Results 251 to 260 of about 622,888 (291)
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Fluoxetine, a selective serotonin uptake inhibitor
Clinical Pharmacology & Therapeutics, 1978Fluoxetine is a selective serotonin uptake inhibitor in man. Platelets harvested from subjects to whom fluoxetine was administered (30 mg daily for 1 wk) had a diminished ability to accumulate 3Hâserotonin. The inhibition of uptake was positively correlated with the plasma concentrations of fluoxetine.
L, Lemberger +6 more
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Low density lipoprotein uptake: holoparticle and cholesteryl ester selective uptake
The International Journal of Biochemistry & Cell Biology, 1999Low density lipoproteins (LDL) contain apolipoprotein B-100 and are cholesteryl ester-rich, triglyceride-poor macromolecules, arising from the lipolysis of very low density lipoproteins. This review will describe the receptors responsible for uptake of whole LDL particles (holoparticle uptake), and the selective uptake of LDL cholesteryl ester. The LDL-
D, Rhainds, L, Brissette
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SELECTIVITY AND UPTAKE OF LITHIUM
Comments on Inorganic Chemistry, 2004Lithium salts are widely utilized as psychopharmacological agents for the therapy of bipolar disorders and related illnesses. Although it is readily bioavailable and has just a single biologically relevant oxidation state, its biological activity remains poorly understood. This comment will examine several key issues in this area: 1) Given the chemical
ANH NGUYEN, D. SCOTT BOHLE
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New tetrazole-based selective anandamide uptake inhibitors
Bioorganic & Medicinal Chemistry Letters, 2008A new series of 1,5- and 2,5-disubstituted tetrazoles have been synthesized and evaluated as inhibitors of anandamide cellular uptake. Some of them inhibit the uptake process with a relatively high potency (IC(50)=2.3-5.1microM) and selectively over other proteins involved in endocannabinoid action and metabolism.
Ortar G +7 more
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