Results 41 to 50 of about 61,645 (272)

Indicators from archaeal secretomes

Microbiological Research, 2010
Just as in the Eukarya and the Bacteria, members of the Archaea need to export proteins beyond the cell membrane. This would be required to fulfill a variety of essential functions such as nutrient acquisition and biotransformations, maintenance of extracellular structures and more.
Saleh, Mazen, Song, Catharine, Nasserulla, Sabah, Leduc, L.G.   +3 more
openaire   +2 more sources

A proteomic atlas of senescence-associated secretomes for aging biomarker development. [PDF]

, 2020
The senescence-associated secretory phenotype (SASP) has recently emerged as a driver of and promising therapeutic target for multiple age-related conditions, ranging from neurodegeneration to cancer.
Basisty, Nathan, Campisi, Judith, Ferrucci, Luigi, Holtz, Anja, Jeon, Ok Hee, Kale, Abhijit, Kuehnemann, Chisaka, Payne, Therese, Rao, Chirag, Schilling, Birgit, Shah, Samah, Sharma, Vagisha   +11 more
core   +1 more source

The Salivary Secretome

, 2023
Recently, proteomics has emerged as an important tool for understanding biological systems, protein–protein interactions, and networks that ultimately lead to a deeper understanding of the underlying mechanisms of certain diseases. More recently, the study of secretomes, a type of proteomics, has also been highlighted as a potential next step in the ...
Luís, Perpétuo,, Rita, Ferreira,, Sofia, Guedes,, Francisco, Amado,, Rui, Vitorino,   +4 more
openaire   +3 more sources

Oral cancer secretome: Identification of cancer-associated proteins [PDF]

, 2014
This study aims to identify cancer-associated proteins in the secretome of oral cancer cell lines. We have successfully established four primary cell cultures of normal cells with a limited lifespan without human telomerase reverse transcriptase (hTERT ...
Chang, H. Y., Cheong, S. C., Hor, S. Y., Karsani, S. A., Lim, K. P., Rahman, M. A., Zain, R. B.   +6 more
core   +1 more source

FunSecKB: the Fungal Secretome KnowledgeBase [PDF]

Database, 2011
The Fungal Secretome KnowledgeBase (FunSecKB) provides a resource of secreted fungal proteins, i.e. secretomes, identified from all available fungal protein data in the NCBI RefSeq database. The secreted proteins were identified using a well evaluated computational protocol which includes SignalP, WolfPsort and Phobius for signal peptide or subcellular
Lum, Gengkon, Min, Xiang Jia
openaire   +2 more sources

Proteomics of industrial fungi: trends and insights for biotechnology [PDF]

, 2010
Filamentous fungi are widely known for their industrial applications, namely, the production of food-processing enzymes and metabolites such as antibiotics and organic acids.
Oliveira, J.M., Graaff, L.H., de
core   +1 more source

Introductory editorial: drug-eluting stents or drug-eluting grafts? Insights from proteomic analysis [PDF]

, 2017
No abstract ...
Al-Attar, Nawwar, Coccia, Raffaella, Di Domenico, Fabio, Nappi, Francesco, Perluigi, Marzia, Spadaccio, Cristiano   +5 more
core   +1 more source

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

Molecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix, Daniel Samaga, Katharina Gehr, Benedek Dankó, Mohamed Schumann, Guido Drexler, Ahmed Alnatsha, Georg Beyer, Ujjwal Mahajan, Martin Selmansberger, Julia Mayerle, Claus Belka, Horst Zitzelsberger, Kirsten Lauber   +13 more
wiley   +1 more source

RIPK4 function interferes with melanoma cell adhesion and metastasis

Molecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski, Sławomir Lasota, Ewelina Madej, Anna A. Brożyna, Małgorzata Szczygieł, Agnieszka Harazin‐Lechowska, Jan Czerbniak, Janusz Rys, Jaroslaw Czyz, Agnieszka Wolnicka‐Glubisz   +9 more
wiley   +1 more source

The Zebrafish Secretome

Zebrafish, 2008
The secretome is a functionally rich proteome subset, including cellular membrane and extracellular proteins processed through the secretory pathway. In this study, Danio rerio and Homo sapiens RefSeq proteins were analyzed with SignalP, TargetP, Phobius, and pTarget algorithms.
openaire   +3 more sources