Results 81 to 90 of about 46,674 (254)

Kingdom-wide analysis of fungal small secreted proteins (SSPs) reveals their potential role in host association

Frontiers in Plant Science, 2016
Fungal secretome consists of various functional groups of proteins, many of which participate in nutrient acquisition, self-protection, or manipulation of the environment and neighboring organisms.
Ki-Tae eKim, Ki-Tae eKim, Jongbum eJeon, Jongbum eJeon, Jaeyoung eChoi, Jaeyoung eChoi, Kyeongchae eCheong, Kyeongchae eCheong, Hyeunjeong eSong, Hyeunjeong eSong, Gobong eChoi, Gobong eChoi, Seogchan eKang, Yong-Hwan eLee, Yong-Hwan eLee, Yong-Hwan eLee, Yong-Hwan eLee   +16 more
doaj   +1 more source

HCSD: the human cancer secretome database [PDF]

, 2015
The human cancer secretome database (HCSD) is a comprehensive database for human cancer secretome data. The cancer secretome describes proteins secreted by cancer cells and structuring information about the cancer secretome will enable further analysis ...
Amir Feizi, Jens Nielsen, Banaei Esfahani, Amir, Nielsen, Jens, Amir Banaei-esfahani, Feizi, Amir,, Nielsen, Jens B, Banaei Esfahani, Amir,, Feizi, Amir, Banaei-Esfahani, Amir, Nielsen, Jens B,, Nielsen, Jens B.   +11 more
core   +1 more source

Mechanically Regulated Secretion: How Physical Forces Instruct the Secretory Pathway and Remodel the Secretome

Advanced Science, EarlyView.
Mechanical cues, including ECM stiffness, stretch, compression, shear stress, and traction forces, remodel trafficking across the secretory pathway, from the ER and Golgi to endolysosomal compartments and the plasma membrane. The resulting secretome reshapes ECM composition and tissue mechanics, establishing feedback loops that support homeostasis or ...
Domenico Russo, Seetharaman Parashuraman, Maria Luigia Maresca, Angela Francesca Dinoi, Alessia Calcagnì, Riccardo Rizzo   +5 more
wiley   +1 more source

Global Secretome Characterization of the Pathogenic Yeast Candida glabrata

, 2019
Secretory proteins are key modulators of host–pathogen interaction. The human opportunistic fungal pathogen Candida glabrata lacks secreted proteolytic activity but possesses 11 glycosylphosphatidylinositol-anchored aspartyl proteases, also referred to ...
Rupinder Kaur (142108), Mubashshir Rasheed (7610936), Naveen Kumar (66313)   +2 more
core   +2 more sources

Mononuclear cell secretome protects from experimental autoimmune myocarditis [PDF]

, 2013
AimsSupernatants of serum-free cultured mononuclear cells (MNC) contain a mix of immunomodulating factors (secretome), which have been shown to attenuate detrimental inflammatory responses following myocardial ischaemia.
Gyöngyösi, Mariann, Hacker, Stefan, Kollmann, Dagmar, Hendrik Jan Ankersmit, Gabriel, Christian, Michael Mildner, Stefan Hacker, Matthias Zimmermann, Balazs Hegedus, Hoetzenecker, Wolfram, Schweiger, Thomas, Dagmar Kollmann, Mildner, Michael, Christian Gabriel, Zimmermann, Matthias, Konrad Hoetzenecker, Blyszczuk, Przemyslaw, Thomas Schweiger, Ankersmit, Hendrik Jan L., Eriksson, Urs, Hegedus, Balazs, Urs Eriksson, Andreas Mitterbauer, Ankersmit, Hendrik Jan, Peter Birner, Hoetzenecker, Konrad, Przemyslaw Blyszczuk, Wolfram Hoetzenecker, Hötzenecker, Konrad, Mitterbauer, Andreas, Birner, Peter, Mariann Gyöngyösi, Pavone-Gyöngyösi, Mariann, Hegedus B, Birner P, Eriksson U, Hoetzenecker W, Gabriel C, Zimmermann M, Mildner M, Kollmann D, Schweiger T, Mitterbauer A, Ankersmit HJ, Blyszczuk P, Hacker S, Hoetzenecker K, Gyöngyösi M   +47 more
core   +1 more source

Orthogonal Light‐ and Enzyme‐Triggered and‐Gate Prodrugs for Senolytic Therapy

Advanced Science, EarlyView.
An orthogonal AND‐gate prodrug platform combines 390 nm near‐UV photocleavage with SA‐β‐gal activation to control payload release in senescent cells. Its modular architecture enables 4‐MU fluorescence, doxorubicin‐mediated cytotoxicity, and ARV‐771‐driven BRD4 degradation, supporting stimulus‐controlled senolytic design in cellular and organoid models.
Mengyang Chang, Kaixue Zhang, Junwei Wang, Fangchao Bi, Zhuoxin Dai, Miao Yang, Ming Liu, Huanzhi Peng, Franklin Zhang, Yuan Guo, Jigang Dai, Quanxing Liu, Wei Wang   +12 more
wiley   +1 more source

RETRACTED ARTICLE: Human fetal skin-derived stem cell secretome enhances radiation-induced skin injury therapeutic effects by promoting angiogenesis

Stem Cell Research & Therapy, 2019
Background Radiation dermatitis is a refractory skin injury caused by radiotherapy. Human fetal skin-derived stem cell (hFSSC) is a preferable source for cell therapy and skin tissue regeneration.
Xiaoli Rong, Jiannan Li, Yanyan Yang, Liyan Shi, Tiechao Jiang   +4 more
doaj   +1 more source

Secretome analysis of V. inaequalis.

, 2013
Comparative analysis of secretome sizes of various filamentous fungi (A), showing that the secretome size of V. inaequalis is comparable to other fungi. Gene Ontology (GO) term assignments to V.
Vandna Chawla (103030), Mohit Kumar Swarnkar (103034), Karnika Thakur (103028), Ravi Shankar (103040), Gopaljee Jha (93565), Shammi Bhatti (103031), Jagdeep Kaur (103037)   +6 more
core   +1 more source

A Dual‐Functional Nanoplatform Targeting the dsDNA–cGAS Axis to Mitigate Disc Degeneration and Aberrant Innervation

Advanced Science, EarlyView.
RU@PEI‐ZIF integrates dsDNA scavenging with local cGAS inhibition to suppress the dsDNA–cGAS–STING/Netrin‐1 axis in intervertebral disc degeneration. By attenuating nucleus pulposus cell senescence, inflammatory and matrix‐catabolic responses, and pathological sensory innervation, this dual‐functional nanoplatform preserves disc integrity and reduces ...
Zhaojun He, Tianyu Chen, Zezheng Liu, Xinlin Huang, Ruitangbin Jiang, Yihao Liu, Baojing Xu, Yuxiang Li, Kangning Zhao, Huibo Yan, Lei Zhou, Can Liu, Qingchu Li   +12 more
wiley   +1 more source

Effects of Adipose-Derived Mesenchymal Stem Cell-Secretome on Pyroptosis of Laparoscopic Hepatic Ischemia Reperfusion Injury in a Porcine Model

Cells
Extensive research has been conducted on mesenchymal stem cells (MSCs) regarding their ability to modify the immune response and reduce tissue damage. Many researchers have found that the regulatory capacity of MSCs primarily comes from their secretome ...
Yajun Ma, Lei Cao, Pujun Li, Zhihui Jiao, Xiaoning Liu, Xiangyu Lu, Tao Liu, Hongbin Wang   +7 more
doaj   +1 more source