Results 71 to 80 of about 11,591 (176)

On-Resin Selenopeptide Catalysts: Synthesis and Applications of Enzyme-Mimetic Reactions and Cyclization of Unsaturated Carboxylic Acids

Molecules
Selenium reagents are useful for selenoenzyme-mimicking reactions, as well as for organic synthesis. However, the reaction waste containing selenium frequently smells unpleasant and exhibits serious toxicity.
Michio Iwaoka, Yua Maese, Kasumi Abe
doaj   +1 more source

Selenium-Containing Amino Acids Protect Dextran Sulfate Sodium-Induced Colitis via Ameliorating Oxidative Stress and Intestinal Inflammation

Journal of Inflammation Research, 2021
Chengxin Shi,1,* Fengli Yue,2,* Feiyu Shi,1 Qian Qin,1 Lizhao Wang,1 Guanghui Wang,1 Lijun Mu,1 Dan Liu,1 Yaguang Li,1 Tianyu Yu,1 Junjun She1 1Department of General Surgery, The First Affiliated Hospital of Xi’an Jiaotong University, Xi’an ...
Shi C, Yue F, Shi F, Qin Q, Wang L, Wang G, Mu L, Liu D, Li Y, Yu T, She J   +10 more
doaj  

Folding of peptides and proteins: role of disulfide bonds, recent developments

Biomolecular Concepts, 2013
Disulfide-containing proteins are ideal models for studies of protein folding as the folding intermediates can be observed, trapped, and separated by HPLC during the folding reaction.
Hidaka Yuji, Shimamoto Shigeru
doaj   +1 more source

DeepSecMS Advances DIA‐Based Selenoproteome Profiling Through Cys‐to‐Sec Proxy Training

Advanced Science
Selenoproteins, defined as proteins containing the 21st amino acid, selenocysteine (Sec, U), are functionally important but rare, with only 25 selenoproteins characterized in the entire human proteome to date.
Chenfang Si, Yamei Yuan, Yu Zong, Liang Qiao, Wen‐Feng Zeng, Yaoyang Zhang   +5 more
doaj   +1 more source

The C-terminal selenenylsulfide of extracellular/non-reduced thioredoxin reductase endows this protein with selectivity to small-molecule electrophilic reagents under oxidative conditions

Frontiers in Molecular Biosciences
Mammalian cytosolic thioredoxin reductase (TrxR1) serves as an antioxidant protein by transferring electrons from NADPH to various substrates. The action of TrxR1 is achieved via reversible changes between NADPH-reduced and non-reduced forms, which ...
Huijun Qin, Chenchen Guo, Bozhen Chen, Hui Huang, Yaping Tian, Liangwei Zhong   +5 more
doaj   +1 more source

Foliar selenium biofortification of soybean: the potential for transformation of mineral selenium into organic forms

Frontiers in Plant Science
IntroductionSelenium (Se) deficiency, stemming from malnutrition in humans and animals, has the potential to disrupt many vital physiological processes, particularly those reliant on specific selenoproteins.
Tomáš Mrština, Lukáš Praus, Jiřina Száková, Lukáš Kaplan, Pavel Tlustoš   +4 more
doaj   +1 more source

Novel selenoprotein neighborhoods suggest specialized biochemical processes

mSystems
Prokaryotic genomes encode selenoproteins sparsely, roughly one protein per 5,000. Finding novel selenoprotein families can expose unknown biological processes that are enabled, or at least enhanced, by having a selenium atom replace a sulfur atom in ...
Daniel H. Haft, Igor Tolstoy
doaj   +1 more source

Defining the methanogenic SECIS element in vivo by targeted mutagenesis

RNA Biology
In all domains of life, Archaea, Eukarya and Bacteria, the unusual amino acid selenocysteine (Sec) is co-translationally incorporated into proteins by recoding a UGA stop codon to a sense codon.
Nils Peiter, Anna Einert, Pauline Just, Frida Jannasch, Marija Najdovska, Michael Rother   +5 more
doaj   +1 more source

Selenocysteine [PDF]

, 2020
openaire   +1 more source

Synergistic Effects of Selenium, Selenoproteins, Selenocysteine and Procyanidin A2 Based on Immune Response and Oxidative Stress. [PDF]

Molecules
Yang L, Ma Y, Wu X, Sun J, Qian R, Liang Y, Zheng B, Zhu J.   +7 more
europepmc   +1 more source