Results 81 to 90 of about 1,130,311 (339)

Targeted metabolomics reveals novel diagnostic biomarkers for colorectal cancer

open access: yesMolecular Oncology, EarlyView.
This study employed targeted metabolomic profiling to identify 302 distinct metabolites present in platelet‐rich plasma (PRP), revealing aberrant metabolic profiles amongst individuals diagnosed with colorectal cancer (CRC). Compared to carcinoembryonic antigen (CEA) and cancer antigen 19‐9 (CA199), our metabolite panel showed improved sensitivity ...
Zuojian Hu   +7 more
wiley   +1 more source

Milk lipid secretion: recent biomolecular aspects

open access: yesBiomolecular Concepts, 2012
Neonates of most species depend on milk lipids for calories, fat-soluble vitamins, and bioactive lipid components for growth and development during the postnatal period.
McManaman James L.
doaj   +1 more source

Challenges and Pitfalls in the Engineering of Human Interleukin 22 (hIL-22) Secreting Lactobacillus reuteri

open access: yesFrontiers in Bioengineering and Biotechnology, 2020
Engineered microbes for the delivery of intestinally directed therapeutics is a promising avenue for the treatment of various intestinal diseases including inflammatory bowel disease (IBD) and intestinal graft vs. host disease (GVHD).
Laura Ortiz-Velez   +5 more
doaj   +1 more source

A Recursive Threshold Visual Cryptography Scheme [PDF]

open access: yesarXiv, 2009
This paper presents a recursive hiding scheme for 2 out of 3 secret sharing. In recursive hiding of secrets, the user encodes additional information about smaller secrets in the shares of a larger secret without an expansion in the size of the latter, thereby increasing the efficiency of secret sharing.
arxiv  

Respiratory complex I‐mediated NAD+ regeneration regulates cancer cell proliferation through the transcriptional and translational control of p21Cip1 expression by SIRT3 and SIRT7

open access: yesMolecular Oncology, EarlyView.
NAD+ regeneration by mitochondrial complex I NADH dehydrogenase is important for cancer cell proliferation. Specifically, NAD+ is necessary for the activities of NAD+‐dependent deacetylases SIRT3 and SIRT7, which suppress the expression of p21Cip1 cyclin‐dependent kinase inhibitor, an antiproliferative molecule, at the translational and transcriptional
Masato Higurashi   +5 more
wiley   +1 more source

Membrane traffic and fusion at post-Golgi compartments

open access: yesFrontiers in Plant Science, 2012
Complete sequencing of the Arabidopsis genome a decade ago has facilitated the functional analysis of various biological processes including membrane traffic by which many proteins are delivered to their sites of action and turnover.
Misoon ePark, Gerd eJürgens
doaj   +1 more source

On ASGS framework: general requirements and an example of implementation [PDF]

open access: yesarXiv, 2002
In the paper we propose general framework for Automatic Secret Generation and Sharing (ASGS) that should be independent of underlying secret sharing scheme. ASGS allows to prevent the dealer from knowing the secret or even to eliminate him at all. Two situations are discussed.
arxiv  

Response to neoadjuvant chemotherapy in early breast cancers is associated with epithelial–mesenchymal transition and tumor‐infiltrating lymphocytes

open access: yesMolecular Oncology, EarlyView.
Epithelial–mesenchymal transition (EMT) and tumor‐infiltrating lymphocytes (TILs) are associated with early breast cancer response to neoadjuvant chemotherapy (NAC). This study evaluated EMT and TIL shifts, with immunofluorescence and RNA sequencing, at diagnosis and in residual tumors as potential biomarkers associated with treatment response.
Françoise Derouane   +16 more
wiley   +1 more source

Extracellular proteins: Novel key components of metal resistance in cyanobacteria?

open access: yesFrontiers in Microbiology, 2016
Metals are essential for all living organisms and required for fundamental biochemical processes. However, when in excess, metals can turn into highly-toxic agents able to disrupt cell membranes, alter enzymatic activities and damage DNA.
Joaquin eGiner-Lamia   +11 more
doaj   +1 more source

Sniffing for Codebase Secret Leaks with Known Production Secrets in Industry [PDF]

open access: yesarXiv, 2020
Leaked secrets, such as passwords and API keys, in codebases were responsible for numerous security breaches. Existing heuristic techniques, such as pattern matching, entropy analysis, and machine learning, exist to detect and alert developers of such leaks.
arxiv  

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