

Short-Chain Fatty Acids Stimulate Glucagon-Like Peptide-1 Secretion via the G-Protein–Coupled Receptor FFAR2

open access: yesDiabetes, 2012
Interest in how the gut microbiome can influence the metabolic state of the host has recently heightened. One postulated link is bacterial fermentation of “indigestible” prebiotics to short-chain fatty acids (SCFAs), which in turn modulate the release of
G. Tolhurst   +9 more
semanticscholar   +1 more source

Morphology of the Female Receptaculum Seminis of Euschistus heros (FABRICIUS, 1798) (INSECTA: HEMIPTERA: PENTATOMIDAE) [PDF]

open access: yesAnais da Academia Brasileira de Ciências
Euschistus heros (Fabricius, 1798) (Heteroptera: Pentatomidae) is a soybean pest in Brazil. It has a reproductive success that may be associated with the female receptaculum seminis or spermatheca, a reproductive organ for spermatozoa storage until the ...
EDMILSON A. SOUZA   +4 more
doaj   +1 more source

Ferritin heavy chain Is the host factor responsible for HCV-Induced inhibition of apoB-100 production and is required for efficient viral infection [PDF]

open access: yes, 2012
Hepatic fat export occurs by apolipoprotein B-100-containing lipoprotein production, whereas impaired production leads to liver steatosis. Hepatitis C virus (HCV) infection is associated to dysregulation of apoB-100 secretion and steatosis; however, the ...
AMICONE, Laura   +9 more
core   +3 more sources

Hepatic inactivation of murine Surf4 results in marked reduction in plasma cholesterol

open access: yeseLife, 2022
PCSK9 negatively regulates low-density lipoprotein receptor (LDLR) abundance on the cell surface, leading to decreased hepatic clearance of LDL particles and increased levels of plasma cholesterol.
Vi T Tang   +10 more
doaj   +1 more source

Controlling secretion to limit chemoresistance [PDF]

open access: yes, 2016
The tumor microenvironment influences cancer progression and therapy outcome by mechanisms not yet fully understood. In this issue, Bent et al. (2016) show how chemotherapy causes endothelial senescence.
Georgilis, A, Gil, J
core   +1 more source

Challenges and Pitfalls in the Engineering of Human Interleukin 22 (hIL-22) Secreting Lactobacillus reuteri

open access: yesFrontiers in Bioengineering and Biotechnology, 2020
Engineered microbes for the delivery of intestinally directed therapeutics is a promising avenue for the treatment of various intestinal diseases including inflammatory bowel disease (IBD) and intestinal graft vs. host disease (GVHD).
Laura Ortiz-Velez   +5 more
doaj   +1 more source

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