Results 61 to 70 of about 1,882,580 (346)

Phosphate acts directly on the calcium-sensing receptor to stimulate parathyroid hormone secretion

open access: yesNature Communications, 2019
Extracellular phosphate regulates its own renal excretion by eliciting concentration-dependent secretion of parathyroid hormone (PTH). However, the phosphate-sensing mechanism remains unknown and requires elucidation for understanding the aetiology of ...
Patricia P. Centeno   +7 more
semanticscholar   +1 more source

Novel and unscrutinized immune entities of the zebrafish gut

open access: yesFEBS Letters, EarlyView.
Understudied cells of the zebrafish immune system include bona fide immune cells and epithelial (‐derived) cells with immune functions. Research focusing on zebrafish cells which demonstrate similarities to mammalian immune cell counterparts may help us understand the pathologies in which they are implicated. Currently available and advanced tools make
Audrey Inge Schytz Andersen‐Civil   +5 more
wiley   +1 more source

From lactation to malignancy: A comparison between healthy and cancerous breast gland at single‐cell resolution reveals new issues for tumorigenesis

open access: yesFEBS Letters, EarlyView.
Single‐cell RNA sequencing reveals an opposite role of SLPI in basal tumors based on metastatic spread, along with shared activation of specific regulons in cancer cells and mature luminal lactocytes, as well as downregulation of MALAT1 and NEAT1 in the latter.
Pietro Ancona   +4 more
wiley   +1 more source

The pathophysiology of intestinal lipoprotein production

open access: yesFrontiers in Physiology, 2015
Intestinal lipoprotein production is a multistep process, essential for the absorption of dietary fats and fat-soluble vitamins. Chylomicron assembly begins in the endoplasmic reticulum with the formation of primordial, phospholipids-rich particles that ...
Antonina eGiammanco   +3 more
doaj   +1 more source

Differentiation of Trafficking Pathways at Golgi Entry Core Compartments and Post-Golgi Subdomains

open access: yesFrontiers in Plant Science, 2020
Eukaryotic cells have developed specialized membrane structures called organelles, which compartmentalize cellular functions and chemical reactions. Recent improvements in microscopy and membrane compartment isolation techniques are now sophisticating ...
Yoko Ito, Yohann Boutté
doaj   +1 more source

Secret of Life, Secret of Death [PDF]

open access: yesRomanian Journal of Psychoanalysis, 2020
Abstract From his first Freudian studies, but especially in S. Freud’s correspondence with W. Fliess, the term “secret” (geheim, geheimnis) appears frequently, hence its weight and significance in psychic life, and implicitly as a form of intimacy and of confidentiality shared in the analytical relationship.
openaire   +2 more sources

Imeglimin attenuates liver fibrosis by inhibiting vesicular ATP release from hepatic stellate cells

open access: yesFEBS Letters, EarlyView.
Imeglimin, at clinically relevant concentrations, inhibits vesicular ATP accumulation and release from hepatic stellate cells, thereby attenuating purinergic signaling and reducing fibrogenic activation. This mechanism reveals a newly identified antifibrotic action of imeglimin beyond glycemic control.
Seiji Nomura   +8 more
wiley   +1 more source

Transport and recycling of radiocesium in the alimentary tract of reindeer

open access: yesRangifer, 1990
Transport of radiocesium between the body pools and the alimentary tract was studied in 7 reindeer calves. Comparisons were made between reindeer receiving the Cs- binder Prussian blue (Ammon-ium-ironhexacyanoferrate) and untreated animals.
Hans Staaland   +2 more
doaj   +1 more source

Secrets of a Secretin [PDF]

open access: yesStructure, 2013
Secretins are major constituents of bacterial type III secretion systems (T3SS). In this issue of Structure, Kowal and colleagues report on the cryo-EM structure of the native YscC secretin from Yersinia, revealing its internal symmetry and mode of length adaptation.
openaire   +3 more sources

Type V Secretion Systems: An Overview of Passenger Domain Functions

open access: yesFrontiers in Microbiology, 2019
Bacteria secrete proteins for different purposes such as communication, virulence functions, adhesion to surfaces, nutrient acquisition, or growth inhibition of competing bacteria.
Ina Meuskens   +3 more
semanticscholar   +1 more source

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