Results 71 to 80 of about 2,362,291 (310)

Impact of the quality of organic amendments on size and composition of the weed seed bank [PDF]

, 2011
In addition to improving the soil quality, organic amendments of soils may affect weed seed survival, emergence, growth and reproduction. This study evaluated the effects of applications of different qualities of organic amendments on size and ...
Bulcke, Robert, Cougnon, Mathias, D'Hose, Tommy, De Cauwer, Benny, Leroy, Brecht, Reheul, Dirk   +5 more
core   +1 more source

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

Molecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller, Susanne Ebner, Carmen Haselrieder, Julia K. Günther, Astrid Drasche, Sophie Strich, Chiara Volani, Andrea Medici, Aleksandar Nikolajevic, Alex Deltedesco, Johannes E. Sigmund, Michael J. Blumer, Martin Hermann, Johanna Vanacker, Gerald Brandacher, Eduard Stefan, Omar Torres‐Quesada, Jakob Troppmair   +17 more
wiley   +1 more source

Exploring selection signatures in the divergence and evolution of lipid droplet (LD) associated genes in major oilseed crops

BMC Genomics
Background Oil bodies or lipid droplets (LDs) in the cytosol are the subcellular storage compartments of seeds and the sites of lipid metabolism providing energy to the germinating seeds.
Ramya Parakkunnel, Bhojaraja Naik K, Girimalla Vanishree, Anjitha George, Sripathy KV, Aruna YR, Udaya Bhaskar K, A Anandan, Sanjay Kumar   +8 more
doaj   +1 more source

LINC01116, a hypoxia‐lncRNA marker of pathological lymphangiogenesis and poor prognosis in lung adenocarcinoma

Molecular Oncology, EarlyView.
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola, Rafael Lopes Goncalves, Marin Truchi, Caroline Lacoux, Célia Scribe, Hugo Cadis, Laetitia Guardini, Sophie Bekisz, Marius Ilié, Paul Hofman, Georges Vassaux, Bernard Mari, Roger Rezzonico   +12 more
wiley   +1 more source

Drip fertigation improves cumin productivity, essential oil content, water use efficiency and profitability in arid zones of Rajasthan

Scientific Reports
In Rajasthan’s arid tracts, sandy soils and high evaporative demand limit border irrigation, making drip irrigation a sustainable alternative to enhance crop productivity by “feeding the plant, not the soil.” To understand the efficacy of drip ...
Ravindra Singh, C. B. Harisha, Sharda Choudhary, Y. Ravi, N. K. Meena, Ram Swaroop Meena, Suresh Kumar, A. K. Verma   +7 more
doaj   +1 more source

Production of organic seed for the organic sector (OF0154) [PDF]

, 2000
This is the final report of Defra project OF0154. Under the European Union Regulation on the organic production of agricultural products (2092/91), crops raised in organic systems should be grown from organically produced seed or vegetative material ...
Wolfe, Prof Martin
core  

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

Molecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone, James Dunford, Eleanor Calcutt, Vicki Gamble, Filiz Senbabaoglu Aksu, Lorena Ligammari, Georgina Wherry, Giorgia Gaeta, John C. Christianson, Adrienne M. Flanagan, Udo Oppermann, Adam P. Cribbs   +11 more
wiley   +1 more source

The inclusion of students with visual impairments in the school context

Estação Científica, 2017
This work addresses the inclusion of students with visual impairments in the process of teaching and learning. The objective is to analyze the existing literature and public policies directed to this issue, as well as promoting the importance of ...
Ana Cleia da Luz Lacerda Sousa, Ivaldo Silva Sousa   +1 more
doaj   +1 more source

Current situations in organic cereal seed offer in the Czech Republic [PDF]

, 2011
Organic farmers are obliged, in compliance with the valid legislation, to use seed originating from the organic production when establishing the crop stands.
Capouchova, Ivana, Huda, Petr, Konvalina, Petr, Moudry, Jan, Moudry, Jan (Jr.), Stehno, Zdenek   +5 more
core  

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

Molecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken, Andrea Abel Gutierrez, Imke van Rossum, Cornelia G. Spruijt, Michiel Vermeulen, Guido van Mierlo, Blanca Scheijen, Annemiek B. van Spriel   +7 more
wiley   +1 more source