Stem cell secretome derived from human amniotic fluid affords neuroprotection in an ischemic model
Human amniotic fluid stem cells (hAFSCs) are growing in interest; yet, little is understood about their secretome and neuroprotective actions in different diseases, including stroke.
Chase Kingsbury, Liborio Stuppia
doaj +1 more source
VerSeDa: vertebrate secretome database [PDF]
Based on the current tools, de novo secretome (full set of proteins secreted by an organism) prediction is a time consuming bioinformatic task that requires a multifactorial analysis in order to obtain reliable in silico predictions. Hence, to accelerate this process and offer researchers a reliable repository where secretome information can be ...
Cortázar, Ana R. +3 more
openaire +4 more sources
Secretome Proteomic Approaches for Biomarker Discovery: An Update on Colorectal Cancer
Searching for new cancer-related biomarkers is a key priority for the early detection of solid tumors, such as colorectal cancer (CRC), in clinically relevant biological fluids.
Armando Cevenini +2 more
doaj +1 more source
Chloride intracellular channel 3: a secreted pro-invasive oxidoreductase [PDF]
No abstract ...
Norman, Jim, Zanivan, Sara
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Mesenchymal Stem Cell Secretome for Dermatology Application: A Review
Restu Harisma Damayanti, Taofik Rusdiana, Nasrul Wathoni Department of Pharmaceutics and Pharmaceutical Technology, Faculty of Pharmacy, Universitas Padjadjaran, Sumedang, 45353, IndonesiaCorrespondence: Nasrul WathoniDepartment of Pharmaceutics and ...
Damayanti RH, Rusdiana T, Wathoni N
doaj
Background The mechanisms underpinning the regenerative capabilities of mesenchymal stem cells (MSC) were originally thought to reside in their ability to recognise damaged tissue and to differentiate into specific cell types that would replace defective
Robert Mitchell +18 more
doaj +1 more source
Development of 'Redox Arrays' for identifying novel glutathionylated proteins in the secretome [PDF]
Proteomics techniques for analysing the redox status of individual proteins in complex mixtures tend to identify the same proteins due to their high abundance.
Bottazzi, Barbara +6 more
core +1 more source
Cell Secretome: Basic Insights and Therapeutic Opportunities for CNS Disorders
Transplantation of stem cells, in particular mesenchymal stem cells (MSCs), stands as a promising therapy for trauma, stroke or neurodegenerative conditions such as spinal cord or traumatic brain injuries (SCI or TBI), ischemic stroke (IS), or Parkinson
Andreia G. Pinho +4 more
doaj +1 more source
How shall we use the proteomics toolbox for biomarker discovery? [PDF]
Biomarker discovery for clinical purposes is one of the major areas in which proteomics is used. However, despite considerable effort, the successes have been relatively scarce.
Hochstrasser, Denis +2 more
core +5 more sources
Microfluidics-based liquid chromatography/mass spectrometry multiple reaction monitoring approach for the relative quantification of Burkholderia cenocepacia secreted virulence factors [PDF]
Rationale: Burkholderia cenocepacia is an opportunistic pathogen that is commonly isolated from patients with cystic fibrosis (CF). Quorum sensing has been suggested to play a role in the activity of type II and type VI secretion systems and the release ...
Daled, Simon +6 more
core +2 more sources

