Results 61 to 70 of about 11,591 (176)
Glutathione peroxidase 1 (cellular glutathione peroxidase, EC 1.11.1.9 (GPX1)) is an antioxidant enzyme that plays an important role in scavenging reactive oxygen species to protect cells from oxidative damage.
Sopon Wilaison, Makoto Mori
doaj +1 more source
The relationship between cellular protein content and selenium accumulation in freshwater microalgae
Abstract Variability in the bioconcentration of selenium (Se) by primary producers at the base of the food web results in uncertainty in predictions of bioaccumulation and ecological risk to higher trophic level organisms. Water chemistry, speciation of Se, and periphyton community composition have all been suggested as factors that contribute to ...
Courtney Bogstie +3 more
wiley +1 more source
Efficiency of Mammalian Selenocysteine Incorporation [PDF]
Five components have thus far been identified that are necessary for the incorporation of selenocysteine (Sec) into approximately 25 mammalian proteins. Two of these are cis sequences, a SECIS element in the 3'-untranslated region and a Sec codon (UGA) in the coding region.
Anupama, Mehta +4 more
openaire +2 more sources
ABSTRACT Selenium (Se) is an essential micronutrient that participates in redox regulation and cellular homeostasis. Selenium‐containing ionic liquids (ILsSe) have emerged as hybrid compounds combining the properties of organoselenium molecules with the tunable features of ionic liquids.
Guilherme Schmitt Rieder +17 more
wiley +1 more source
Ion Activation Methods for Top‐Down Proteomics
ABSTRACT Mass spectrometry (MS) has emerged as a premier method used to characterize the sequences of proteins. Top‐down proteomics aims to capture the multiple sources of structural diversity reflected in proteins, such as those that arise from alternative RNA splicing events or the addition of post‐translational modifications. Tandem MS (i.e., MS/MS)
Jada N. Walker, Jennifer S. Brodbelt
wiley +1 more source
Dietary interventions in acute kidney injury: From molecular mechanism to clinical trials
Abstract Ageing impairs renal resilience with an elevated risk of frequent and harmful acute kidney injury (AKI) that causes substantial morbidity and mortality among hospitalized patients. Since different damaging stimuli at the molecular, cellular and functional level contribute to this loss in kidney function, AKI's pathophysiology is heterogeneous ...
Felix C. Koehler +2 more
wiley +1 more source
Synthesis of Oligonucleotide Conjugates Employing a Diselenide Linker
ABSTRACT In this study, we report the synthesis of an alkylene linker containing a terminal 2‐cyanoethyl protected selenium functionality for coupling at the 5'‐end of an oligonucleotide by solid phase synthesis for the preparation of oligonucleotide conjugates.
Shivam Tikoo +2 more
wiley +1 more source
The appearance of selenium in organic synthesis is relatively rare, and thus examples in the literature pertaining to the masking of its considerable reactivity are similarly uncommon.
Stevenson Flemer Jr.
doaj +1 more source
The findings highlight tissue‐specific responses to dietary selenium supplementation, with hepatic antioxidant modulation occurring without changes in plasma parameters, while selenium deposition patterns differed among tissues, emphasizing the complex relationship between selenium sources, metabolism, and antioxidant defense.
Diene France de de Souza +8 more
wiley +1 more source
Selenium hyperaccumulation has little impact on the overall microbiome diversity but rather affects interactions with key plant microbial mutualists, including rhizobia. Abstract Metal hyperaccumulation is prevalent throughout plant evolution, particularly in the legume family (Fabaceae), and acts as a presumed chemical defence against herbivory ...
C. Dotson, C. Kurowski, M. Grillo
wiley +1 more source

