Results 81 to 90 of about 9,161 (293)

Problems of technological processes selection in logging

open access: yesIOP Conference Series: Materials Science and Engineering, 2020
Abstract The article deals with current issues of the logging enterprises effective functioning with assortment technology for wood harvesting in the Leningrad region of the North-West Federal District of Russia. A survey of the production activity of a number of enterprises that use logging technology based on harvesters and forwarders ...
V Kalyashov   +4 more
openaire   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner   +14 more
wiley   +1 more source

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata   +10 more
wiley   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

Simulation modeling of logging harvester movements during selective logging

open access: yesJournal of Applied Engineering Science
The purpose of this research is to substantiate the mathematical regularities of the harvester operation, allowing for rapid technical calculations of labor costs with a sufficient level of reliability when performing various logging operations. The article describes the simulation model of harvester movement in the cutting area, created by the authors
Konstantin Rukomojnikov   +1 more
openaire   +1 more source

Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

open access: yesMolecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens   +6 more
wiley   +1 more source

A methodological framework to assess the carbon balance of tropical managed forests

open access: yesCarbon Balance and Management, 2016
Background Managed forests are a major component of tropical landscapes. Production forests as designated by national forest services cover up to 400 million ha, i.e. half of the forested area in the humid tropics.
Camille Piponiot   +8 more
doaj   +1 more source

Distributed Selection in $O ( \log n )$ Time with $O ( n \log \log n )$ Messages

open access: yes, 2015
We consider the selection problem on a completely connected network of $n$ processors with no shared memory. Each processor initially holds a given numeric item of $b$ bits allowed to send a message of $\max ( b, \lg n )$ bits to another processor at a time.
Berman, Piotr, Fukuyama, Junichiro
openaire   +2 more sources

Longitudinal genome‐wide aneuploidy measurements in circulating cell‐free DNA to predict lack of benefit from pembrolizumab in patients with metastatic urothelial cancer

open access: yesMolecular Oncology, EarlyView.
Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi   +14 more
wiley   +1 more source

Tree height reduction after selective logging in a tropical forest

open access: yes, 2016
By harvesting scattered large trees, selective logging increases light availability and thereby stimulates growth and crown expansion at early-life stage among remnant trees. We assessed the effects of logging on total and merchantable bole (i.e., lowest
Hérault, Bruno   +3 more
core   +1 more source

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