Results 111 to 120 of about 1,856,845 (304)

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

Molecular basis for selective uptake and elimination of organic anions in the kidney by OAT1. [PDF]

Nat Struct Mol Biol, 2023
Parker JL, Kato T, Kuteyi G, Sitsel O, Newstead S.   +4 more
europepmc   +1 more source

Postcard from P. F. Stockler, Local Board, Louisville, Kentucky, to Andrew Johnson, Jr., Louisville, Kentucky, November 6, 1941

, 1941
A postcard from the local board of the Selective Service to Andrew William Johnson, Jr.
United States. Bureau of Selective Service, Stockler, P. F.   +1 more
core  

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

Molecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu, Puspa Das, Xing Zhang, Xiaodong Cheng   +3 more
wiley   +1 more source

Mechanism for the selective uptake of macular carotenoids mediated by the HDL cholesterol receptor SR-BI. [PDF]

Exp Eye Res, 2023
Li B, George EW, Vachali P, Chang FY, Gorusupudi A, Arunkumar R, Giauque NA, Wan Z, Frederick JM, Bernstein PS.   +9 more
europepmc   +1 more source

Postcard from P. F. Stockler, Local Board, Louisville, Kentucky, to Andrew Johnson, Jr., Louisville, Kentucky, November 5, 1942

, 1942
A postcard from the local board of the Selective Service to Andrew William Johnson, Jr.
United States. Bureau of Selective Service, Stockler, P. F.   +1 more
core  

Probucol increases the selective uptake of HDL cholesterol esters by Hep G2 human hepatoma cells.

, 1992
A previous study in rats showed that even though probucol substantially lowers high density lipoprotein (HDL) levels, near-normal mass transport of HDL cholesterol esters (CE) to the liver is maintained by the induction of "selective" (direct) uptake of ...
R C Pittman, B M Richard, M A Pfeuffer
core   +1 more source

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

Molecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic, Rafael Stroggilos, Mladen Marinkovic, Ana Djuric, Suzana Stojanovic‐Rundic, Radmila Jankovic, Sergi Castellvi‐Bel, Remond J.A. Fijneman, Antonia Vlahou, Jerome Zoidakis, Milena Cavic   +10 more
wiley   +1 more source

A Novel Selective Lipid Uptake Pathway Contributing to LDL-Induced Macrophage Foam Cell Formation [PDF]

, 2013
Atherosclerosis is a disease characterized by cholesterol-rich plaques within the intima of medium and large arteries. Cholesterol deposition is thought to occur by infiltration of low-density lipoprotein (LDL) into lesions followed by uptake into ...
Meyer, Jason M.
core   +1 more source

Good's Buffer Based Highly Biocompatible Ionic Liquid Modified PLGA Nanoparticles for the Selective Uptake in Cancer Cells. [PDF]

Mater Chem Front, 2023
Singh G, Dasanayake GS, Chism CM, Vashisth P, Kaur A, Misra SK, Sharp JS, Tanner EEL.   +7 more
europepmc   +1 more source