Results 101 to 110 of about 2,802,986 (296)

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

Molecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff, Manuela Moritz, Dennis Eggert, Anna Worthmann, Joerg Heeren, Henrike Zech, Till S. Clauditz, Waldemar Wilczak, Hartmut Schlüter, Christian S. Betz, Arne Böttcher, Jan Hahn   +11 more
wiley   +1 more source

Classification of faults in friction stir processed composites using a machine learning and ensemble learning approach

Materials Research Express
Aluminium alloy-based surface composites with hard reinforcement particles have a wide scope in the aerospace and automobile manufacturing industries. In this paper, the aluminium composites, manufactured by friction stir processing (FSP) with varying ...
Pragya Saxena, Arunkumar Bongale
doaj   +1 more source

Selection method for HgS crystallization-inducing carriers based on Zeta potential

Gongye shui chuli
The selection and optimization of crystallization-inducing carriers are generally conducted by comparing the removal efficiency of target substances, which features a narrow selection range, time-consuming process, and high consumption of manpower and ...
ZHANG Hang, MA Lirong, YU Lei
doaj   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Selection of the optimal technology for surface mining by multi-criteria analysis

Kuwait Journal of Science, 2015
The selection of optimal technology for surface mining of mineral deposits is a standarddecision-making problem. The aim of this paper is to demonstrate the potential of thecombined AHP and ELECTRE methods in selecting the optimal technology usingthe ...
CVJETKO STOJANOVIC, DEJAN BOGDANOVIC, SNEZANA UROSEVIC   +2 more
doaj  

Equilibrium configurations of nematic liquid crystals on a torus

, 2014
The topology and the geometry of a surface play a fundamental role in determining the equilibrium configurations of thin films of liquid crystals. We propose here a theoretical analysis of a recently introduced surface Frank energy, in the case of two ...
Segatti, Antonio, Snarski, Michael, Veneroni, Marco   +2 more
core   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Velocity selection (without surface tension) in multi-connected Laplacian growth

, 2018
We predict a novel selection phenomenon in nonlinear interface dynamics out of equilibrium. Using a recently developed formalism based on the Schottky-Klein prime functions, we extended the existing integrable theory from a single interface to multiple ...
Mineev-Weinstein, Mark, Vasconcelos, Giovani L.   +1 more
core  

Selective functionalization of patterned glass surfaces

J. Mater. Chem. B, 2014
Tailored writing and specific positioning of molecules on nanostructures is a key step for creating functional materials and nano-optical devices, or interfaces for synthetic machines in various applications. We present a novel approach for the selective functionalization of patterned glass surfaces with functional probes of any nature.
Ploetz, E., Visser, B., Slingenbergh, W., Evers, K., Martinez-Martinez, D., Pei, Y. T., Feringa, B. L., De Hosson, J. Th. M., Cordes, T., van Dorp, W. F.   +9 more
openaire   +4 more sources

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

Molecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli, Alessio Bevilacqua, Mathias Wenes, Denis Migliorini, Lars van der Veen, Sigrid S Skånland, Giusy Di Conza, Kjetil Taskén   +7 more
wiley   +1 more source