Results 81 to 90 of about 70,117 (304)

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra   +6 more
wiley   +1 more source

MAPPING DISTURBANCE FROM SELECTIVE LOGGING IN TROPICAL FORESTS OF THE YUCATAN PENINSULA, MEXICO

open access: yesTropical and Subtropical Agroecosystems, 2020
Background. Mapping selective logging impacts on the Yucatan Peninsula is important to pursuing carbon emissions reduction and biodiversity conservation goals. Objective. To evaluate the effectiveness of applying remote sensing techniques using LANDSAT 8
I.U. Hernandez-Gomez   +4 more
doaj  

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Long-Term Impacts of Selective Logging on Amazon Forest Dynamics from Multi-Temporal Airborne LiDAR

open access: yesRemote Sensing, 2019
Forest degradation is common in tropical landscapes, but estimates of the extent and duration of degradation impacts are highly uncertain. In particular, selective logging is a form of forest degradation that alters canopy structure and function, with ...
Ekena Rangel Pinagé   +5 more
doaj   +1 more source

Understanding changes in the landscape based on a Landsat remote sensing analysis in the Karbi Anglong hills, Assam, India [PDF]

open access: yes, 2016
The landscape of the Karbi Anlong hills (State of Assam, India), south of the Kaziranga National Park, is shaped by small-scale farmers of the Karbi tribe.
Bos, Swen   +4 more
core  

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

Applications of Distributed Optimal Control in Economics-The Case of Forest Management [PDF]

open access: yes
This paper presents a theoretical model to find the optimal selective-logging regime of a size-distributed forest. The law of motion of the economic model is governed by a partial differential equation that describes the evolution of the forest stock ...
Angels Xabadia, Renan Goetz
core  

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

NECROMASS PRODUCTION: STUDIES IN UNDISTURBED AND LOGGED AMAZON FORESTS [PDF]

open access: yes, 2008
Necromass stocks account for up to 20% of carbon stored in tropical forests and have been estimated to be 14–19% of the annual aboveground carbon flux. Both stocks and fluxes of necromass are infrequently measured. In this study, we directly measured the
Keller, Michael M.   +2 more
core   +2 more sources

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

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