Results 91 to 100 of about 377,050 (209)
Scotty: lattice coincidences for macromolecular crystallographic phasing
Acta Crystallographica Section D, Volume 82, Issue 7, Page 813-823, July 2026.Scotty is a tool that leverages Niggli‐cell matches to identify similar crystallographic lattices and perform phasing with difference Fourier methods.When a macromolecular crystal lattice targeted for study is closely related to a previously studied crystal lattice, phasing the target crystal by difference (fast‐)Fourier transform (DFFT) methods is ...
Airlie J. McCoy +3 more
wiley +1 more source
Journal of Lipid Research, 2003 There is good evidence that the n-3 polyunsaturated fatty acids (PUFAs) in fish oil have antiinflammatory effects and reduce the pathogenesis of atherosclerosis. However, the mechanisms underlying these actions are largely unknown.
Souad Bousserouel +4 more
doaj +1 more source
Scotty: lattice coincidences in the Protein Data Bank
Acta Crystallographica Section D, Volume 82, Issue 7, Page 824-835, July 2026.Scotty supports crystallographic comparisons of lattice coincidences, the interpretation of oligomeric assemblies and paracrystallinity.The application Scotty, implemented within the Phasertng codebase, was used to perform a PDB‐wide analysis of lattice coincidences.
Airlie J. McCoy +3 more
wiley +1 more source
, 2010 Infected macrophages by dengue virus will produce phospholipase-A2 (PLA2) enzyme, that can promote arachidonic acid metabolism that produce inflammatory mediators, causing endhothelial damage and severe plasma leakage.
Hidayati, Wiyanda +2 more
core +1 more source
Toxins, 2016 Secretory phospholipase A2 (sPLA2) is known as a major component of snake venoms and displays higher-order catalytic hydrolysis functions as well as a wide range of pathological effects.
He Wang +5 more
doaj +1 more source
Proteolytic remodelling of the extracellular matrix by pericytes
The FEBS Journal, Volume 293, Issue 13, Page 3899-3953, July 2026.Pericytes are specialised perivascular cells intimately connected with endothelial cells and essential for the maintenance of vascular beds. They contribute to the formation and remodelling of the extracellular matrix by actively secreting proteases and protease inhibitors.
Tina Burkhard +4 more
wiley +1 more source
Bioconjugation Strategies for Revealing the Roles of Glycerophospholipids in Cells
ChemBioChem, Volume 27, Issue 11, 15 June 2026.Glycerophospholipids are the main class of phospholipids, essential for membrane structure, compartmentalization, and cellular signaling. To study their roles, innovative probes and advanced bioconjugation strategies have been developed, including by de novo lipid synthesis and bioorthogonal conjugation chemistry.
Brice Beauvais +5 more
wiley +1 more source
Journal of Lipid Research, 1998 The tumor promoter 12-O-tetradecanoylphorbol 13-acetate (TPA) stimulated the release of arachidonic acid (AA) from mouse keratinocytes. A distinct difference was observed between the fatty acid release profile elicited by TPA and other stimuli.
Bangyan Li-Stiles +2 more
doaj +1 more source
Inhibition of the activity of pro-inflammatory secretory phospholipase A2 by acute phase proteins
Mediators of Inflammation, 1996 Pro-Inflammatory non-pancreatic phospholipase A2 (sPLA2) is markedly over-expressed in acute systemic and chronic local inflammatory processes. Since in acute phase reaction sPLA2 is often over-expressed simultaneously with acute phase proteins (APP), it
W. Pruzanski, E. Stefanski, P. Vadas
doaj +1 more source
Role of secretory and cytosolic phospholipase A2 enzymes in lysophosphatidylcholine-stimulated monocyte arachidonic acid release [PDF]
, 2003 To determine if lysophosphatidylcholine (lysoPC) is able to induce proinflammatory changes in monocytes, its ability to stimulate arachidonic acid (AA) release, a product of phospholipase A2 (PLA2) activity, has been analyzed. LysoPC increased AA release
Oestvang, Janne +5 more
core +1 more source