Developmental Dynamics, EarlyView.Abstract Background Integrin is an αβ heterodimeric receptor to the extracellular matrix; its binding to the matrix recruits focal adhesions to two NPxY motifs, the tyrosine phosphorylation sites in the cytoplasmic domain. Studies found that replacing tyrosines (Y) with phenylalanines (F) in the motif of β1 integrin displayed little developmental or ...
Josh Haram Bumm +7 more
wiley +1 more source
Pharmacogenetics of Selective Serotonin Reuptake Inhibitors and Associated Adverse Drug Reactions [PDF]
, 2009 Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/90075/1/phco.29.7.822 ...
Ellingrod, Vicki L., Thomas, Kelan L. H.
core +1 more source
Inherited metabolic epilepsies–established diseases, new approaches
Epilepsia Open, EarlyView.Abstract Inherited metabolic epilepsies (IMEs) represent the inherited metabolic disorders (IMDs) in which epilepsy is a prevailing component, often determining other neurodevelopmental outcomes associated with the disorder. The different metabolic pathways affected by individual IMEs are the basis of their rarity and heterogeneity.
Itay Tokatly Latzer, Phillip L. Pearl
wiley +1 more source
The reported use and effectiveness of Hypericum (St John’s wort) on affective symptoms in a depression self-help group [PDF]
, 2002 A recent meta-analysis suggested that Hypericum perforatum (St John’s wort) is an effective treatment for mild to moderate depression and may have a superior side-effect profile to some antidepressant drugs.
Baldwin, D.S. +4 more
core +1 more source
Dose-response effects of selective serotonin reuptake inhibitor monotherapy for the treatment of depression: systematic review of reviews and meta-narrative synthesis [PDF]
, 2022 Chris Johnson +4 more
openalex +1 more source
Hormone replacement therapy [PDF]
, 2012 Martha Hickey, Jane Elliott, Sonia Louise ...
Davison, S., Elliott, C., Hickey, M.
core +2 more sources
Ibrain, EarlyView.In this review, agents such baicalein, troxerutin, epigallocatechin gallate, quercetin, melatonin, valproic acid, lithium, neurosteroid progesterone, as well as minocycline have been implicated as neuroprotective agents for irradiation‐induced neurological deficits. Also, agents such as glucocorticoids, methylphenidate, vitamin E, bisdemethoxycurcumin,
Seidu A. Richard +2 more
wiley +1 more source
Activation of 5-HT 2A Receptor Disrupts Rat Maternal Behavior [PDF]
, 2019 Serotonin 5-HT2A receptor is widely distributed in the central nervous system and plays an important role in sensorimotor function, emotion regulation, motivation, executive control, learning and memory. We investigated its role in rat maternal behavior,
Davis, Collin +3 more
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Is depression a real risk factor for acute myocardial infarction mortality? A retrospective cohort study [PDF]
, 2019 Background: Depression has been associated with a higher risk of cardiovascular events and a higher mortality in patients with one or more comorbidities.
Baldo, V. +7 more
core +1 more source
Neurobiological correlates of obsessive‐compulsive disorder (OCD): A narrative review
Ibrain, EarlyView.Obsessive‐compulsive disorder (OCD) is a common and disabling, as well as underdiagnosed, neuropsychiatric condition characterized by involuntary and unwanted obsessions and/or compulsions often accompanied by states of severe anxiety, distress and shame, as well as other comorbid disorders. Despite the extensive literature available to date, only some
Giulio Perrotta, Anna Sara Liberati
wiley +1 more source